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Protein

Protein FAM71B

Gene

Fam71b

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

May be involved in RNA biogenesis.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM71B
Gene namesi
Name:Fam71b
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1563555. Fam71b.

Subcellular locationi

  • Nucleus

  • Note: Cajal body and speckle localization.By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 647647Protein FAM71BPRO_0000285645Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei378 – 3781PhosphoserineCombined sources
Modified residuei634 – 6341PhosphoserineCombined sources
Modified residuei636 – 6361PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ66H38.
PRIDEiQ66H38.

PTM databases

iPTMnetiQ66H38.
PhosphoSiteiQ66H38.

Expressioni

Gene expression databases

BgeeiENSRNOG00000021425.

Interactioni

Subunit structurei

Interacts with FRG1.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ66H38.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi494 – 51118Bipartite nuclear localization signalSequence analysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi224 – 343120Ala-richAdd
BLAST

Sequence similaritiesi

Belongs to the FAM71 family.Curated

Phylogenomic databases

eggNOGiENOG410IH8C. Eukaryota.
ENOG410YQV3. LUCA.
HOGENOMiHOG000290696.
HOVERGENiHBG058004.
InParanoidiQ66H38.
OrthoDBiEOG091G0EE4.
PhylomeDBiQ66H38.

Family and domain databases

InterProiIPR022168. DUF3699.
IPR000048. IQ_motif_EF-hand-BS.
[Graphical view]
PfamiPF12480. DUF3699. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q66H38-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSECLLPYY TAHSYRSMGV FNTSMGNLQR QLYKGGEYDI FKYAPMFESD
60 70 80 90 100
FIQISKKGEV IDVHNRVRMV TVCIASTSPV LPLPDVMLLA RPAKVCEEHA
110 120 130 140 150
RRARFIKGRG YKPSKTLELT RLLPLKFVKI SIHDHEKQQL RLKLATGRTF
160 170 180 190 200
YLQLCPSSDA REDLFCYWEK LVYLLRPPVN SCISNPSIPT ADTSTETKST
210 220 230 240 250
LVSEIHGEGD RDSKFQTSQD VSEATSAAFA GGERTQPNIA AILTTGLAKA
260 270 280 290 300
RAAGAAAGTG AAGTAGTAGA AGATGAAGAT GAAGSARAAG GAGSARAAGA
310 320 330 340 350
TGSARAAGAT GSARAAGATG SARAAGGNTA AAVMTPLAGL ARAGTPTSPV
360 370 380 390 400
SGVISIAATT SKSPGSGQVA TGLTGTASKD QERSESSKAM AVVANITTES
410 420 430 440 450
VDVVLAGAAS FTSESPSAEG DAYGSPDTGL NVAFAGSITT KGPAEDKPEA
460 470 480 490 500
PLVSTLQSEG YMCERDGSQK VSHTSSETQK EKRERRESDR KGSRKSSHHQ
510 520 530 540 550
RTGASRHSSS KDKGRKTSSY RSVSGHGKTR EDKKEKGRGS LRDQRHSSSY
560 570 580 590 600
RSESRTGHKS RKNRPAASGG FVSKRATKIR SFFRAFLVRP TLKTENTSGE
610 620 630 640
RGGVDIVTKL VEKQDIETTV EKSKDLEFSD TMASESMEKI ILETKPI
Length:647
Mass (Da):68,071
Last modified:October 11, 2004 - v1
Checksum:iB04129C913FA9B06
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC082044 mRNA. Translation: AAH82044.1.
RefSeqiNP_001020202.2. NM_001025031.1.
UniGeneiRn.122734.

Genome annotation databases

GeneIDi497888.
KEGGirno:497888.
UCSCiRGD:1563555. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC082044 mRNA. Translation: AAH82044.1.
RefSeqiNP_001020202.2. NM_001025031.1.
UniGeneiRn.122734.

3D structure databases

ProteinModelPortaliQ66H38.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiQ66H38.
PhosphoSiteiQ66H38.

Proteomic databases

PaxDbiQ66H38.
PRIDEiQ66H38.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi497888.
KEGGirno:497888.
UCSCiRGD:1563555. rat.

Organism-specific databases

CTDi153745.
RGDi1563555. Fam71b.

Phylogenomic databases

eggNOGiENOG410IH8C. Eukaryota.
ENOG410YQV3. LUCA.
HOGENOMiHOG000290696.
HOVERGENiHBG058004.
InParanoidiQ66H38.
OrthoDBiEOG091G0EE4.
PhylomeDBiQ66H38.

Miscellaneous databases

PROiQ66H38.

Gene expression databases

BgeeiENSRNOG00000021425.

Family and domain databases

InterProiIPR022168. DUF3699.
IPR000048. IQ_motif_EF-hand-BS.
[Graphical view]
PfamiPF12480. DUF3699. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFA71B_RAT
AccessioniPrimary (citable) accession number: Q66H38
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: October 11, 2004
Last modified: September 7, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.