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Q66JJ3 (ADPRM_XENTR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
EC=3.6.1.13
EC=3.6.1.16
EC=3.6.1.53
Alternative name(s):
ADPRibase-Mn
CDP-choline phosphohydrolase
Gene names
Name:adprm
OrganismXenopus tropicalis (Western clawed frog) (Silurana tropicalis) [Reference proteome]
Taxonomic identifier8364 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Silurana

Protein attributes

Sequence length342 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose By similarity.

Catalytic activity

CDP-choline + H2O = CMP + phosphocholine.

ADP-D-ribose + H2O = AMP + D-ribose 5-phosphate.

CDP-glycerol + H2O = CMP + sn-glycerol 3-phosphate.

Cofactor

Magnesium By similarity.

Subunit structure

Monomer By similarity.

Sequence similarities

Belongs to the ADPRibase-Mn family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 342342Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
PRO_0000286572

Sites

Metal binding181Zinc 1 By similarity
Metal binding201Zinc 1 By similarity
Metal binding671Zinc 1 By similarity
Metal binding671Zinc 2 By similarity
Metal binding1031Zinc 2 By similarity
Metal binding2391Zinc 2 By similarity
Metal binding2761Zinc 2 By similarity
Metal binding2781Zinc 1 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q66JJ3 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 36A972E0881FAC82

FASTA34239,398
        10         20         30         40         50         60 
MESKRMEEPY FTFGIIADIQ YADMDNRFNY LKTSMRYYRN SLTQLKAAVE EWAMESIKPA 

        70         80         90        100        110        120 
FILQLGDIID GINTKDKSSK TALERVLVEM DKLPIQFHHV WGNHEFYNFS REYLNGSKLN 

       130        140        150        160        170        180 
SQARGDRIDR GGGTSENGEF NDESFYAYHF SPCPKFRFLL IDGYDLSPIG REKTSPKYDI 

       190        200        210        220        230        240 
ALNLLKEKNP NEDLNSPTGL EEVQFVLFNG GISPSQLDWM ERVLTSSDEK EENVFVVSHL 

       250        260        270        280        290        300 
PVHPDAADPM CLVWNYPEVL SVLQSHPCVV GYLAGHNHEG RYCMDPYGIH HLTFSGVIET 

       310        320        330        340 
PPESRAFGTM YVYEDKMVLK GRGLVEDRTL YYRDPKNKAE RH

« Hide

References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Embryo.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC080891 mRNA. Translation: AAH80891.1.
RefSeqNP_001008013.1. NM_001008012.1.
UniGeneStr.26786.

3D structure databases

ProteinModelPortalQ66JJ3.
SMRQ66JJ3. Positions 8-333.
ModBaseSearch...

Protein-protein interaction databases

STRING8364.ENSXETP00000024142.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID493375.
KEGGxtr:493375.

Organism-specific databases

CTD56985.
XenbaseXB-GENE-5815851. adprm.

Phylogenomic databases

eggNOGCOG1409.
HOGENOMHOG000154875.
HOVERGENHBG100432.
InParanoidQ66JJ3.
KOK01517.
OrthoDBEOG4TXBSP.

Gene expression databases

BgeeQ66JJ3.

Family and domain databases

InterProIPR004843. Metallo_PEstase_dom.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameADPRM_XENTR
AccessionPrimary (citable) accession number: Q66JJ3
Entry history
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: October 11, 2004
Last modified: April 3, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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