Reviewed, UniProtKB/Swiss-Prot Q66CS8 (RPIA2_YERPS)

Names and origin

Protein names

Recommended name:
    Ribose-5-phosphate isomerase A 2
    EC=5.3.1.6
Alternative name(s):
    Phosphoriboisomerase A 2
      Short name=PRI 2

Gene names

Name:	rpiA2
Ordered Locus Names:	YPTB1324

Organism

Yersinia pseudotuberculosis [Complete proteome] [HAMAP]

Taxonomic identifier

633 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia

Protein attributes

Sequence length	236 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: HAMAP
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 236	236	Ribose-5-phosphate isomerase A 2 HAMAP MF_00170		PRO_0000158504

Sequences

	Sequence		Length	Mass (Da)
	Q66CS8-1 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 2E1D870A15A044FA	FASTA	236	26,034
	10 20 30 40 50 60 MSNQQNDAKR AAARRVIQDF VFDGMTLGLG SGTTSHFFVR ELGQHVAKGL QLTCTTTSRA 70 80 90 100 110 120 TSEVARDVGI ELSDPNEMNE IDLTIDGPDE IDRRFNMIKG GGACLLWEKI IAHASKRMIC 130 140 150 160 170 180 ICDETKIVNC LGQFPLPVEI VPFAWKQTER RVERVLAEQG LHHVPIIRRM GGGHPVITDS 190 200 210 220 230 GNFILDCHCG AIITAPEPLE IELNRIPGVV ENGLFTREAT GMVVGYFDGS SYVQLR

References

[1]

"Insights into the evolution of Yersinia pestis through whole-genome comparison with Yersinia pseudotuberculosis." Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O., Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L., Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C., Simonet M., Chenal-Francisque V., Souza B. , Dacheux D., Elliott J.M., Derbise A., Hauser L.J., Garcia E. Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004) [PubMed: 15358858] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IP32953 / Serotype I.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX936398 Genomic DNA. Translation: CAH20564.1.
RefSeq	YP_069856.1.
3D structure databases
SMR	Q66CS8. Positions 5-231.
ModBase	Search...
Genome annotation databases
GeneID	2956484.
GenomeReviews	Gene locus YPTB1324 in contig BX936398_GR.
KEGG	yps:YPTB1324.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG515603.
OMA	VENGLFI.
Enzyme and pathway databases
BioCyc	YPSE273123:YPTB1324-MONOMER.
BRENDA	5.3.1.6. 20871.
Family and domain databases
HAMAP	MF_00170. Rib_5P_isom_A. [Tree]
InterPro	IPR004788. Ribose5P_isomerase_typA. IPR020672. Ribose5P_isomerase_typA_subgr. [Graphical view]
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. rpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA2_YERPS

Accession

Primary (citable) accession number: Q66CS8

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 7, 2005
Last sequence update:	October 11, 2004
Last modified:	February 9, 2010
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)