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Protein

Putative DNA (cytosine-5)-methyltransferase

Gene

FV3-083R

Organism
Frog virus 3 (isolate Goorha) (FV-3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Methylates CpG residues.By similarity

Catalytic activityi

S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei62PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChromatin regulator, Methyltransferase, Transferase
LigandS-adenosyl-L-methionine

Protein family/group databases

REBASEi2843. M.Fvi3IP.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative DNA (cytosine-5)-methyltransferase (EC:2.1.1.37)
Gene namesi
ORF Names:FV3-083R
OrganismiFrog virus 3 (isolate Goorha) (FV-3)
Taxonomic identifieri654924 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeAlphairidovirinaeRanavirus
Virus hostiAmbystoma (mole salamanders) [TaxID: 8295]
Dryophytes versicolor (chameleon treefrog) [TaxID: 30343]
Lithobates pipiens (Northern leopard frog) (Rana pipiens) [TaxID: 8404]
Notophthalmus viridescens (Eastern newt) (Triturus viridescens) [TaxID: 8316]
Rana sylvatica (Wood frog) [TaxID: 45438]
Proteomesi
  • UP000008770 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004105861 – 214Putative DNA (cytosine-5)-methyltransferaseAdd BLAST214

Structurei

3D structure databases

ProteinModelPortaliQ67472.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.PROSITE-ProRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR018117. C5_DNA_meth_AS.
IPR029063. SAM-dependent_MTases.
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiView protein in PROSITE
PS00094. C5_MTASE_1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q67472-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRILDLFSGT HSVPKACAQR EGWSCVTVDL ADSDYNVDVL EWDYTKDLKP
60 70 80 90 100
REFDVVWASP PCRYFSKLRE SNIGRGGMTK KSVKEDLETK GLPLLRRAME
110 120 130 140 150
IIAYLQPKKF IVENPDTGRM KEYITEWPHY VVDYCAYSDW GYRKRTRLWT
160 170 180 190 200
DIEGFVPKTC AGKESCPNME RNPSSGRWRH VLATDAGGRG RKGTTRRLRY
210
RVPPAIIVEL LDLC
Length:214
Mass (Da):24,730
Last modified:November 1, 1996 - v1
Checksum:iC0CB3D616F36A222
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U15575 Genomic DNA. Translation: AAA86959.1.
AY548484 Genomic DNA. Translation: AAT09743.1.
RefSeqiYP_031662.1. NC_005946.1.

Genome annotation databases

GeneIDi2947802.
KEGGivg:2947802.

Similar proteinsi

Entry informationi

Entry nameiDNMT_FRG3G
AccessioniPrimary (citable) accession number: Q67472
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 28, 2011
Last sequence update: November 1, 1996
Last modified: September 27, 2017
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families