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Q66916

- VP2_FCVUR

UniProt

Q66916 - VP2_FCVUR

Protein

Protein VP2

Gene

ORF3

Organism
Feline calicivirus (strain Cat/United States/Urbana/1960) (FCV)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Minor structural protein present in one or two copies per virion. Does not seem to play a role in capsid assembly, but is essential for production of infectious virus.1 Publication

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein VP2
    Alternative name(s):
    Minor capsid protein
    Gene namesi
    ORF Names:ORF3
    OrganismiFeline calicivirus (strain Cat/United States/Urbana/1960) (FCV)
    Taxonomic identifieri292349 [NCBI]
    Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageCaliciviridaeVesivirus
    Virus hostiFelis catus (Cat) (Felis silvestris catus) [TaxID: 9685]
    ProteomesiUP000001098: Genome

    Subcellular locationi

    GO - Cellular componenti

    1. host cell cytoplasm Source: UniProtKB-SubCell
    2. virion Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Host cytoplasm, Virion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 106106Protein VP2PRO_0000100125Add
    BLAST

    Interactioni

    Subunit structurei

    May interact with capsid protein.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the vesivirus VP2 protein family.Curated

    Family and domain databases

    InterProiIPR007996. Vesivirus_VP2.
    [Graphical view]
    PfamiPF05332. DUF743. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q66916-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNSILGLIDT VTNTIGKAQQ IELDKAALGQ QRELALQRMN LDRQALNNQV    50
    EQFNKILEQR VQGPLQSVRL ARAAGFRVDP YSYTNQNFYD DQLNAIRLSY 100
    RNLFKN 106
    Length:106
    Mass (Da):12,199
    Last modified:November 1, 1996 - v1
    Checksum:iDCD55D2DE1967F13
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L40021 Genomic RNA. Translation: AAA79325.1.
    RefSeqiNP_783198.1. NC_001481.2.

    Genome annotation databases

    GeneIDi1502253.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L40021 Genomic RNA. Translation: AAA79325.1 .
    RefSeqi NP_783198.1. NC_001481.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 1502253.

    Family and domain databases

    InterProi IPR007996. Vesivirus_VP2.
    [Graphical view ]
    Pfami PF05332. DUF743. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "RNA transcripts derived from a cloned full-length copy of the feline calicivirus genome do not require VpG for infectivity."
      Sosnovtsev S.V., Green K.Y.
      Virology 210:383-390(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
    2. "Identification and genomic mapping of the ORF3 and VPg proteins in feline calicivirus virions."
      Sosnovtsev S.V., Green K.Y.
      Virology 277:193-203(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 1-20 AND 102-106, IDENTIFICATION.
    3. "Feline calicivirus VP2 is essential for the production of infectious virions."
      Sosnovtsev S.V., Belliot G., Chang K.O., Onwudiwe O., Green K.Y.
      J. Virol. 79:4012-4024(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    4. "Analysis of protein-protein interactions in the feline calicivirus replication complex."
      Kaiser W.J., Chaudhry Y., Sosnovtsev S.V., Goodfellow I.G.
      J. Gen. Virol. 87:363-368(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH CAPSID PROTEIN.

    Entry informationi

    Entry nameiVP2_FCVUR
    AccessioniPrimary (citable) accession number: Q66916
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 9, 2004
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Translated by a ribosomal terminaition-reinitiation process from the bicistronic mRNA coding for VP1 and VP2.

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3