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Protein

Protein VP2

Gene

ORF2

Organism
Sapporo virus (isolate GI/Human/Germany/pJG-Sap01) (Hu/Dresden/pJG-Sap01/DE)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Minor structural protein present in one or two copies per virion. Does not seem to play a role in capsid assembly, but is essential for production of infectious virus (By similarity).By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Protein VP2
Alternative name(s):
Minor capsid protein
Gene namesi
ORF Names:ORF2
OrganismiSapporo virus (isolate GI/Human/Germany/pJG-Sap01) (Hu/Dresden/pJG-Sap01/DE)
Taxonomic identifieri291175 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageCaliciviridaeSapovirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
ProteomesiUP000007049: Genome

Subcellular locationi

Virion. Host cytoplasm By similarity

GO - Cellular componenti

  1. host cell cytoplasm Source: UniProtKB-SubCell
  2. virion Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Host cytoplasm, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 165165Protein VP2PRO_0000342119Add
BLAST

Interactioni

Subunit structurei

May interact with capsid protein.By similarity

Family & Domainsi

Sequence similaritiesi

Belongs to the vesivirus VP2 protein family.Curated

Family and domain databases

InterProiIPR008437. Minor_structural_calicivir.
[Graphical view]
PfamiPF05752. Calici_MSP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q672H9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSWLVGALQT FGSLADVAGT VSNIVYQQRQ AAQLEKQNEL METWMNKQEA
60 70 80 90 100
LQKSQMELTR DLSINGPAAR VQSALDAGFD EVSARRIAGS GERVIWGNLD
110 120 130 140 150
RPIMHAGTMD SIRQTRHLDS LSHSLATFKN GTPFGKPAPP TAKSGRPQAT
160
TAQITIGHNP GSTSV
Length:165
Mass (Da):17,814
Last modified:October 11, 2004 - v1
Checksum:i7D6B7C5D4AB1DBC0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY694184 Genomic RNA. Translation: AAU09267.1.
RefSeqiYP_077280.1. NC_006269.1.

Genome annotation databases

GeneIDi5176813.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY694184 Genomic RNA. Translation: AAU09267.1.
RefSeqiYP_077280.1. NC_006269.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5176813.

Family and domain databases

InterProiIPR008437. Minor_structural_calicivir.
[Graphical view]
PfamiPF05752. Calici_MSP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Structural and functional characterization of sapovirus RNA-dependent RNA polymerase."
    Fullerton S.W., Blaschke M., Coutard B., Gebhardt J., Gorbalenya A., Canard B., Tucker P.A., Rohayem J.
    J. Virol. 81:1858-1871(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiVP2_SVSAP
AccessioniPrimary (citable) accession number: Q672H9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: October 11, 2004
Last modified: January 7, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Miscellaneous

Translated by a ribosomal terminaition-reinitiation process from the bicistronic mRNA coding for VP1 and VP2.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.