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Protein
Submitted name:

Protein Tbp

Gene

Tbp

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-RNO-5250924. B-WICH complex positively regulates rRNA expression.
R-RNO-674695. RNA Polymerase II Pre-transcription Events.
R-RNO-6804756. Regulation of TP53 Activity through Phosphorylation.
R-RNO-6807505. RNA polymerase II transcribes snRNA genes.
R-RNO-73762. RNA Polymerase I Transcription Initiation.
R-RNO-73772. RNA Polymerase I Promoter Escape.
R-RNO-73776. RNA Polymerase II Promoter Escape.
R-RNO-73777. RNA Polymerase I Chain Elongation.
R-RNO-73779. RNA Polymerase II Transcription Pre-Initiation And Promoter Opening.
R-RNO-73863. RNA Polymerase I Transcription Termination.
R-RNO-75953. RNA Polymerase II Transcription Initiation.
R-RNO-76042. RNA Polymerase II Transcription Initiation And Promoter Clearance.
R-RNO-76061. RNA Polymerase III Transcription Initiation From Type 1 Promoter.
R-RNO-76066. RNA Polymerase III Transcription Initiation From Type 2 Promoter.
R-RNO-76071. RNA Polymerase III Transcription Initiation From Type 3 Promoter.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein TbpImported
Submitted name:
TATA box binding proteinImported
Submitted name:
TATA box binding protein, isoform CRA_aImported
Gene namesi
Name:TbpImported
ORF Names:rCG_22973Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi67398. Tbp.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: Ensembl
  • female pronucleus Source: Ensembl
  • male pronucleus Source: Ensembl
  • nuclear euchromatin Source: Ensembl
  • nucleus Source: RGD
  • transcription factor TFIIA complex Source: Ensembl
  • transcription factor TFIID complex Source: RGD
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSRNOG00000001489.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000002038.

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili49 – 72Sequence analysisAdd BLAST24

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3302. Eukaryota.
COG2101. LUCA.
GeneTreeiENSGT00410000025389.
HOGENOMiHOG000105164.
HOVERGENiHBG044997.
KOiK03120.
OMAiMMPYGSG.
OrthoDBiEOG091G0ENY.
TreeFamiTF300102.

Family and domain databases

CDDicd04516. TBP_eukaryotes. 1 hit.
Gene3Di3.30.310.10. 2 hits.
HAMAPiMF_00408. TATA_bind_prot_arch. 1 hit.
InterProiIPR012295. Beta2_adaptin/TBP_C_dom.
IPR000814. TBP.
IPR030491. TBP_CS.
IPR033710. TBP_eukaryotic.
[Graphical view]
PANTHERiPTHR10126. PTHR10126. 1 hit.
PfamiPF00352. TBP. 2 hits.
[Graphical view]
PRINTSiPR00686. TIFACTORIID.
PROSITEiPS00351. TFIID. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q66HB1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDQNNSLPPY AQGLASPQGA MTPGIPIFSP MMPYGTGLTP QPVQNTNSLS
60 70 80 90 100
ILEEQQRQQQ QQQQQQQQQQ QQAVATAAAS VQQSTSQQPT QGASGQTPQL
110 120 130 140 150
FHSQTLTTAP LPGTTPLYPS PMTPMTPITP ATPASESSGI VPQLQNIVST
160 170 180 190 200
VNLGCKLDLK TIALRARNAE YNPKRFAAVI MRIREPRTTA LIFSSGKMVC
210 220 230 240 250
TGAKSEEQSR LAARKYARVV QKLGFPAKFL DFKIQNMVGS CDVKFPIRLE
260 270 280 290 300
GLVLTHQQFS SYEPELFPGL IYRMIKPRIV LLIFVSGKVV LTGAKVRAEI
310
YEAFENIYPI LKGFRKTT
Length:318
Mass (Da):34,951
Last modified:October 11, 2004 - v1
Checksum:iDE52C057A2EEB6B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121701 Genomic DNA. No translation available.
BC081939 mRNA. Translation: AAH81939.1.
CH474033 Genomic DNA. Translation: EDL99816.1.
CH474033 Genomic DNA. Translation: EDL99817.1.
RefSeqiNP_001004198.1. NM_001004198.1.
XP_006228042.1. XM_006227980.3.
UniGeneiRn.22712.

Genome annotation databases

EnsembliENSRNOT00000002038; ENSRNOP00000002038; ENSRNOG00000001489.
GeneIDi117526.
KEGGirno:117526.
UCSCiRGD:67398. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121701 Genomic DNA. No translation available.
BC081939 mRNA. Translation: AAH81939.1.
CH474033 Genomic DNA. Translation: EDL99816.1.
CH474033 Genomic DNA. Translation: EDL99817.1.
RefSeqiNP_001004198.1. NM_001004198.1.
XP_006228042.1. XM_006227980.3.
UniGeneiRn.22712.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000002038.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000002038; ENSRNOP00000002038; ENSRNOG00000001489.
GeneIDi117526.
KEGGirno:117526.
UCSCiRGD:67398. rat.

Organism-specific databases

CTDi6908.
RGDi67398. Tbp.

Phylogenomic databases

eggNOGiKOG3302. Eukaryota.
COG2101. LUCA.
GeneTreeiENSGT00410000025389.
HOGENOMiHOG000105164.
HOVERGENiHBG044997.
KOiK03120.
OMAiMMPYGSG.
OrthoDBiEOG091G0ENY.
TreeFamiTF300102.

Enzyme and pathway databases

ReactomeiR-RNO-5250924. B-WICH complex positively regulates rRNA expression.
R-RNO-674695. RNA Polymerase II Pre-transcription Events.
R-RNO-6804756. Regulation of TP53 Activity through Phosphorylation.
R-RNO-6807505. RNA polymerase II transcribes snRNA genes.
R-RNO-73762. RNA Polymerase I Transcription Initiation.
R-RNO-73772. RNA Polymerase I Promoter Escape.
R-RNO-73776. RNA Polymerase II Promoter Escape.
R-RNO-73777. RNA Polymerase I Chain Elongation.
R-RNO-73779. RNA Polymerase II Transcription Pre-Initiation And Promoter Opening.
R-RNO-73863. RNA Polymerase I Transcription Termination.
R-RNO-75953. RNA Polymerase II Transcription Initiation.
R-RNO-76042. RNA Polymerase II Transcription Initiation And Promoter Clearance.
R-RNO-76061. RNA Polymerase III Transcription Initiation From Type 1 Promoter.
R-RNO-76066. RNA Polymerase III Transcription Initiation From Type 2 Promoter.
R-RNO-76071. RNA Polymerase III Transcription Initiation From Type 3 Promoter.

Gene expression databases

BgeeiENSRNOG00000001489.

Family and domain databases

CDDicd04516. TBP_eukaryotes. 1 hit.
Gene3Di3.30.310.10. 2 hits.
HAMAPiMF_00408. TATA_bind_prot_arch. 1 hit.
InterProiIPR012295. Beta2_adaptin/TBP_C_dom.
IPR000814. TBP.
IPR030491. TBP_CS.
IPR033710. TBP_eukaryotic.
[Graphical view]
PANTHERiPTHR10126. PTHR10126. 1 hit.
PfamiPF00352. TBP. 2 hits.
[Graphical view]
PRINTSiPR00686. TIFACTORIID.
PROSITEiPS00351. TFIID. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ66HB1_RAT
AccessioniPrimary (citable) accession number: Q66HB1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2004
Last sequence update: October 11, 2004
Last modified: November 30, 2016
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.