Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q66H90

- Q66H90_RAT

UniProt

Q66H90 - Q66H90_RAT

Protein
Submitted name:

Bardet-Biedl syndrome 7

Gene

Bbs7

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (11 Oct 2004)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Biological processi

    1. brain development Source: Ensembl
    2. eye development Source: Ensembl
    3. fat cell differentiation Source: Ensembl
    4. heart development Source: Ensembl
    5. limb development Source: Ensembl
    6. nonmotile primary cilium assembly Source: InterPro
    7. palate development Source: Ensembl
    8. positive regulation of proteasomal ubiquitin-dependent protein catabolic process Source: Ensembl
    9. protein localization Source: Ensembl
    10. regulation of transcription from RNA polymerase II promoter Source: Ensembl
    11. smoothened signaling pathway Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Bardet-Biedl syndrome 7Imported
    Submitted name:
    Protein Bbs7Imported
    Gene namesi
    Name:Bbs7Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 2

    Organism-specific databases

    RGDi1309264. Bbs7.

    Subcellular locationi

    GO - Cellular componenti

    1. BBSome Source: Ensembl
    2. centrosome Source: Ensembl

    Expressioni

    Gene expression databases

    GenevestigatoriQ66H90.

    Interactioni

    Protein-protein interaction databases

    STRINGi10116.ENSRNOP00000021453.

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG72192.
    GeneTreeiENSGT00390000012346.
    HOGENOMiHOG000022374.
    HOVERGENiHBG045408.
    InParanoidiQ66H90.
    KOiK16749.
    OMAiKPIHKWE.
    OrthoDBiEOG7CNZG6.
    TreeFamiTF315013.

    Family and domain databases

    Gene3Di2.130.10.10. 2 hits.
    InterProiIPR016575. Bardet-Biedl_syndrome_7_prot.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR017986. WD40_repeat_dom.
    [Graphical view]
    PIRSFiPIRSF011091. BBS7. 1 hit.
    SUPFAMiSSF50978. SSF50978. 2 hits.

    Sequencei

    Sequence statusi: Complete.

    Q66H90-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDLTLSRADY LQVGVTSQKT MKLLPTSRQR ATQKVVIGDQ DGVVMCFGMK    50
    KGEAVSVFKT LPGQKVSRLE LGGALNTPQE KIFIAAGSEI RGFTKRGKQF 100
    LSFETNLTES IKAMYISGSD LFLSASYIYN HYCDCKDQNY YLSGDKINDV 150
    ICLPVERLSR VTPVLACQDR VLRVLQGSDV TYEIEVPGPP TVLALHNGDG 200
    GDSGEGLLFG TSDGRLGLIQ ITASKPIHKW EIRNDKKRGG ILCLDSFDIM 250
    GDGVKDLLVG RDDGMVEVYS FENANEPVLR FDQMLSESVT SVQGGCVGKD 300
    GYDEIVLATY SGWVTGLTTE PTHKESGPGE ELKLNQEMQN KIASLRTELE 350
    HLQLKVLQER ENYQQSSQSS QAKSTVPSFS INDKFTLNKD DASYSLVLEV 400
    RTAIDNVLIQ SDVPIDLLDV DKNSAVVSFS SCDTESNDNF LLATYRCQAN 450
    TTRLELKIRS IEGQYGTLQA YVTPRIQPKT CQVRQYHIKP LSLHQRTHFI 500
    DHDRPMNTLT LTGQFSFAEV HSWAVLCLPE VPEKPPAGEC ATFYFQNTFL 550
    DTQLECAYRK GEGIFKSDNI STISILKDVL SKEATKRKIN LNISYEINEV 600
    SVKHTLKLIH PKLEYQLLLA KKVQLIDALK ELQVHEGNTS FLIPEYRCIL 650
    EEADHLQEEY KKQPAHLERL YGMITDLFID KFKFKGTNVK TKVPVLLEIL 700
    DSYDQNTLIS FFDAA 715
    Length:715
    Mass (Da):80,167
    Last modified:October 11, 2004 - v1
    Checksum:iEE83F5BAA263C278
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06015971 Genomic DNA. No translation available.
    BC081968 mRNA. Translation: AAH81968.1.
    RefSeqiNP_001012180.1. NM_001012180.1.
    UniGeneiRn.28442.

    Genome annotation databases

    EnsembliENSRNOT00000021453; ENSRNOP00000021453; ENSRNOG00000015816.
    GeneIDi361930.
    KEGGirno:361930.
    UCSCiRGD:1309264. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06015971 Genomic DNA. No translation available.
    BC081968 mRNA. Translation: AAH81968.1 .
    RefSeqi NP_001012180.1. NM_001012180.1.
    UniGenei Rn.28442.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10116.ENSRNOP00000021453.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000021453 ; ENSRNOP00000021453 ; ENSRNOG00000015816 .
    GeneIDi 361930.
    KEGGi rno:361930.
    UCSCi RGD:1309264. rat.

    Organism-specific databases

    CTDi 55212.
    RGDi 1309264. Bbs7.

    Phylogenomic databases

    eggNOGi NOG72192.
    GeneTreei ENSGT00390000012346.
    HOGENOMi HOG000022374.
    HOVERGENi HBG045408.
    InParanoidi Q66H90.
    KOi K16749.
    OMAi KPIHKWE.
    OrthoDBi EOG7CNZG6.
    TreeFami TF315013.

    Miscellaneous databases

    NextBioi 678090.
    PROi Q66H90.

    Gene expression databases

    Genevestigatori Q66H90.

    Family and domain databases

    Gene3Di 2.130.10.10. 2 hits.
    InterProi IPR016575. Bardet-Biedl_syndrome_7_prot.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR017986. WD40_repeat_dom.
    [Graphical view ]
    PIRSFi PIRSF011091. BBS7. 1 hit.
    SUPFAMi SSF50978. SSF50978. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: LungImported.
    2. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiQ66H90_RAT
    AccessioniPrimary (citable) accession number: Q66H90
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2004
    Last sequence update: October 11, 2004
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3