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Protein

Translationally-controlled tumor protein homolog

Gene

tpt1

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Involved in calcium binding and microtubule stabilization.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalcium

Names & Taxonomyi

Protein namesi
Recommended name:
Translationally-controlled tumor protein homolog
Short name:
TCTP
Gene namesi
Name:tpt1
ORF Names:TGas127d21.1
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-854747 tpt1

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002112781 – 172Translationally-controlled tumor protein homologAdd BLAST172

Proteomic databases

PaxDbiQ66JC5

Expressioni

Gene expression databases

BgeeiENSXETG00000014661

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000032120

Structurei

3D structure databases

ProteinModelPortaliQ66JC5
SMRiQ66JC5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 172TCTPPROSITE-ProRule annotationAdd BLAST172

Sequence similaritiesi

Belongs to the TCTP family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1727 Eukaryota
ENOG4111FVP LUCA
GeneTreeiENSGT00390000006051
HOGENOMiHOG000203361
HOVERGENiHBG002282
InParanoidiQ66JC5
OMAiFCIGENM
OrthoDBiEOG091G0OTA
TreeFamiTF300238

Family and domain databases

Gene3Di2.170.150.10, 1 hit
InterProiView protein in InterPro
IPR011057 Mss4-like_sf
IPR011323 Mss4/transl-control_tumor
IPR034737 TCTP
IPR018103 Translation_control_tumour_CS
IPR018105 Translational_control_tumour_p
PANTHERiPTHR11991 PTHR11991, 1 hit
PfamiView protein in Pfam
PF00838 TCTP, 1 hit
PRINTSiPR01653 TCTPROTEIN
SUPFAMiSSF51316 SSF51316, 1 hit
PROSITEiView protein in PROSITE
PS01002 TCTP_1, 1 hit
PS01003 TCTP_2, 1 hit
PS51797 TCTP_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q66JC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIIYKDTVTE DEMFSDIYKI AETPDGMCFE VEGKIIQRVE GAIDDALIGG
60 70 80 90 100
NASAECQEED IGGATTVSGV DIVINHKLQE TGFTKDSYKN YIKDYVKLVK
110 120 130 140 150
AKLEETDPDR VKPFMKGIQD RVKLILGNFK NYQFYTGERM NPDGMVALLD
160 170
YREDGVTPFM IFFKDGLISE KC
Length:172
Mass (Da):19,438
Last modified:October 11, 2004 - v1
Checksum:i50237740C5FC8415
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR848168 mRNA Translation: CAJ83419.1
BC080968 mRNA Translation: AAH80968.1
RefSeqiNP_001008074.1, NM_001008073.3
UniGeneiStr.64795

Genome annotation databases

EnsembliENSXETT00000032120; ENSXETP00000032120; ENSXETG00000014661
GeneIDi493436
KEGGixtr:493436

Similar proteinsi

Entry informationi

Entry nameiTCTP_XENTR
AccessioniPrimary (citable) accession number: Q66JC5
Secondary accession number(s): Q28EM6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: October 11, 2004
Last modified: March 28, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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