Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q67472

- DNMT_FRG3G

UniProt

Q67472 - DNMT_FRG3G

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Putative DNA (cytosine-5)-methyltransferase

Gene

FV3-083R

Organism
Frog virus 3 (isolate Goorha) (FV-3)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Methylates CpG residues.By similarity

Catalytic activityi

S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei62 – 621PROSITE-ProRule annotation

GO - Molecular functioni

  1. DNA (cytosine-5-)-methyltransferase activity Source: UniProtKB-EC
  2. DNA binding Source: InterPro

GO - Biological processi

  1. chromatin modification Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulator, Methyltransferase, Transferase

Keywords - Ligandi

S-adenosyl-L-methionine

Protein family/group databases

REBASEi2843. M.Fvi3IP.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative DNA (cytosine-5)-methyltransferase (EC:2.1.1.37)
Gene namesi
ORF Names:FV3-083R
OrganismiFrog virus 3 (isolate Goorha) (FV-3)
Taxonomic identifieri654924 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeRanavirus
Virus hostiAmbystoma (mole salamanders) [TaxID: 8295]
Hyla versicolor (chameleon treefrog) [TaxID: 30343]
Lithobates pipiens (Northern leopard frog) (Rana pipiens) [TaxID: 8404]
Notophthalmus viridescens (Eastern newt) (Triturus viridescens) [TaxID: 8316]
Rana sylvatica (Wood frog) [TaxID: 45438]
ProteomesiUP000008770: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 214214Putative DNA (cytosine-5)-methyltransferasePRO_0000410586Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ67472.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.PROSITE-ProRule annotation

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
InterProiIPR018117. C5_DNA_meth_AS.
IPR029063. SAM-dependent_MTases-like.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiPS00094. C5_MTASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q67472-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRILDLFSGT HSVPKACAQR EGWSCVTVDL ADSDYNVDVL EWDYTKDLKP
60 70 80 90 100
REFDVVWASP PCRYFSKLRE SNIGRGGMTK KSVKEDLETK GLPLLRRAME
110 120 130 140 150
IIAYLQPKKF IVENPDTGRM KEYITEWPHY VVDYCAYSDW GYRKRTRLWT
160 170 180 190 200
DIEGFVPKTC AGKESCPNME RNPSSGRWRH VLATDAGGRG RKGTTRRLRY
210
RVPPAIIVEL LDLC
Length:214
Mass (Da):24,730
Last modified:November 1, 1996 - v1
Checksum:iC0CB3D616F36A222
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U15575 Genomic DNA. Translation: AAA86959.1.
AY548484 Genomic DNA. Translation: AAT09743.1.
RefSeqiYP_031662.1. NC_005946.1.

Genome annotation databases

GeneIDi2947802.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U15575 Genomic DNA. Translation: AAA86959.1 .
AY548484 Genomic DNA. Translation: AAT09743.1 .
RefSeqi YP_031662.1. NC_005946.1.

3D structure databases

ProteinModelPortali Q67472.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

REBASEi 2843. M.Fvi3IP.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2947802.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
InterProi IPR018117. C5_DNA_meth_AS.
IPR029063. SAM-dependent_MTases-like.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
PROSITEi PS00094. C5_MTASE_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Identification and characterization of the frog virus 3 DNA methyltransferase gene."
    Kaur K., Rohozinski J., Goorha R.
    J. Gen. Virol. 76:1937-1943(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Comparative genomic analyses of frog virus 3, type species of the genus Ranavirus (family Iridoviridae)."
    Tan W.G., Barkman T.J., Gregory Chinchar V., Essani K.
    Virology 323:70-84(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiDNMT_FRG3G
AccessioniPrimary (citable) accession number: Q67472
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 28, 2011
Last sequence update: November 1, 1996
Last modified: October 1, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3