Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q66GE5

- KGUA_YERPS

UniProt

Q66GE5 - KGUA_YERPS

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Guanylate kinase

Gene

gmk

Organism
Yersinia pseudotuberculosis serotype I (strain IP32953)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi11 – 188ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. guanylate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. purine nucleotide metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYPSE273123:GI1M-43-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:YPTB0037
OrganismiYersinia pseudotuberculosis serotype I (strain IP32953)
Taxonomic identifieri273123 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000001011: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 207207Guanylate kinasePRO_0000170648Add
BLAST

Proteomic databases

PRIDEiQ66GE5.

Interactioni

Protein-protein interaction databases

STRINGi273123.YPTB0037.

Structurei

3D structure databases

ProteinModelPortaliQ66GE5.
SMRiQ66GE5. Positions 3-207.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 184181Guanylate kinase-likeUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation
Contains 1 guanylate kinase-like domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG0194.
HOGENOMiHOG000037638.
KOiK00942.
OMAiMSHYNEY.
OrthoDBiEOG6CP410.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00328. Guanylate_kinase.
InterProiIPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00625. Guanylate_kin. 1 hit.
[Graphical view]
SMARTiSM00072. GuKc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q66GE5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVQGTLYIVS APSGAGKSSL IQALLKTQPL YDTQVSISHT TRAKRPGENH
60 70 80 90 100
GEHYFFVSEK EFCQMIDDDA FLEHAKVFEN YYGTSRLAIE QVLATGVDVF
110 120 130 140 150
LDIDWQGAQQ IRAKMPTARS IFILPPSKTE LDRRLRGRGQ DSEEVIAKRM
160 170 180 190 200
EQAVAEMAHY AEYDYLIVND DFNLALSDLK TIIRAERLRL GRQKQRHDAL

ISKLLAD
Length:207
Mass (Da):23,504
Last modified:October 11, 2004 - v1
Checksum:i01FDCD618EFED91E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX936398 Genomic DNA. Translation: CAH19277.1.
RefSeqiYP_068586.1. NC_006155.1.

Genome annotation databases

EnsemblBacteriaiCAH19277; CAH19277; YPTB0037.
GeneIDi2955731.
KEGGiyps:YPTB0037.
PATRICi18638110. VBIYerPse22266_0178.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX936398 Genomic DNA. Translation: CAH19277.1 .
RefSeqi YP_068586.1. NC_006155.1.

3D structure databases

ProteinModelPortali Q66GE5.
SMRi Q66GE5. Positions 3-207.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273123.YPTB0037.

Proteomic databases

PRIDEi Q66GE5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAH19277 ; CAH19277 ; YPTB0037 .
GeneIDi 2955731.
KEGGi yps:YPTB0037.
PATRICi 18638110. VBIYerPse22266_0178.

Phylogenomic databases

eggNOGi COG0194.
HOGENOMi HOG000037638.
KOi K00942.
OMAi MSHYNEY.
OrthoDBi EOG6CP410.

Enzyme and pathway databases

BioCyci YPSE273123:GI1M-43-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 2 hits.
HAMAPi MF_00328. Guanylate_kinase.
InterProi IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF00625. Guanylate_kin. 1 hit.
[Graphical view ]
SMARTi SM00072. GuKc. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR03263. guanyl_kin. 1 hit.
PROSITEi PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IP32953.

Entry informationi

Entry nameiKGUA_YERPS
AccessioniPrimary (citable) accession number: Q66GE5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: October 11, 2004
Last modified: October 29, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3