Q66AF7 (ARAB_YERPS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribulokinase
EC=2.7.1.16

Gene names

Name:	araB
Ordered Locus Names:	YPTB2173

Organism

Yersinia pseudotuberculosis [Complete proteome] [HAMAP]

Taxonomic identifier

633 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia

Protein attributes

Sequence length	563 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate. HAMAP MF_00520
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 2/3. HAMAP MF_00520
Sequence similarities	Belongs to the ribulokinase family.
Sequence caution	The sequence CAH21411.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	L-arabinose catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ribulokinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 563	563	Ribulokinase HAMAP MF_00520		PRO_0000198378

Sequences

	Sequence		Length	Mass (Da)
	Q66AF7 [UniParc]. Last modified March 1, 2005. Version 2. Checksum: B9FF9495BAD83DE4	FASTA	563	61,766
	10 20 30 40 50 60 MISADGAIAL GLDFGSDSVR VLAVDCQHGT EIDTEVVYYP RWKKGLYCQA AQNQFRHHPL 70 80 90 100 110 120 DYIEAMEQAI RQMVKRLSEE QRQHIVGIGV DSTGSTPAPI DEQGQVLALR PDFADNPNAM 130 140 150 160 170 180 FVLWKDHTAI EEAEEINRLC RSGEFADYSR YIGGVYSSEW FWAKILHVTR ADVAVREAAV 190 200 210 220 230 240 SWIELCDWVP ALLSGTTAPQ DIQRGRCSAG HKSLWHPSWG GLPPRAFLAA LDTSLVNDLD 250 260 270 280 290 300 YPMFTDTYTA ERPVGQITAE WAERLGLPTT VILSGGAFDC HMGAVGAGAQ PYTLVKVIGT 310 320 330 340 350 360 STCDILIADD QRVGDRAIAG ICGQVEGSVL PGWIGMEAGQ SAFGDMYAWF SNLLSWPLHQ 370 380 390 400 410 420 AALTQPEWQP QLKQIESNLL ASLTCAWAQN PSLDHLPVVL DWFNGRRTPN ANQRLKGVIT 430 440 450 460 470 480 DLNLGTDAPT LFGGFIAATA FGARAIMECF EQQDIPVENV LALGGIARKS PVIMQVCADV 490 500 510 520 530 540 MNRPLQIVAS DQCCALGAAI FAAVAAGAHE DVPTAQRHMA CNIERTLIPD PVQVVRYQQL 550 560 YQRYQQWCHT AEPHYAPVTK AIH

References

[1]

"Insights into the evolution of Yersinia pestis through whole-genome comparison with Yersinia pseudotuberculosis." Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O., Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L., Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C., Simonet M., Chenal-Francisque V., Souza B. , Dacheux D., Elliott J.M., Derbise A., Hauser L.J., Garcia E. Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004) [PubMed: 15358858] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IP32953 / Serotype I.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX936398 Genomic DNA. Translation: CAH21411.1. Different initiation.
RefSeq	YP_070690.1. NC_006155.1.
3D structure databases
ProteinModelPortal	Q66AF7.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2955203.
GenomeReviews	Gene locus YPTB2173 in contig BX936398_GR.
KEGG	yps:YPTB2173.
NMPDR	fig|273123.1.peg.2272.
PATRIC	18643208. VBIYerPse22266_2662.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG312681.
OMA	NGRRTPD.
ProtClustDB	PRK04123.
Enzyme and pathway databases
BioCyc	YPSE273123:YPTB2173-MONOMER.
Family and domain databases
HAMAP	MF_00520. Ribulokinase. [Tree]
InterPro	IPR000577. Carb_kinase_FGGY. IPR018485. Carb_kinase_FGGY_C. IPR018484. Carb_kinase_FGGY_N. IPR005929. L_ribulokin. [Graphical view]
KO	K00853.
PANTHER	PTHR10196. FGGY_kin. 1 hit.
Pfam	PF02782. FGGY_C. 1 hit. PF00370. FGGY_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR01234. L-ribulokinase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARAB_YERPS

Accession

Primary (citable) accession number: Q66AF7

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 2005
Last sequence update:	March 1, 2005
Last modified:	January 25, 2012
This is version 43 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program