Q66A79 (Q66A79_YERPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Pyruvate-flavodoxin oxidoreductase PIRNR PIRNR000159
EC=1.2.7.- PIRNR PIRNR000159

Gene names

Name:	nifJ EMBL CAH21491.1
Ordered Locus Names:	YPTB2253 EMBL CAH21491.1

Organism

Yersinia pseudotuberculosis serotype I (strain IP32953) [Complete proteome] [HAMAP] EMBL CAH21491.1

Taxonomic identifier

273123 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia › Yersinia pseudotuberculosis

Protein attributes

Sequence length	1177 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin By similarity. PIRNR PIRNR000159
Catalytic activity	Pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin. PIRNR PIRNR000159
Sequence similarities	Belongs to the nifJ family. PIRNR PIRNR000159

Ontologies

Keywords
Biological process	Electron transport PIRNR PIRNR000159 Transport
Ligand	Pyruvate EMBL CAH21491.1
Molecular function	Oxidoreductase PIRNR PIRNR000159 EMBL CAH21491.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	electron carrier activity Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro iron-sulfur cluster binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the aldehyde or oxo group of donors Inferred from electronic annotation. Source: InterPro thiamine pyrophosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q66A79 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: ABD21DB2C2F99CB3	FASTA	1,177	129,512
	10 20 30 40 50 60 MITTDGNSAV ASVAYRASEV IAIYPITPSS TMAEQADAWS GDGKVNIWGD VPRVVEMQSE 70 80 90 100 110 120 GGAIATVHGA LQTGALSTSF TSSQGLLLMI PTLYKLAGEL TPFVLHVAAR TIATHALSIF 130 140 150 160 170 180 GDHSDVMAVR QTGCAMLCAS SVQEAQDFAL ISQIATLNSR IPFIHFFDGF RTSHEINKIE 190 200 210 220 230 240 PLSDETLRQL LPQAGINAHR SRALSPDHPV VRGTSANPDT YFQSREATNP WYNNTYQHVA 250 260 270 280 290 300 DAMQAFAEAT GREYKPFEYY GHPQADRVII LMGSAIGTCE EVIDTLLTRG EKVGVLKVRL 310 320 330 340 350 360 FRPFSAQHLL ALLPASVGKI AVLDRTKEPG ALAEPLYLDV MTALAEAYSR GDRDTLPKVI 370 380 390 400 410 420 GGRYGLSSKE FGPHCVLAIF RELSLDLPRP RFTVGIFDDV TGLSLPLSDE KIESRATLEA 430 440 450 460 470 480 LFYGLGSDGS VSATKNNIKI IGNSTALYAQ GYFVYDSKKA GGLTVSHLRV SQTPINSAYL 490 500 510 520 530 540 VSHADFVGCH QLQFIDIYQM AERLKPGGIF LLNTPFSADE MWPRLPQDVQ AVLHQRHARL 550 560 570 580 590 600 FVINAAKIAR ECKLGARINT VMQMAFFHLT QILPTAMAQE QLRAAIERSY SNKGAEIVTR 610 620 630 640 650 660 NWQALDATLE ALIEIPLQPI DENSPVRPPI VSDQAPDFVK TVTATMLAGL GDTLPVSAFP 670 680 690 700 710 720 PDGTWPVGTT QWEKRNIAEN IPIWQPDLCT QCNHCVAACP HSAIRAKVVQ PEAMAGAPDS 730 740 750 760 770 780 LQSLDVKARD MRGQKYVLQV APEDCTGCNL CYEVCPAKDR QNPEIKAINM RPRLEHRAVE 790 800 810 820 830 840 KAHYDFFLKL PEIDKTQMER IDIRTSQLIS PLFEYSGACS GCGETPYIKL LTQLYGDRLL 850 860 870 880 890 900 IANATGCSSI YGGNLPTTPY TTNADGRGPA WANSLFEDNA EFGLGFRLTV DQHQKRVTRL 910 920 930 940 950 960 IQQLAPQLPD ELVNQLINQE YTPEERRKQV SQLRQLLREI PGNDAQQLAA DADYLVDKSI 970 980 990 1000 1010 1020 WLIGGDGWAY DIGFGGLDHV LSLTENVNVL VLDTQCYSNT GGQQSKATPL GAVTKFGEHG 1030 1040 1050 1060 1070 1080 KRKARKDLGV SMMMYGHVYV AQISIGAQLN QTVKAIQEAE AYPGPSLIIA YSPCEEHGYD 1090 1100 1110 1120 1130 1140 LAYSHDQMKQ LTATGFWPLY RFDPRRADEG KTALALDSRP PSSDLTTTLL NEQRFRRLNT 1150 1160 1170 QEPAVAAQLY AEAEKDLKKR YDFLSLLAGK TEKTPSE

References

[1]

"Insights into the evolution of Yersinia pestis through whole-genome comparison with Yersinia pseudotuberculosis." Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O., Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin L.V., Brubaker R.R., Fowler J., Hinnebusch B.J., Marceau M., Medigue C., Simonet M., Chenal-Francisque V., Souza B. , Dacheux D., Elliott J.M., Derbise A., Hauser L.J., Garcia E. Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IP32953.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX936398 Genomic DNA. Translation: CAH21491.1.
RefSeq	YP_070768.1. NC_006155.1.
3D structure databases
ProteinModelPortal	Q66A79.
ModBase	Search...
Protein-protein interaction databases
STRING	273123.YPTB2253.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAH21491; CAH21491; YPTB2253.
GeneID	2956140.
KEGG	yps:YPTB2253.
PATRIC	18643398. VBIYerPse22266_2759.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000266425.
KO	K03737.
OMA	ELVERNW.
ProtClustDB	CLSK869636.
Family and domain databases
Gene3D	3.40.50.920. 1 hit. 3.40.920.10. 1 hit. 4.10.780.10. 1 hit.
InterPro	IPR001450. 4Fe4S-bd_dom. IPR017896. 4Fe4S_Fe-S-bd. IPR017900. 4Fe4S_Fe_S_CS. IPR019456. Pyrv-flavodox_OxRtase_EKR. IPR019752. Pyrv/ketoisovalerate_OxRed_cat. IPR002880. Pyrv_Fd/Flavodoxin_OxRdtase_N. IPR011895. Pyrv_flavodox_OxRed. IPR002869. Pyrv_flavodox_OxRed_cen. IPR011766. TPP_enzyme-bd_C. IPR009014. Transketo_C/Pyr-ferredox_oxred. IPR015941. Transketolase-like_C. [Graphical view]
Pfam	PF10371. EKR. 1 hit. PF12838. Fer4_7. 1 hit. PF01558. POR. 1 hit. PF01855. POR_N. 1 hit. PF02775. TPP_enzyme_C. 1 hit. [Graphical view]
PIRSF	PIRSF000159. NifJ. 1 hit.
SMART	SM00890. EKR. 1 hit. [Graphical view]
SUPFAM	SSF53323. Pyrv_Fd/Flavodoxin_OxRdtase. 1 hit. SSF52922. Transketo_C_like. 1 hit.
TIGRFAMs	TIGR02176. pyruv_ox_red. 1 hit.
PROSITE	PS00198. 4FE4S_FER_1. 2 hits. PS51379. 4FE4S_FER_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q66A79_YERPS

Accession

Primary (citable) accession number: Q66A79

Entry history

Integrated into UniProtKB/TrEMBL:	October 11, 2004
Last sequence update:	October 11, 2004
Last modified:	May 1, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)