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Protein

Translationally-controlled tumor protein homolog

Gene

tpt1

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in calcium binding and microtubule stabilization.By similarity

Keywords - Ligandi

Calcium

Names & Taxonomyi

Protein namesi
Recommended name:
Translationally-controlled tumor protein homolog
Short name:
TCTP
Gene namesi
Name:tpt1
ORF Names:TGas127d21.1
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-854747. tpt1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 172172Translationally-controlled tumor protein homologPRO_0000211278Add
BLAST

Proteomic databases

PaxDbiQ66JC5.

Expressioni

Gene expression databases

BgeeiQ66JC5.

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000032120.

Structurei

3D structure databases

ProteinModelPortaliQ66JC5.
SMRiQ66JC5. Positions 1-172.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 172172TCTPPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the TCTP family.PROSITE-ProRule annotation
Contains 1 TCTP domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1727. Eukaryota.
ENOG4111FVP. LUCA.
GeneTreeiENSGT00390000006051.
HOGENOMiHOG000203361.
HOVERGENiHBG002282.
InParanoidiQ66JC5.
OMAiDIMANIK.
OrthoDBiEOG7SJD61.
TreeFamiTF300238.

Family and domain databases

Gene3Di2.170.150.10. 1 hit.
InterProiIPR011057. Mss4-like.
IPR011323. Mss4/transl-control_tumor.
IPR018103. Translation_control_tumour_CS.
IPR018105. Translational_control_tumour_p.
[Graphical view]
PANTHERiPTHR11991. PTHR11991. 1 hit.
PfamiPF00838. TCTP. 1 hit.
[Graphical view]
PRINTSiPR01653. TCTPROTEIN.
SUPFAMiSSF51316. SSF51316. 1 hit.
PROSITEiPS01002. TCTP_1. 1 hit.
PS01003. TCTP_2. 1 hit.
PS51797. TCTP_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q66JC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIIYKDTVTE DEMFSDIYKI AETPDGMCFE VEGKIIQRVE GAIDDALIGG
60 70 80 90 100
NASAECQEED IGGATTVSGV DIVINHKLQE TGFTKDSYKN YIKDYVKLVK
110 120 130 140 150
AKLEETDPDR VKPFMKGIQD RVKLILGNFK NYQFYTGERM NPDGMVALLD
160 170
YREDGVTPFM IFFKDGLISE KC
Length:172
Mass (Da):19,438
Last modified:October 11, 2004 - v1
Checksum:i50237740C5FC8415
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR848168 mRNA. Translation: CAJ83419.1.
BC080968 mRNA. Translation: AAH80968.1.
RefSeqiNP_001008074.1. NM_001008073.3.
UniGeneiStr.64795.

Genome annotation databases

EnsembliENSXETT00000032120; ENSXETP00000032120; ENSXETG00000014661.
GeneIDi493436.
KEGGixtr:493436.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR848168 mRNA. Translation: CAJ83419.1.
BC080968 mRNA. Translation: AAH80968.1.
RefSeqiNP_001008074.1. NM_001008073.3.
UniGeneiStr.64795.

3D structure databases

ProteinModelPortaliQ66JC5.
SMRiQ66JC5. Positions 1-172.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000032120.

Proteomic databases

PaxDbiQ66JC5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSXETT00000032120; ENSXETP00000032120; ENSXETG00000014661.
GeneIDi493436.
KEGGixtr:493436.

Organism-specific databases

CTDi7178.
XenbaseiXB-GENE-854747. tpt1.

Phylogenomic databases

eggNOGiKOG1727. Eukaryota.
ENOG4111FVP. LUCA.
GeneTreeiENSGT00390000006051.
HOGENOMiHOG000203361.
HOVERGENiHBG002282.
InParanoidiQ66JC5.
OMAiDIMANIK.
OrthoDBiEOG7SJD61.
TreeFamiTF300238.

Gene expression databases

BgeeiQ66JC5.

Family and domain databases

Gene3Di2.170.150.10. 1 hit.
InterProiIPR011057. Mss4-like.
IPR011323. Mss4/transl-control_tumor.
IPR018103. Translation_control_tumour_CS.
IPR018105. Translational_control_tumour_p.
[Graphical view]
PANTHERiPTHR11991. PTHR11991. 1 hit.
PfamiPF00838. TCTP. 1 hit.
[Graphical view]
PRINTSiPR01653. TCTPROTEIN.
SUPFAMiSSF51316. SSF51316. 1 hit.
PROSITEiPS01002. TCTP_1. 1 hit.
PS01003. TCTP_2. 1 hit.
PS51797. TCTP_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Sanger Xenopus tropicalis EST/cDNA project
    Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Gastrula.
  2. NIH - Xenopus Gene Collection (XGC) project
    Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Embryo.

Entry informationi

Entry nameiTCTP_XENTR
AccessioniPrimary (citable) accession number: Q66JC5
Secondary accession number(s): Q28EM6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: October 11, 2004
Last modified: July 6, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.