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Protein

Probable G-protein coupled receptor 160

Gene

Gpr160

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Orphan receptor.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
Probable G-protein coupled receptor 160
Gene namesi
Name:Gpr160
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi1560200. Gpr160.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2121ExtracellularSequence analysisAdd
BLAST
Transmembranei22 – 4221Helical; Name=1Sequence analysisAdd
BLAST
Topological domaini43 – 5614CytoplasmicSequence analysisAdd
BLAST
Transmembranei57 – 7721Helical; Name=2Sequence analysisAdd
BLAST
Topological domaini78 – 9518ExtracellularSequence analysisAdd
BLAST
Transmembranei96 – 11621Helical; Name=3Sequence analysisAdd
BLAST
Topological domaini117 – 13620CytoplasmicSequence analysisAdd
BLAST
Transmembranei137 – 15721Helical; Name=4Sequence analysisAdd
BLAST
Topological domaini158 – 18730ExtracellularSequence analysisAdd
BLAST
Transmembranei188 – 20821Helical; Name=5Sequence analysisAdd
BLAST
Topological domaini209 – 24335CytoplasmicSequence analysisAdd
BLAST
Transmembranei244 – 26421Helical; Name=6Sequence analysisAdd
BLAST
Topological domaini265 – 2728ExtracellularSequence analysis
Transmembranei273 – 29321Helical; Name=7Sequence analysisAdd
BLAST
Topological domaini294 – 33643CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 336336Probable G-protein coupled receptor 160PRO_0000069645Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi8 – 81N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ66H29.
PRIDEiQ66H29.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000012560.

Structurei

3D structure databases

ProteinModelPortaliQ66H29.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IK2K. Eukaryota.
ENOG410YX66. LUCA.
GeneTreeiENSGT00390000015520.
HOGENOMiHOG000112776.
HOVERGENiHBG062414.
InParanoidiQ66H29.
KOiK08438.
OMAiEMNVPWL.
OrthoDBiEOG72G17T.
PhylomeDBiQ66H29.
TreeFamiTF335541.

Family and domain databases

InterProiIPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q66H29-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTALPSKNCS FQYQSHQAPR SLDATCLLLL IILGKVLLNV LILRVKRKDT
60 70 80 90 100
SWSFMEYFCF SLALVDLLLL VNISVLTYFR DFVVLGIRFT NYHICLLTQI
110 120 130 140 150
VSFAYGFLHY PVCSLACIDY WCNLSRATKP SSRWQKLLYL LTVILTWISV
160 170 180 190 200
LAYVLGDPAI SASLKTHKTS VNQCPSYVST QSHWLSLSML MILSVAFLIS
210 220 230 240 250
WQEVVALIQA IRIASYKNKA VLYFPFPPHT SYTVSPRAVL LPRLIVCFLG
260 270 280 290 300
TWFPFVALQV LILSLRVQIP AYIEMNVPWL YFVNSFLIAA VYWFNCHKLY
310 320 330
WRDGMFPVDP FINWKCCFVP VHRLKQVERP MSIIIC
Length:336
Mass (Da):38,783
Last modified:October 11, 2004 - v1
Checksum:i6A4F7ECC6C3EDC4D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC082060 mRNA. Translation: AAH82060.1.
RefSeqiNP_001020318.1. NM_001025147.1.
XP_008759157.1. XM_008760935.1.
XP_008759158.1. XM_008760936.1.
UniGeneiRn.139484.

Genome annotation databases

EnsembliENSRNOT00000012560; ENSRNOP00000012560; ENSRNOG00000009487.
GeneIDi499588.
KEGGirno:499588.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC082060 mRNA. Translation: AAH82060.1.
RefSeqiNP_001020318.1. NM_001025147.1.
XP_008759157.1. XM_008760935.1.
XP_008759158.1. XM_008760936.1.
UniGeneiRn.139484.

3D structure databases

ProteinModelPortaliQ66H29.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000012560.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiQ66H29.
PRIDEiQ66H29.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000012560; ENSRNOP00000012560; ENSRNOG00000009487.
GeneIDi499588.
KEGGirno:499588.

Organism-specific databases

CTDi26996.
RGDi1560200. Gpr160.

Phylogenomic databases

eggNOGiENOG410IK2K. Eukaryota.
ENOG410YX66. LUCA.
GeneTreeiENSGT00390000015520.
HOGENOMiHOG000112776.
HOVERGENiHBG062414.
InParanoidiQ66H29.
KOiK08438.
OMAiEMNVPWL.
OrthoDBiEOG72G17T.
PhylomeDBiQ66H29.
TreeFamiTF335541.

Miscellaneous databases

NextBioi703361.
PROiQ66H29.

Family and domain databases

InterProiIPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.

Entry informationi

Entry nameiGP160_RAT
AccessioniPrimary (citable) accession number: Q66H29
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: October 11, 2004
Last modified: November 11, 2015
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.