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Protein

Monocarboxylate transporter 13

Gene

Slc16a13

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Symport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Monocarboxylate transporter 13
Short name:
MCT 13
Alternative name(s):
Solute carrier family 16 member 13
Gene namesi
Name:Slc16a13
Synonyms:Mct13
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1359138. Slc16a13.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 10CytoplasmicSequence analysis10
Transmembranei11 – 31HelicalSequence analysisAdd BLAST21
Transmembranei52 – 72HelicalSequence analysisAdd BLAST21
Transmembranei81 – 101HelicalSequence analysisAdd BLAST21
Transmembranei106 – 126HelicalSequence analysisAdd BLAST21
Transmembranei139 – 159HelicalSequence analysisAdd BLAST21
Transmembranei172 – 192HelicalSequence analysisAdd BLAST21
Transmembranei221 – 241HelicalSequence analysisAdd BLAST21
Transmembranei244 – 264HelicalSequence analysisAdd BLAST21
Transmembranei283 – 303HelicalSequence analysisAdd BLAST21
Transmembranei309 – 329HelicalSequence analysisAdd BLAST21
Transmembranei338 – 358HelicalSequence analysisAdd BLAST21
Transmembranei374 – 394HelicalSequence analysisAdd BLAST21
Topological domaini395 – 428CytoplasmicSequence analysisAdd BLAST34

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002871891 – 428Monocarboxylate transporter 13Add BLAST428

Proteomic databases

PaxDbiQ66HE2.

Expressioni

Gene expression databases

BgeeiENSRNOG00000018785.
GenevisibleiQ66HE2. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000025403.

Structurei

3D structure databases

ProteinModelPortaliQ66HE2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2504. Eukaryota.
COG0477. LUCA.
GeneTreeiENSGT00760000118926.
HOGENOMiHOG000280688.
HOVERGENiHBG106552.
InParanoidiQ66HE2.
KOiK08189.
OMAiDWDPLSA.
OrthoDBiEOG091G05SW.
PhylomeDBiQ66HE2.
TreeFamiTF313792.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q66HE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVHRTEPPDG GWGWMVVLSA FFQSALVFGV LRSFGVFFVE FVAAFEEQAA
60 70 80 90 100
RVSWIASIGI AVQQFGSPIG SALSTKLGPR PVVMTGGILA ALGMLLASFA
110 120 130 140 150
TSLTHLYLSI GLLSGSGWAL TFTPTLACLS RYFSQRRSLA MGLALTGVGI
160 170 180 190 200
SSFAFAPLFQ WLLNNYAWRG ALLLVSALSL HLVACGALLR PLSLTEDTAV
210 220 230 240 250
GGPWAQITSL LCHGPFLRYT VALTLINTGY FIPYVHLVAH LQDLGWDPLP
260 270 280 290 300
AAFLLSVAAI SDLVGRVASG WLGDAVPGPV ARLLMLWTTL TGVSLALFPV
310 320 330 340 350
AQASTTLVVL AVAYGFTSGA LTPVAFSVIP ELVGTGRIYC GLGLVQMIES
360 370 380 390 400
VGGLLGAPLS GYLRDVTGNY TASFVVAGAF LLAGSGVLIT LPHFFSCISL
410 420
STSRPQDLVI EAPDTKIPLP KEEGLGEN
Length:428
Mass (Da):44,993
Last modified:October 11, 2004 - v1
Checksum:i7AC65745D23D3A79
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC081902 mRNA. Translation: AAH81902.1.
RefSeqiNP_001005530.1. NM_001005530.1.
UniGeneiRn.23260.

Genome annotation databases

EnsembliENSRNOT00000025403; ENSRNOP00000025403; ENSRNOG00000018785.
GeneIDi287451.
KEGGirno:287451.
UCSCiRGD:1359138. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC081902 mRNA. Translation: AAH81902.1.
RefSeqiNP_001005530.1. NM_001005530.1.
UniGeneiRn.23260.

3D structure databases

ProteinModelPortaliQ66HE2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000025403.

Proteomic databases

PaxDbiQ66HE2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000025403; ENSRNOP00000025403; ENSRNOG00000018785.
GeneIDi287451.
KEGGirno:287451.
UCSCiRGD:1359138. rat.

Organism-specific databases

CTDi201232.
RGDi1359138. Slc16a13.

Phylogenomic databases

eggNOGiKOG2504. Eukaryota.
COG0477. LUCA.
GeneTreeiENSGT00760000118926.
HOGENOMiHOG000280688.
HOVERGENiHBG106552.
InParanoidiQ66HE2.
KOiK08189.
OMAiDWDPLSA.
OrthoDBiEOG091G05SW.
PhylomeDBiQ66HE2.
TreeFamiTF313792.

Miscellaneous databases

PROiQ66HE2.

Gene expression databases

BgeeiENSRNOG00000018785.
GenevisibleiQ66HE2. RN.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMOT13_RAT
AccessioniPrimary (citable) accession number: Q66HE2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: October 11, 2004
Last modified: September 7, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.