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Protein

Protein VP2

Gene

ORF3

Organism
Feline calicivirus (strain Cat/United States/Urbana/1960) (FCV)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Minor structural protein present in one or two copies per virion. Does not seem to play a role in capsid assembly, but is essential for production of infectious virus.1 Publication

Names & Taxonomyi

Protein namesi
Recommended name:
Protein VP2
Alternative name(s):
Minor capsid protein
Gene namesi
ORF Names:ORF3
OrganismiFeline calicivirus (strain Cat/United States/Urbana/1960) (FCV)
Taxonomic identifieri292349 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stageCaliciviridaeVesivirus
Virus hostiFelis catus (Cat) (Felis silvestris catus) [TaxID: 9685]
Proteomesi
  • UP000001098 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Host cytoplasm, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 106106Protein VP2PRO_0000100125Add
BLAST

Interactioni

Subunit structurei

May interact with capsid protein.

Family & Domainsi

Sequence similaritiesi

Belongs to the vesivirus VP2 protein family.Curated

Family and domain databases

InterProiIPR007996. Vesivirus_VP2.
[Graphical view]
PfamiPF05332. DUF743. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q66916-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSILGLIDT VTNTIGKAQQ IELDKAALGQ QRELALQRMN LDRQALNNQV
60 70 80 90 100
EQFNKILEQR VQGPLQSVRL ARAAGFRVDP YSYTNQNFYD DQLNAIRLSY

RNLFKN
Length:106
Mass (Da):12,199
Last modified:November 1, 1996 - v1
Checksum:iDCD55D2DE1967F13
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L40021 Genomic RNA. Translation: AAA79325.1.
RefSeqiNP_783198.1. NC_001481.2.

Genome annotation databases

GeneIDi1502253.
KEGGivg:1502253.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L40021 Genomic RNA. Translation: AAA79325.1.
RefSeqiNP_783198.1. NC_001481.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1502253.
KEGGivg:1502253.

Family and domain databases

InterProiIPR007996. Vesivirus_VP2.
[Graphical view]
PfamiPF05332. DUF743. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "RNA transcripts derived from a cloned full-length copy of the feline calicivirus genome do not require VpG for infectivity."
    Sosnovtsev S.V., Green K.Y.
    Virology 210:383-390(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
  2. "Identification and genomic mapping of the ORF3 and VPg proteins in feline calicivirus virions."
    Sosnovtsev S.V., Green K.Y.
    Virology 277:193-203(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 1-20 AND 102-106, IDENTIFICATION.
  3. "Feline calicivirus VP2 is essential for the production of infectious virions."
    Sosnovtsev S.V., Belliot G., Chang K.O., Onwudiwe O., Green K.Y.
    J. Virol. 79:4012-4024(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  4. "Analysis of protein-protein interactions in the feline calicivirus replication complex."
    Kaiser W.J., Chaudhry Y., Sosnovtsev S.V., Goodfellow I.G.
    J. Gen. Virol. 87:363-368(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH CAPSID PROTEIN.

Entry informationi

Entry nameiVP2_FCVUR
AccessioniPrimary (citable) accession number: Q66916
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 9, 2004
Last sequence update: November 1, 1996
Last modified: June 24, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Miscellaneous

Translated by a ribosomal terminaition-reinitiation process from the bicistronic mRNA coding for VP1 and VP2.

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.