ID   VP2_FCVUR               Reviewed;         106 AA.
AC   Q66916;
DT   09-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   08-NOV-2023, entry version 65.
DE   RecName: Full=Protein VP2;
DE   AltName: Full=Minor capsid protein;
GN   ORFNames=ORF3;
OS   Feline calicivirus (strain Cat/United States/Urbana/1960) (FCV).
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC   Picornavirales; Caliciviridae; Vesivirus; Feline calicivirus.
OX   NCBI_TaxID=292349;
OH   NCBI_TaxID=9685; Felis catus (Cat) (Felis silvestris catus).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=7618275; DOI=10.1006/viro.1995.1354;
RA   Sosnovtsev S.V., Green K.Y.;
RT   "RNA transcripts derived from a cloned full-length copy of the feline
RT   calicivirus genome do not require VpG for infectivity.";
RL   Virology 210:383-390(1995).
RN   [2]
RP   PROTEIN SEQUENCE OF 1-20 AND 102-106, AND IDENTIFICATION.
RX   PubMed=11062050; DOI=10.1006/viro.2000.0579;
RA   Sosnovtsev S.V., Green K.Y.;
RT   "Identification and genomic mapping of the ORF3 and VPg proteins in feline
RT   calicivirus virions.";
RL   Virology 277:193-203(2000).
RN   [3]
RP   FUNCTION.
RX   PubMed=15767403; DOI=10.1128/jvi.79.7.4012-4024.2005;
RA   Sosnovtsev S.V., Belliot G., Chang K.O., Onwudiwe O., Green K.Y.;
RT   "Feline calicivirus VP2 is essential for the production of infectious
RT   virions.";
RL   J. Virol. 79:4012-4024(2005).
RN   [4]
RP   INTERACTION WITH CAPSID PROTEIN.
RX   PubMed=16432023; DOI=10.1099/vir.0.81456-0;
RA   Kaiser W.J., Chaudhry Y., Sosnovtsev S.V., Goodfellow I.G.;
RT   "Analysis of protein-protein interactions in the feline calicivirus
RT   replication complex.";
RL   J. Gen. Virol. 87:363-368(2006).
CC   -!- FUNCTION: Minor structural protein present in one or two copies per
CC       virion. Does not seem to play a role in capsid assembly, but is
CC       essential for production of infectious virus.
CC       {ECO:0000269|PubMed:15767403}.
CC   -!- SUBUNIT: May interact with capsid protein.
CC   -!- SUBCELLULAR LOCATION: Virion. Host cytoplasm.
CC   -!- MISCELLANEOUS: Translated by a ribosomal termination-reinitiation
CC       process from the bicistronic mRNA coding for VP1 and VP2.
CC   -!- SIMILARITY: Belongs to the vesivirus VP2 protein family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L40021; AAA79325.1; -; Genomic_RNA.
DR   RefSeq; NP_783198.1; NC_001481.2.
DR   SMR; Q66916; -.
DR   GeneID; 1502253; -.
DR   KEGG; vg:1502253; -.
DR   Proteomes; UP000001098; Segment.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0044423; C:virion component; IEA:UniProtKB-KW.
DR   InterPro; IPR007996; Vesivirus_VP2.
DR   Pfam; PF05332; Vesi_VP2; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Host cytoplasm; Reference proteome; Virion.
FT   CHAIN           1..106
FT                   /note="Protein VP2"
FT                   /id="PRO_0000100125"
SQ   SEQUENCE   106 AA;  12199 MW;  DCD55D2DE1967F13 CRC64;
     MNSILGLIDT VTNTIGKAQQ IELDKAALGQ QRELALQRMN LDRQALNNQV EQFNKILEQR
     VQGPLQSVRL ARAAGFRVDP YSYTNQNFYD DQLNAIRLSY RNLFKN
//