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Q66SS1

- Q66SS1_HUMAN

UniProt

Q66SS1 - Q66SS1_HUMAN

Protein
Submitted name:

Paired box gene 6 isoform a

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (05 Feb 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. sequence-specific DNA binding Source: InterPro
    2. sequence-specific DNA binding transcription factor activity Source: InterPro

    GO - Biological processi

    1. multicellular organismal development Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Developmental proteinUniRule annotationSAAS annotation

    Keywords - Biological processi

    Transcription, Transcription regulationUniRule annotationSAAS annotation

    Keywords - Ligandi

    DNA-bindingUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Paired box gene 6 isoform aImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    Nucleus UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    NucleusUniRule annotationSAAS annotation

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA32960.

    PTM / Processingi

    Proteomic databases

    PRIDEiQ66SS1.

    Expressioni

    Gene expression databases

    ArrayExpressiQ66SS1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ66SS1.
    SMRiQ66SS1. Positions 4-136, 211-278.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 paired domain.UniRule annotation
    Contains paired domain.SAAS annotation

    Keywords - Domaini

    HomeoboxUniRule annotation, Paired boxUniRule annotationSAAS annotation

    Phylogenomic databases

    HOVERGENiHBG009115.
    KOiK08031.
    PhylomeDBiQ66SS1.

    Family and domain databases

    Gene3Di1.10.10.10. 2 hits.
    1.10.10.60. 1 hit.
    InterProiIPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR009057. Homeodomain-like.
    IPR001523. Paired_dom.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PfamiPF00046. Homeobox. 1 hit.
    PF00292. PAX. 1 hit.
    [Graphical view]
    PRINTSiPR00027. PAIREDBOX.
    SMARTiSM00389. HOX. 1 hit.
    SM00351. PAX. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 2 hits.
    PROSITEiPS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    PS00034. PAIRED_1. 1 hit.
    PS51057. PAIRED_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q66SS1-1 [UniParc]FASTAAdd to Basket

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    MQNSHSGVNQ LGGVFVNGRP LPDSTRQKIV ELAHSGARPC DISRILQVSN    50
    GCVSKILGRY YETGSIRPRA IGGSKPRVAT PEVVSKIAQY KRECPSIFAW 100
    EIRDRLLSEG VCTNDNIPSV SSINRVLRNL ASEKQQMGAD GMYDKLRMLN 150
    GQTGSWGTRP GWYPGTSVPG QPTQDGCQQQ EGGGENTNSI SSNGEDSDEA 200
    QMRLQLKRKL QRNRTSFTQE QIEALEKEFE RTHYPDVFAR ERLAAKIDLP 250
    EARIQVWFSN RRAKWRREEK LRNQRRQASN TPSHIPISSS FSTSVYQPIP 300
    QPTTPVSSFT SGSMLGRTDT ALTNTYSALP PMPSFTMANN LPMQPPVPSQ 350
    TSSYSCMLPT SPSVNGRSYD TYTPPHMQTH MNSQPMGTSG TTSTGLISPG 400
    VSVPVQVPGS EPDMSQYWPR LQ 422
    Length:422
    Mass (Da):46,683
    Last modified:February 5, 2008 - v1
    Checksum:iC33CDD2C1B13C397
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY707088 mRNA. Translation: AAU12168.1.
    RefSeqiNP_000271.1. NM_000280.4.
    NP_001121084.1. NM_001127612.1.
    NP_001245393.1. NM_001258464.1.
    NP_001245394.1. NM_001258465.1.
    XP_005253012.1. XM_005252955.2.
    XP_005253013.1. XM_005252956.2.
    UniGeneiHs.270303.
    Hs.611376.

    Genome annotation databases

    GeneIDi5080.
    KEGGihsa:5080.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY707088 mRNA. Translation: AAU12168.1 .
    RefSeqi NP_000271.1. NM_000280.4.
    NP_001121084.1. NM_001127612.1.
    NP_001245393.1. NM_001258464.1.
    NP_001245394.1. NM_001258465.1.
    XP_005253012.1. XM_005252955.2.
    XP_005253013.1. XM_005252956.2.
    UniGenei Hs.270303.
    Hs.611376.

    3D structure databases

    ProteinModelPortali Q66SS1.
    SMRi Q66SS1. Positions 4-136, 211-278.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q66SS1.

    Protocols and materials databases

    DNASUi 5080.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 5080.
    KEGGi hsa:5080.

    Organism-specific databases

    CTDi 5080.
    PharmGKBi PA32960.

    Phylogenomic databases

    HOVERGENi HBG009115.
    KOi K08031.
    PhylomeDBi Q66SS1.

    Miscellaneous databases

    GenomeRNAii 5080.
    NextBioi 19596.

    Gene expression databases

    ArrayExpressi Q66SS1.

    Family and domain databases

    Gene3Di 1.10.10.10. 2 hits.
    1.10.10.60. 1 hit.
    InterProi IPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR009057. Homeodomain-like.
    IPR001523. Paired_dom.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    Pfami PF00046. Homeobox. 1 hit.
    PF00292. PAX. 1 hit.
    [Graphical view ]
    PRINTSi PR00027. PAIREDBOX.
    SMARTi SM00389. HOX. 1 hit.
    SM00351. PAX. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 2 hits.
    PROSITEi PS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    PS00034. PAIRED_1. 1 hit.
    PS51057. PAIRED_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Perez-Pinera P., Bray T.L., Vega J.A., Deuel T.F.
      Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ66SS1_HUMAN
    AccessioniPrimary (citable) accession number: Q66SS1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 5, 2008
    Last sequence update: February 5, 2008
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.