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Q66ED7

- Q66ED7_YERPS

UniProt

Q66ED7 - Q66ED7_YERPS

Protein

Superoxide dismutase [Cu-Zn]

Gene

sodC

Organism
Yersinia pseudotuberculosis serotype I (strain IP32953)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 1 (11 Oct 2004)
      Previous versions | rss
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    Functioni

    Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

    Catalytic activityi

    2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

    Cofactori

    Binds 1 copper ion per subunit.UniRule annotation
    Binds 1 zinc ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi26 – 261Zinc 1Imported
    Metal bindingi27 – 271Zinc 1Imported
    Metal bindingi82 – 821Zinc 2; via pros nitrogenImported
    Metal bindingi84 – 841Zinc 2; via tele nitrogenImported
    Metal bindingi107 – 1071Zinc 2; via tele nitrogenImported
    Metal bindingi107 – 1071Zinc 3; via pros nitrogenImported
    Metal bindingi116 – 1161Zinc 3; via pros nitrogenImported
    Metal bindingi125 – 1251Zinc 3; via pros nitrogenImported
    Metal bindingi128 – 1281Zinc 3Imported
    Metal bindingi163 – 1631Zinc 2; via tele nitrogenImported

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. superoxide dismutase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotationImported

    Keywords - Ligandi

    CopperUniRule annotation, Metal-bindingUniRule annotationImported, ZincUniRule annotationImported

    Enzyme and pathway databases

    BioCyciYPSE273123:GI1M-797-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
    Gene namesi
    Name:sodCImported
    Ordered Locus Names:YPTB0756Imported
    OrganismiYersinia pseudotuberculosis serotype I (strain IP32953)Imported
    Taxonomic identifieri273123 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000001011: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2020 PotentialImportedAdd
    BLAST
    Chaini21 – 189169 PotentialImportedPRO_5000098466Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi273123.YPTB0756.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2WWNX-ray2.60A/B21-189[»]
    2WWOX-ray2.40A/B21-189[»]
    ProteinModelPortaliQ66ED7.
    SMRiQ66ED7. Positions 36-189.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ66ED7.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

    Keywords - Domaini

    SignalImported

    Phylogenomic databases

    HOGENOMiHOG000263449.
    KOiK04565.
    OMAiITETPYG.
    OrthoDBiEOG6K13RS.

    Family and domain databases

    Gene3Di2.60.40.200. 1 hit.
    InterProiIPR018152. SOD_Cu/Zn_BS.
    IPR001424. SOD_Cu_Zn_dom.
    [Graphical view]
    PfamiPF00080. Sod_Cu. 1 hit.
    [Graphical view]
    SUPFAMiSSF49329. SSF49329. 1 hit.
    PROSITEiPS00087. SOD_CU_ZN_1. 1 hit.
    PS00332. SOD_CU_ZN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q66ED7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKLSTLLLPV ILYSSATLAA NMAGMNDKAS MNDKASMTVK INESLPQGNG    50
    KALGTVTVTE TAYGLLFTPH LTGLAPGIHG FHLHEKPSCA PGMKDGKAVP 100
    ALAAGGHLDP NKTGVHLGPY NDKGHLGDLP GLVVNADGTA TYPVLAPRLK 150
    SLSEVKQHAL MIHAGGDNYS DHPMPLGGGG ARMACGVIE 189
    Length:189
    Mass (Da):19,436
    Last modified:October 11, 2004 - v1
    Checksum:i9E996703B09163E0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX936398 Genomic DNA. Translation: CAH19996.1.
    RefSeqiYP_069297.1. NC_006155.1.

    Genome annotation databases

    EnsemblBacteriaiCAH19996; CAH19996; YPTB0756.
    GeneIDi2956620.
    KEGGiyps:YPTB0756.
    PATRICi18639806. VBIYerPse22266_0996.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX936398 Genomic DNA. Translation: CAH19996.1 .
    RefSeqi YP_069297.1. NC_006155.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2WWN X-ray 2.60 A/B 21-189 [» ]
    2WWO X-ray 2.40 A/B 21-189 [» ]
    ProteinModelPortali Q66ED7.
    SMRi Q66ED7. Positions 36-189.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 273123.YPTB0756.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAH19996 ; CAH19996 ; YPTB0756 .
    GeneIDi 2956620.
    KEGGi yps:YPTB0756.
    PATRICi 18639806. VBIYerPse22266_0996.

    Phylogenomic databases

    HOGENOMi HOG000263449.
    KOi K04565.
    OMAi ITETPYG.
    OrthoDBi EOG6K13RS.

    Enzyme and pathway databases

    BioCyci YPSE273123:GI1M-797-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei Q66ED7.

    Family and domain databases

    Gene3Di 2.60.40.200. 1 hit.
    InterProi IPR018152. SOD_Cu/Zn_BS.
    IPR001424. SOD_Cu_Zn_dom.
    [Graphical view ]
    Pfami PF00080. Sod_Cu. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49329. SSF49329. 1 hit.
    PROSITEi PS00087. SOD_CU_ZN_1. 1 hit.
    PS00332. SOD_CU_ZN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: IP32953Imported.
    2. "Crystal Structure of the Yersinia Pseudotuberculosis Superoxide Dismutase (Sodc)."
      Huyet J., Naylor C.E., Titball R.W., Bullifent H., Walker N., Jones H.E., Duffied M.L., Basak A.K.
      Submitted (OCT-2009) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 21-189 IN COMPLEX WITH ZINC.

    Entry informationi

    Entry nameiQ66ED7_YERPS
    AccessioniPrimary (citable) accession number: Q66ED7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2004
    Last sequence update: October 11, 2004
    Last modified: October 1, 2014
    This is version 85 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteomeImported

    External Data

    Dasty 3