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Protein
Submitted name:

Igk protein

Gene

Igk

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Igk proteinImported
Gene namesi
Name:IgkImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi43 ↔ 112Combined sources
Disulfide bondi158 ↔ 218Combined sources

Proteomic databases

PRIDEiQ66JS7.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1ACYX-ray3.00L21-235[»]
4BKLX-ray3.25B21-238[»]
ProteinModelPortaliQ66JS7.
SMRiQ66JS7. Positions 21-237.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ66JS7.

Family & Domainsi

Keywords - Domaini

Immunoglobulin domainSAAS annotation

Phylogenomic databases

HOGENOMiHOG000059537.
HOVERGENiHBG018013.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 2 hits.
PS00290. IG_MHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q66JS7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METDTLLLWV LLLWVPGSTG DIVLTQSPAS LAVSLGQRAT ISCRASQSVS
60 70 80 90 100
TSTYSYMHWY QQKPGQPPKL LIKYASNLES GVPARFSGSG SGTDFTLNIH
110 120 130 140 150
PVEEEDTATY YCQHSWEIPW TFGGGTNLEI KRADAAPTVS IFPPSSEQLT
160 170 180 190 200
SGGASVVCFL NNFYPKDINV KWKIDGSERQ NGVLNSWTDQ DSKDSTYSMS
210 220 230
STLTLTKDEY ERHNSYTCEA THKTSTSPIV KSFNRNEC
Length:238
Mass (Da):26,317
Last modified:October 11, 2004 - v1
Checksum:iC1AF406948D76423
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC080787 mRNA. Translation: AAH80787.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC080787 mRNA. Translation: AAH80787.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1ACYX-ray3.00L21-235[»]
4BKLX-ray3.25B21-238[»]
ProteinModelPortaliQ66JS7.
SMRiQ66JS7. Positions 21-237.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ66JS7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOGENOMiHOG000059537.
HOVERGENiHBG018013.

Miscellaneous databases

EvolutionaryTraceiQ66JS7.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 2 hits.
PS00290. IG_MHC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Crystal structure of the principal neutralization site of HIV-1."
    Ghiara J.B., Stura E.A., Stanfield R.L., Profy A.T., Wilson I.A.
    Science 264:82-85(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.00 ANGSTROMS) OF 21-235, DISULFIDE BONDS.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/NImported.
    Tissue: ColonImported.
  3. "Epitope-specific antibody response is controlled by immunoglobulin V(H) polymorphisms."
    Raposo B., Dobritzsch D., Ge C., Ekman D., Xu B., Lindh I., Forster M., Uysal H., Nandakumar K.S., Schneider G., Holmdahl R.
    J. Exp. Med. 211:405-411(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.25 ANGSTROMS) OF 21-238, DISULFIDE BONDS.

Entry informationi

Entry nameiQ66JS7_MOUSE
AccessioniPrimary (citable) accession number: Q66JS7
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2004
Last sequence update: October 11, 2004
Last modified: June 24, 2015
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.