Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q66LH7

- Q66LH7_RAT

UniProt

Q66LH7 - Q66LH7_RAT

Protein
Submitted name:

CENP-C

Gene

Cenpc

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (11 Oct 2004)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. centromeric DNA binding Source: InterPro

    GO - Biological processi

    1. kinetochore assembly Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    CENP-CImported
    Gene namesi
    Name:CenpcImported
    Synonyms:Cenpc1Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi1303061. Cenpc.

    Subcellular locationi

    GO - Cellular componenti

    1. kinetochore Source: InterPro

    PTM / Processingi

    Proteomic databases

    PaxDbiQ66LH7.

    Expressioni

    Gene expression databases

    GenevestigatoriQ66LH7.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4INMX-ray3.50U/V/W/X710-734[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG259274.
    HOGENOMiHOG000090256.
    HOVERGENiHBG050891.
    InParanoidiQ66LH7.
    KOiK11497.

    Family and domain databases

    Gene3Di2.60.120.10. 1 hit.
    InterProiIPR028386. CENP-C/Mif2/cnp3.
    IPR028931. CENP-C_mid.
    IPR028052. CENP_C_N_dom.
    IPR025974. Mif2/CENP-C_cupin.
    IPR014710. RmlC-like_jellyroll.
    IPR011051. RmlC_Cupin.
    [Graphical view]
    PANTHERiPTHR16684. PTHR16684. 1 hit.
    PfamiPF11699. CENP-C_C. 1 hit.
    PF15620. CENP-C_mid. 1 hit.
    PF15622. CENP_C_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF51182. SSF51182. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q66LH7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASFHLDHLK NYHRRFCRPS RAPNIPTKQG QNMLEILQDC FEEQNSTESL    50
    SCSTPKEKDI YVQSTGKERQ ASHSESVPIS SRRKEASLQV PAKPSDPADE 100
    PVQANEVHQK ILSTDVVSKS TPDSTKTSSK GVKGHHGASD ELYLPGGSPV 150
    VLLGARVSGS QKAISSGGQK RVTSRRSADM QSSNTDISFK TRKRLNFEDK 200
    VISNTAEIES SASQVEDSIS EEQEGTSSET SQKRDDLSSE IQPQSKKSFS 250
    ELYLETVNRK SKCSSVVRHT AAVPSPPYPP NDMKLLEDEF IIDGPDRSFS 300
    SQPWVVIPRK GHHMPFPENI AVPQGKKSRE KPHRLSEKTL VSNTQTDKTG 350
    PVEEAQLSVE EKLGTTLTNE LENDCRSTEN KTHSENAKKP SARKRTVKQK 400
    QRRPSKPNIA QELSMGQNET ENRNMSKIGQ DKLQINSKRN MEDHEEVRNE 450
    PTPKKPVPAL GNKKEKDSTQ ANKEKSRKKC FSRESKRKSV PKEVTLASRR 500
    GRRTSQHPSE WWLVKPSEGS VDGNSSKENE SSILYPNRKK QTKRNHVSEN 550
    TEKKPVPSKR KKKEISSREL KSLNVKGSGG NDDISTSQRK PLQNIDADPT 600
    QKSLHCSGPT RGSEDQNSDM ISQNVHLKTR SEQHRSKTQM ESTSNSEVCK 650
    HSVWEESGPS RFKNLEMPGR SNSEVGDEKD QKSLDLKTRS SNMVPNRNLH 700
    HKLVLPSNSP NVRRSNRIRL KPLEYWRGER IDYQESSSGR LVLEIVSPAS 750
    ESVKRKAKRN LDKVNKETNK KRIHLDNPTK TKIKVSLDIP LGDPFQATLA 800
    KDPETREIVP MDLIRPRDTY HFFVEQHGLK VYKTLNTTFF STGKLVLGPH 850
    EEKGKQHVGQ DILVFYVNFG DLLCTLHETP YMLTTGDSFY VPSGNHYNIK 900
    NLLNVESCLL FTQIKR 916
    Length:916
    Mass (Da):103,334
    Last modified:October 11, 2004 - v1
    Checksum:i015E3614EC926C74
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY693788 mRNA. Translation: AAU04621.1.
    RefSeqiNP_001004098.1. NM_001004098.1.
    UniGeneiRn.85211.

    Genome annotation databases

    GeneIDi305270.
    KEGGirno:305270.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY693788 mRNA. Translation: AAU04621.1 .
    RefSeqi NP_001004098.1. NM_001004098.1.
    UniGenei Rn.85211.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4INM X-ray 3.50 U/V/W/X 710-734 [» ]
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi Q66LH7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 305270.
    KEGGi rno:305270.

    Organism-specific databases

    CTDi 1060.
    RGDi 1303061. Cenpc.

    Phylogenomic databases

    eggNOGi NOG259274.
    HOGENOMi HOG000090256.
    HOVERGENi HBG050891.
    InParanoidi Q66LH7.
    KOi K11497.

    Miscellaneous databases

    NextBioi 654308.

    Gene expression databases

    Genevestigatori Q66LH7.

    Family and domain databases

    Gene3Di 2.60.120.10. 1 hit.
    InterProi IPR028386. CENP-C/Mif2/cnp3.
    IPR028931. CENP-C_mid.
    IPR028052. CENP_C_N_dom.
    IPR025974. Mif2/CENP-C_cupin.
    IPR014710. RmlC-like_jellyroll.
    IPR011051. RmlC_Cupin.
    [Graphical view ]
    PANTHERi PTHR16684. PTHR16684. 1 hit.
    Pfami PF11699. CENP-C_C. 1 hit.
    PF15620. CENP-C_mid. 1 hit.
    PF15622. CENP_C_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51182. SSF51182. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Adaptive evolution of centromere proteins in plants and animals."
      Talbert P.B., Bryson T.D., Henikoff S.
      J. Biol. 3:18-18(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Sprague-DawleyImported.
    2. "A conserved mechanism for centromeric nucleosome recognition by centromere protein CENP-C."
      Kato H., Jiang J., Zhou B.R., Rozendaal M., Feng H., Ghirlando R., Xiao T.S., Straight A.F., Bai Y.
      Science 340:1110-1113(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (3.50 ANGSTROMS) OF 710-734.

    Entry informationi

    Entry nameiQ66LH7_RAT
    AccessioniPrimary (citable) accession number: Q66LH7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2004
    Last sequence update: October 11, 2004
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3