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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Yersinia pseudotuberculosis serotype I (strain IP32953)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei67L-glutamineUniRule annotation1
Binding sitei212L-glutamineUniRule annotation1
Binding sitei231ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi35 – 37ATPUniRule annotation3
Nucleotide bindingi41 – 47ATPUniRule annotation7
Nucleotide bindingi261 – 262ATPUniRule annotation2
Nucleotide bindingi269 – 271ATPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Short name:
GlnRSUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:YPTB1121
OrganismiYersinia pseudotuberculosis serotype I (strain IP32953)
Taxonomic identifieri273123 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000001011 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002428841 – 555Glutamine--tRNA ligaseAdd BLAST555

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ66DC5
SMRiQ66DC5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi34 – 44"HIGH" regionUniRule annotationAdd BLAST11
Motifi268 – 272"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000259232
KOiK01886
OMAiVTHSICT

Family and domain databases

Gene3Di1.10.1160.101 hit
2.40.240.102 hits
3.40.50.6202 hits
HAMAPiMF_00126 Gln_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR004514 Gln-tRNA-synth
IPR022861 Gln_tRNA_ligase_bac
IPR000924 Glu/Gln-tRNA-synth
IPR020058 Glu/Gln-tRNA-synth_Ib_cat-dom
IPR020059 Glu/Gln-tRNA-synth_Ib_codon-bd
IPR020061 Glu_tRNA_lig_a-bdl
IPR020056 Rbsml_L25/Gln-tRNA_synth_N
IPR011035 Ribosomal_L25/Gln-tRNA_synth
IPR014729 Rossmann-like_a/b/a_fold
PfamiView protein in Pfam
PF00749 tRNA-synt_1c, 1 hit
PF03950 tRNA-synt_1c_C, 1 hit
PRINTSiPR00987 TRNASYNTHGLU
SUPFAMiSSF50715 SSF50715, 1 hit
TIGRFAMsiTIGR00440 glnS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q66DC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEAEARPSN FIRQIIDEDL ASGKHTSVHT RFPPEPNGYL HIGHAKSICL
60 70 80 90 100
NFGIAEDYQG QCNLRFDDTN PVKEDVEFVE SIKRDVEWLG FTWSGDVRYS
110 120 130 140 150
SDYFDQLYQY AVELINKGLA YVDELTPEQM REYRGTLTAP GKNSPYRDRS
160 170 180 190 200
VEENLALFEK MRAGGFAEGT ACLRAKIDMA SPFIVMRDPV LYRIKFAEHH
210 220 230 240 250
QSGNKWCIYP MYDFTHCISD ALEGITHSLC TLEFQDNRRL YDWVLDNISI
260 270 280 290 300
DCHPRQYEFS RLNLEYTIMS KRKLNQLVTE KVVEGWDDPR MPTISGLRRR
310 320 330 340 350
GYTAASIREF CRRIGVTKQD NNVEMMSLES CIRDDLNEHA PRAMAVLDPI
360 370 380 390 400
KVVIENRAAG EEWLTMPNHP NNPEMGSRQV PFDSEIYIDR ADFREEANKQ
410 420 430 440 450
YKRLVLGKEV RLRNAYVIKA ERVEKDAEGN VTTLYCSYDA ETLNKDPADG
460 470 480 490 500
RKVKGVIHWV SVAHALPAEI RLYDRLFNVP NPAAAEDFLS TINPESLVIR
510 520 530 540 550
QGFVEPSLAD AVSDKTYQFE REGYFCADSR YSRPGALVFN RTVGLRDTWA

AKATQ
Length:555
Mass (Da):63,751
Last modified:October 11, 2004 - v1
Checksum:iAD3C68D6FB56C0B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX936398 Genomic DNA Translation: CAH20361.1
RefSeqiWP_002210354.1, NZ_CP009712.1

Genome annotation databases

EnsemblBacteriaiCAH20361; CAH20361; YPTB1121
KEGGiypo:BZ17_1416
yps:YPTB1121
PATRICifig|273123.14.peg.1504

Similar proteinsi

Entry informationi

Entry nameiSYQ_YERPS
AccessioniPrimary (citable) accession number: Q66DC5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: October 11, 2004
Last modified: February 28, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome