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Q66916 (VP2_FCVUR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein VP2
Alternative name(s):
Minor capsid protein
Gene names
ORF Names:ORF3
OrganismFeline calicivirus (strain Cat/United States/Urbana/1960) (FCV) [Reference proteome]
Taxonomic identifier292349 [NCBI]
Taxonomic lineageVirusesssRNA positive-strand viruses, no DNA stageCaliciviridaeVesivirus
Virus hostFelis catus (Cat) (Felis silvestris catus) [TaxID: 9685]

Protein attributes

Sequence length106 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Minor structural protein present in one or two copies per virion. Does not seem to play a role in capsid assembly, but is essential for production of infectious virus. Ref.3

Subunit structure

May interact with capsid protein.

Subcellular location

Virion. Host cytoplasm.

Miscellaneous

Translated by a ribosomal terminaition-reinitiation process from the bicistronic mRNA coding for VP1 and VP2.

Sequence similarities

Belongs to the vesivirus VP2 protein family.

Ontologies

Keywords
   Cellular componentHost cytoplasm
Virion
   Technical termComplete proteome
Direct protein sequencing
Reference proteome
Gene Ontology (GO)
   Cellular_componenthost cell cytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

virion

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 106106Protein VP2
PRO_0000100125

Sequences

Sequence LengthMass (Da)Tools
Q66916 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: DCD55D2DE1967F13

FASTA10612,199
        10         20         30         40         50         60 
MNSILGLIDT VTNTIGKAQQ IELDKAALGQ QRELALQRMN LDRQALNNQV EQFNKILEQR 

        70         80         90        100 
VQGPLQSVRL ARAAGFRVDP YSYTNQNFYD DQLNAIRLSY RNLFKN 

« Hide

References

[1]"RNA transcripts derived from a cloned full-length copy of the feline calicivirus genome do not require VpG for infectivity."
Sosnovtsev S.V., Green K.Y.
Virology 210:383-390(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]"Identification and genomic mapping of the ORF3 and VPg proteins in feline calicivirus virions."
Sosnovtsev S.V., Green K.Y.
Virology 277:193-203(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 1-20 AND 102-106, IDENTIFICATION.
[3]"Feline calicivirus VP2 is essential for the production of infectious virions."
Sosnovtsev S.V., Belliot G., Chang K.O., Onwudiwe O., Green K.Y.
J. Virol. 79:4012-4024(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[4]"Analysis of protein-protein interactions in the feline calicivirus replication complex."
Kaiser W.J., Chaudhry Y., Sosnovtsev S.V., Goodfellow I.G.
J. Gen. Virol. 87:363-368(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH CAPSID PROTEIN.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L40021 Genomic RNA. Translation: AAA79325.1.
RefSeqNP_783198.1. NC_001481.2.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1502253.

Family and domain databases

InterProIPR007996. Vesivirus_VP2.
[Graphical view]
PfamPF05332. DUF743. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameVP2_FCVUR
AccessionPrimary (citable) accession number: Q66916
Entry history
Integrated into UniProtKB/Swiss-Prot: November 9, 2004
Last sequence update: November 1, 1996
Last modified: May 29, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families