Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q67472

- DNMT_FRG3G

UniProt

Q67472 - DNMT_FRG3G

Protein

Putative DNA (cytosine-5)-methyltransferase

Gene

FV3-083R

Organism
Frog virus 3 (isolate Goorha) (FV-3)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Methylates CpG residues.By similarity

    Catalytic activityi

    S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.PROSITE-ProRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei62 – 621PROSITE-ProRule annotation

    GO - Molecular functioni

    1. DNA (cytosine-5-)-methyltransferase activity Source: UniProtKB-EC
    2. DNA binding Source: InterPro

    GO - Biological processi

    1. chromatin modification Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chromatin regulator, Methyltransferase, Transferase

    Keywords - Ligandi

    S-adenosyl-L-methionine

    Protein family/group databases

    REBASEi2843. M.Fvi3IP.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative DNA (cytosine-5)-methyltransferase (EC:2.1.1.37)
    Gene namesi
    ORF Names:FV3-083R
    OrganismiFrog virus 3 (isolate Goorha) (FV-3)
    Taxonomic identifieri654924 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeRanavirus
    Virus hostiAmbystoma (mole salamanders) [TaxID: 8295]
    Hyla versicolor (chameleon treefrog) [TaxID: 30343]
    Lithobates pipiens (Northern leopard frog) (Rana pipiens) [TaxID: 8404]
    Notophthalmus viridescens (Eastern newt) (Triturus viridescens) [TaxID: 8316]
    Rana sylvatica (Wood frog) [TaxID: 45438]
    ProteomesiUP000008770: Genome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 214214Putative DNA (cytosine-5)-methyltransferasePRO_0000410586Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ67472.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.PROSITE-ProRule annotation

    Family and domain databases

    Gene3Di3.40.50.150. 1 hit.
    InterProiIPR018117. C5_DNA_meth_AS.
    IPR029063. SAM-dependent_MTases-like.
    [Graphical view]
    SUPFAMiSSF53335. SSF53335. 1 hit.
    PROSITEiPS00094. C5_MTASE_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q67472-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRILDLFSGT HSVPKACAQR EGWSCVTVDL ADSDYNVDVL EWDYTKDLKP    50
    REFDVVWASP PCRYFSKLRE SNIGRGGMTK KSVKEDLETK GLPLLRRAME 100
    IIAYLQPKKF IVENPDTGRM KEYITEWPHY VVDYCAYSDW GYRKRTRLWT 150
    DIEGFVPKTC AGKESCPNME RNPSSGRWRH VLATDAGGRG RKGTTRRLRY 200
    RVPPAIIVEL LDLC 214
    Length:214
    Mass (Da):24,730
    Last modified:November 1, 1996 - v1
    Checksum:iC0CB3D616F36A222
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U15575 Genomic DNA. Translation: AAA86959.1.
    AY548484 Genomic DNA. Translation: AAT09743.1.
    RefSeqiYP_031662.1. NC_005946.1.

    Genome annotation databases

    GeneIDi2947802.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U15575 Genomic DNA. Translation: AAA86959.1 .
    AY548484 Genomic DNA. Translation: AAT09743.1 .
    RefSeqi YP_031662.1. NC_005946.1.

    3D structure databases

    ProteinModelPortali Q67472.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    REBASEi 2843. M.Fvi3IP.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 2947802.

    Family and domain databases

    Gene3Di 3.40.50.150. 1 hit.
    InterProi IPR018117. C5_DNA_meth_AS.
    IPR029063. SAM-dependent_MTases-like.
    [Graphical view ]
    SUPFAMi SSF53335. SSF53335. 1 hit.
    PROSITEi PS00094. C5_MTASE_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification and characterization of the frog virus 3 DNA methyltransferase gene."
      Kaur K., Rohozinski J., Goorha R.
      J. Gen. Virol. 76:1937-1943(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "Comparative genomic analyses of frog virus 3, type species of the genus Ranavirus (family Iridoviridae)."
      Tan W.G., Barkman T.J., Gregory Chinchar V., Essani K.
      Virology 323:70-84(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiDNMT_FRG3G
    AccessioniPrimary (citable) accession number: Q67472
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 28, 2011
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3