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Protein

Ribosomal RNA large subunit methyltransferase F

Gene

rlmF

Organism
Yersinia pseudotuberculosis serotype I (strain IP32953)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the adenine in position 1618 of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciYPSE273123:GI1M-2640-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase FUniRule annotation (EC:2.1.1.181UniRule annotation)
Alternative name(s):
23S rRNA mA1618 methyltransferaseUniRule annotation
rRNA adenine N-6-methyltransferaseUniRule annotation
Gene namesi
Name:rlmFUniRule annotation
Ordered Locus Names:YPTB2553
OrganismiYersinia pseudotuberculosis serotype I (strain IP32953)
Taxonomic identifieri273123 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
Proteomesi
  • UP000001011 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 336336Ribosomal RNA large subunit methyltransferase FPRO_0000349986Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ669D4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. METTL16/RlmF family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000218605.
KOiK06970.
OMAiVTLCNPP.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01848. 23SrRNA_methyltr_F. 1 hit.
InterProiIPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR13393. PTHR13393. 1 hit.
PfamiPF05971. Methyltransf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF029038. Mtase_YbiN_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

Q669D4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSYAPENAY QRASTMENKK VFPKEKSGLH PRNRHRSRYD FDALSVSCPE
60 70 80 90 100
LIPFLAPTAY GDISVDFADP LAVKMLNKAL LKHFYGIEYW DIPADSLCPP
110 120 130 140 150
IPGRADYVHH LADLLASCNG EVIPKGKNIA LLDIGVGANC IYPIIGQREY
160 170 180 190 200
GWRFTGTDID SHALSAAKMV VSMNPTLKNT LRLKQQKDPH AIFEGVWAVN
210 220 230 240 250
ERYDATLCNP PFHGSAEEAA ATTRRKLHKL GKNEVAAKPV QNFGGKNSEL
260 270 280 290 300
WCEGGEEGFV SRMVAESVAK AQNCFWFTSL ISKKTTLPAI YHALRYVKAV
310 320 330
EVRTIEMAQG QKVSRFVAWT FLTPEQQAAW VAERWA
Length:336
Mass (Da):37,530
Last modified:October 11, 2004 - v1
Checksum:iAD894E501481FF7A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX936398 Genomic DNA. Translation: CAH21791.1.
RefSeqiWP_002230969.1. NZ_CP009712.1.

Genome annotation databases

EnsemblBacteriaiCAH21791; CAH21791; YPTB2553.
KEGGiyps:YPTB2553.
PATRICi18644099. VBIYerPse22266_3107.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX936398 Genomic DNA. Translation: CAH21791.1.
RefSeqiWP_002230969.1. NZ_CP009712.1.

3D structure databases

ProteinModelPortaliQ669D4.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAH21791; CAH21791; YPTB2553.
KEGGiyps:YPTB2553.
PATRICi18644099. VBIYerPse22266_3107.

Phylogenomic databases

HOGENOMiHOG000218605.
KOiK06970.
OMAiVTLCNPP.

Enzyme and pathway databases

BioCyciYPSE273123:GI1M-2640-MONOMER.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01848. 23SrRNA_methyltr_F. 1 hit.
InterProiIPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR13393. PTHR13393. 1 hit.
PfamiPF05971. Methyltransf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF029038. Mtase_YbiN_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRLMF_YERPS
AccessioniPrimary (citable) accession number: Q669D4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: October 11, 2004
Last modified: September 7, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.