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Protein
Submitted name:

Serine (Or cysteine) peptidase inhibitor, clade A, member 5

Gene

Serpina5

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • serine-type endopeptidase inhibitor activity Source: RGD

GO - Biological processi

  • negative regulation of proteolysis Source: RGD
  • seminal vesicle development Source: RGD

Protein family/group databases

MEROPSiI04.004.

Names & Taxonomyi

Protein namesi
Submitted name:
Serine (Or cysteine) peptidase inhibitor, clade A, member 5Imported
Submitted name:
Serpina5 proteinImported
Gene namesi
Name:Serpina5Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi619817. Serpina5.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_501014128420 – 406Sequence analysisAdd BLAST387

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 406SERPINInterPro annotationAdd BLAST358

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2392. Eukaryota.
COG4826. LUCA.
HOVERGENiHBG005957.
KOiK03913.
TreeFamiTF343201.

Family and domain databases

InterProiView protein in InterPro
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiView protein in Pfam
PF00079. Serpin. 1 hit.
SMARTiView protein in SMART
SM00093. SERPIN. 1 hit.
SUPFAMiSSF56574. SSF56574. 1 hit.

Sequencei

Sequence statusi: Complete.

Q66HL5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRFFPILCLV LFFSHGVASR QRSHSKEKKK SKESSVGAVG TSRSRDFAFR
60 70 80 90 100
LYRALASEAP GQNVFFSPMS VSMSLGMLSL GSGLKTKAQI LEGLGLSLQQ
110 120 130 140 150
GQEDMLHKGF QQLLQQFSQP SDGLQLSLGS ALFTDPAVHI RDHFLSAMKT
160 170 180 190 200
LYMSDMFSTN FGNPESAKKQ INDYVAKKTN GKIVDLIKDL DSTHVMVVVN
210 220 230 240 250
YIFFKAKWQT AFSSTNTHKM DYHVTPKKTI QVPMMNREDI YSYILDQNIS
260 270 280 290 300
CTVVGIPYQG NTFALFILPS EGKMKRVEDG LDERTLRNWL KMFTKRQLDL
310 320 330 340 350
YLPKFSIEGT YKLEKILPKL GIQDIFTTHA DLSGLTDHTN IKLSEMVHKS
360 370 380 390 400
MVEVDESGTT AAASTGILFT LRSARPSSLK VEFTRPFLVV IMDGTNLYFI

GKVIQP
Length:406
Mass (Da):45,608
Last modified:October 11, 2004 - v1
Checksum:i224DC0E29EE5F68D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC081797 mRNA. Translation: AAH81797.1.
BC097315 mRNA. Translation: AAH97315.1.
RefSeqiNP_001231668.1. NM_001244739.1.
NP_075246.3. NM_022957.3.
UniGeneiRn.30006.

Genome annotation databases

GeneIDi65051.
KEGGirno:65051.
UCSCiRGD:619817. rat.

Similar proteinsi

Entry informationi

Entry nameiQ66HL5_RAT
AccessioniPrimary (citable) accession number: Q66HL5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2004
Last sequence update: October 11, 2004
Last modified: August 30, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)