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Q66LH7

- Q66LH7_RAT

UniProt

Q66LH7 - Q66LH7_RAT

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Protein
Submitted name:

CENP-C

Gene

Cenpc

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. centromeric DNA binding Source: InterPro

GO - Biological processi

  1. kinetochore assembly Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
CENP-CImported
Gene namesi
Name:CenpcImported
Synonyms:Cenpc1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi1303061. Cenpc.

Subcellular locationi

GO - Cellular componenti

  1. kinetochore Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ66LH7.

Expressioni

Gene expression databases

GenevestigatoriQ66LH7.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4INMX-ray3.50U/V/W/X710-734[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG259274.
HOGENOMiHOG000090256.
HOVERGENiHBG050891.
KOiK11497.

Family and domain databases

Gene3Di2.60.120.10. 1 hit.
InterProiIPR028386. CENP-C/Mif2/cnp3.
IPR028931. CENP-C_mid.
IPR028052. CENP_C_N_dom.
IPR025974. Mif2/CENP-C_cupin.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PANTHERiPTHR16684. PTHR16684. 1 hit.
PfamiPF11699. CENP-C_C. 1 hit.
PF15620. CENP-C_mid. 1 hit.
PF15622. CENP_C_N. 1 hit.
[Graphical view]
SUPFAMiSSF51182. SSF51182. 1 hit.

Sequencei

Sequence statusi: Complete.

Q66LH7-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MASFHLDHLK NYHRRFCRPS RAPNIPTKQG QNMLEILQDC FEEQNSTESL
60 70 80 90 100
SCSTPKEKDI YVQSTGKERQ ASHSESVPIS SRRKEASLQV PAKPSDPADE
110 120 130 140 150
PVQANEVHQK ILSTDVVSKS TPDSTKTSSK GVKGHHGASD ELYLPGGSPV
160 170 180 190 200
VLLGARVSGS QKAISSGGQK RVTSRRSADM QSSNTDISFK TRKRLNFEDK
210 220 230 240 250
VISNTAEIES SASQVEDSIS EEQEGTSSET SQKRDDLSSE IQPQSKKSFS
260 270 280 290 300
ELYLETVNRK SKCSSVVRHT AAVPSPPYPP NDMKLLEDEF IIDGPDRSFS
310 320 330 340 350
SQPWVVIPRK GHHMPFPENI AVPQGKKSRE KPHRLSEKTL VSNTQTDKTG
360 370 380 390 400
PVEEAQLSVE EKLGTTLTNE LENDCRSTEN KTHSENAKKP SARKRTVKQK
410 420 430 440 450
QRRPSKPNIA QELSMGQNET ENRNMSKIGQ DKLQINSKRN MEDHEEVRNE
460 470 480 490 500
PTPKKPVPAL GNKKEKDSTQ ANKEKSRKKC FSRESKRKSV PKEVTLASRR
510 520 530 540 550
GRRTSQHPSE WWLVKPSEGS VDGNSSKENE SSILYPNRKK QTKRNHVSEN
560 570 580 590 600
TEKKPVPSKR KKKEISSREL KSLNVKGSGG NDDISTSQRK PLQNIDADPT
610 620 630 640 650
QKSLHCSGPT RGSEDQNSDM ISQNVHLKTR SEQHRSKTQM ESTSNSEVCK
660 670 680 690 700
HSVWEESGPS RFKNLEMPGR SNSEVGDEKD QKSLDLKTRS SNMVPNRNLH
710 720 730 740 750
HKLVLPSNSP NVRRSNRIRL KPLEYWRGER IDYQESSSGR LVLEIVSPAS
760 770 780 790 800
ESVKRKAKRN LDKVNKETNK KRIHLDNPTK TKIKVSLDIP LGDPFQATLA
810 820 830 840 850
KDPETREIVP MDLIRPRDTY HFFVEQHGLK VYKTLNTTFF STGKLVLGPH
860 870 880 890 900
EEKGKQHVGQ DILVFYVNFG DLLCTLHETP YMLTTGDSFY VPSGNHYNIK
910
NLLNVESCLL FTQIKR
Length:916
Mass (Da):103,334
Last modified:October 11, 2004 - v1
Checksum:i015E3614EC926C74
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY693788 mRNA. Translation: AAU04621.1.
RefSeqiNP_001004098.1. NM_001004098.1.
UniGeneiRn.85211.

Genome annotation databases

GeneIDi305270.
KEGGirno:305270.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY693788 mRNA. Translation: AAU04621.1 .
RefSeqi NP_001004098.1. NM_001004098.1.
UniGenei Rn.85211.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4INM X-ray 3.50 U/V/W/X 710-734 [» ]
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi Q66LH7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 305270.
KEGGi rno:305270.

Organism-specific databases

CTDi 1060.
RGDi 1303061. Cenpc.

Phylogenomic databases

eggNOGi NOG259274.
HOGENOMi HOG000090256.
HOVERGENi HBG050891.
KOi K11497.

Miscellaneous databases

NextBioi 654308.

Gene expression databases

Genevestigatori Q66LH7.

Family and domain databases

Gene3Di 2.60.120.10. 1 hit.
InterProi IPR028386. CENP-C/Mif2/cnp3.
IPR028931. CENP-C_mid.
IPR028052. CENP_C_N_dom.
IPR025974. Mif2/CENP-C_cupin.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view ]
PANTHERi PTHR16684. PTHR16684. 1 hit.
Pfami PF11699. CENP-C_C. 1 hit.
PF15620. CENP-C_mid. 1 hit.
PF15622. CENP_C_N. 1 hit.
[Graphical view ]
SUPFAMi SSF51182. SSF51182. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Adaptive evolution of centromere proteins in plants and animals."
    Talbert P.B., Bryson T.D., Henikoff S.
    J. Biol. 3:18-18(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Sprague-DawleyImported.
  2. "A conserved mechanism for centromeric nucleosome recognition by centromere protein CENP-C."
    Kato H., Jiang J., Zhou B.R., Rozendaal M., Feng H., Ghirlando R., Xiao T.S., Straight A.F., Bai Y.
    Science 340:1110-1113(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.50 ANGSTROMS) OF 710-734.

Entry informationi

Entry nameiQ66LH7_RAT
AccessioniPrimary (citable) accession number: Q66LH7
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2004
Last sequence update: October 11, 2004
Last modified: October 29, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3