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Protein

Gametogenetin

Gene

Ggn

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

May be involved in spermatogenesis.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Developmental protein

Keywords - Biological processi

Differentiation, Spermatogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Gametogenetin
Gene namesi
Name:Ggn
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1306765. Ggn.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 658658GametogenetinPRO_0000239344Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei384 – 3841PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ66HC8.
PRIDEiQ66HC8.

Expressioni

Gene expression databases

GenevisibleiQ66HC8. RN.

Interactioni

Subunit structurei

Interacts with FANCL, GGNBP1 and ZNF403/GGNBP2.By similarity

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni127 – 491365Interaction with GGNBP1By similarityAdd
BLAST
Regioni496 – 658163Interactions with ZNF403/GGNBP2 and OAZ3By similarityAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi54 – 525472Pro-richAdd
BLAST
Compositional biasi566 – 5716Poly-Gly

Phylogenomic databases

eggNOGiENOG410IVS8. Eukaryota.
ENOG41115RQ. LUCA.
GeneTreeiENSGT00700000104635.
HOGENOMiHOG000112718.
HOVERGENiHBG081555.
InParanoidiQ66HC8.
OMAiRGLGVWF.
OrthoDBiEOG74FF17.
PhylomeDBiQ66HC8.

Family and domain databases

InterProiIPR031400. GGN.
[Graphical view]
PfamiPF15685. GGN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q66HC8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNVQSEPSA GGGSRKEQAS DRASDSRRTP LVEPEVTPSS PAMRLARGLG
60 70 80 90 100
VWFPGSSGPP GLLIPPESQA SSSTLPLTLE LPSPVTPPPE EAAAAAVSTP
110 120 130 140 150
PPPPVGTLLP APSKWRKPTG TAVPRIRGLL EASHRGQGDP PSLRPLPPLP
160 170 180 190 200
RQLTEKDPVL RAPAPPPTPL EPRKQLPPAP STCDPQPPSR RITLASSATS
210 220 230 240 250
PTESQVRHSS EGQAAGGAHG EGEMARSATS ESGLSLLCKV TFKSGPHLSP
260 270 280 290 300
TSSSGPLAAK ASLGASGGGG LFASSGAISY AEVLKQGPQP PGATRPLGEG
310 320 330 340 350
PRAAQETEGG DGDGEGCSGP PSVPTPLARA LPPPPYTTFP GSKPKFDWVS
360 370 380 390 400
PPDGTERHFR FNGAVGGIGA PRRRTTTLSG PWGSPPPRSG QTHPSSGPRR
410 420 430 440 450
PTPALLAPPM FIFPAPNNGE PVRPVPPSPQ QIPPLPPPPP TPPATPPPAP
460 470 480 490 500
PPTPQPPALP RTPILVARPP TPGPGHLESA LAPTPPSTLS PTAAAEQAPA
510 520 530 540 550
PTPAPVTSQV PATTTAELSP PMPQPKIRTR RNKGPRAARG VIREEGTSGD
560 570 580 590 600
GPREPNMAPV TDSSSGGGGG GSNGTSTAGA SNKGTARHWP PFEVLNSCPC
610 620 630 640 650
KCYCRHQRRH RRLPRNVSAW LSTPTNHLSE PPWVATVKLA GSLVAGLEHY

DLQATHST
Length:658
Mass (Da):67,501
Last modified:October 11, 2004 - v1
Checksum:iFEC8BBF003753046
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC081922 mRNA. Translation: AAH81922.1.
BC100147 mRNA. Translation: AAI00148.1.
RefSeqiNP_001013083.2. NM_001013065.1.
NP_001296756.1. NM_001309827.1.
XP_006228781.1. XM_006228719.2.
UniGeneiRn.52869.

Genome annotation databases

EnsembliENSRNOT00000056955; ENSRNOP00000053791; ENSRNOG00000023931.
GeneIDi292765.
KEGGirno:292765.
UCSCiRGD:1306765. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC081922 mRNA. Translation: AAH81922.1.
BC100147 mRNA. Translation: AAI00148.1.
RefSeqiNP_001013083.2. NM_001013065.1.
NP_001296756.1. NM_001309827.1.
XP_006228781.1. XM_006228719.2.
UniGeneiRn.52869.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiQ66HC8.
PRIDEiQ66HC8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000056955; ENSRNOP00000053791; ENSRNOG00000023931.
GeneIDi292765.
KEGGirno:292765.
UCSCiRGD:1306765. rat.

Organism-specific databases

CTDi199720.
RGDi1306765. Ggn.

Phylogenomic databases

eggNOGiENOG410IVS8. Eukaryota.
ENOG41115RQ. LUCA.
GeneTreeiENSGT00700000104635.
HOGENOMiHOG000112718.
HOVERGENiHBG081555.
InParanoidiQ66HC8.
OMAiRGLGVWF.
OrthoDBiEOG74FF17.
PhylomeDBiQ66HC8.

Miscellaneous databases

NextBioi634732.
PROiQ66HC8.

Gene expression databases

GenevisibleiQ66HC8. RN.

Family and domain databases

InterProiIPR031400. GGN.
[Graphical view]
PfamiPF15685. GGN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.
  2. "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues."
    Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C., Olsen J.V.
    Nat. Commun. 3:876-876(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-384, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiGGN_RAT
AccessioniPrimary (citable) accession number: Q66HC8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: October 11, 2004
Last modified: May 11, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.