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Protein

G-protein coupled receptor 74

Gene

74

Organism
Equine herpesvirus 2 (strain 86/87) (EHV-2)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
G-protein coupled receptor 74
Gene namesi
Name:74
OrganismiEquine herpesvirus 2 (strain 86/87) (EHV-2)
Taxonomic identifieri82831 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeGammaherpesvirinaePercavirus
Virus hostiEquus caballus (Horse) [TaxID: 9796]
Proteomesi
  • UP000007083 Componenti: Genome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei50 – 70HelicalSequence analysisAdd BLAST21
Transmembranei85 – 105HelicalSequence analysisAdd BLAST21
Transmembranei121 – 141HelicalSequence analysisAdd BLAST21
Transmembranei160 – 180HelicalSequence analysisAdd BLAST21
Transmembranei210 – 230HelicalSequence analysisAdd BLAST21
Transmembranei252 – 272HelicalSequence analysisAdd BLAST21
Transmembranei295 – 315HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Host membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004059811 – 330G-protein coupled receptor 74Add BLAST330

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi117 ↔ 195PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliQ66673.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

OrthoDBiVOG090000NY.

Family and domain databases

InterProiView protein in InterPro
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiView protein in PROSITE
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q66673-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESGSGSGAA LNSTPFPTYS TPNFTDDYDW NSSDWYGLTN QCQAVSFSKL
60 70 80 90 100
IVVPCLVILL VFCLIGNLWL LFKLLEKTVK KVSTFILILM CLNSFWGCLC
110 120 130 140 150
MIFSIVENFA EFSTSVCKLR MVVFWVYVFF DMFLICWLCF DTWCAVWFSV
160 170 180 190 200
RRTEANQKCW VFCTVALIIL AFILSMQKAL HVEAIKEYGQ VRSSCQFHKE
210 220 230 240 250
THSTLKVFNV AVSVNVLGFL LPLLFLCIFY GMCLWKLYKA VFKTKTKVIK
260 270 280 290 300
TMLLFVFMFL LTWGPYYILS FIDGLLSAGY ISESCSLKKT LGLMLPLLGL
310 320 330
WGMAHGGLQV FIYILCNSHF NKSLFSCFKK
Length:330
Mass (Da):37,794
Last modified:November 1, 1996 - v1
Checksum:iE1B8A057A368A19D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U20824 Genomic DNA. Translation: AAC13861.1.
PIRiS55595.
RefSeqiNP_042670.1. NC_001650.2.

Genome annotation databases

GeneIDi1461030.
KEGGivg:1461030.

Similar proteinsi

Entry informationi

Entry nameiVG74_EHV2
AccessioniPrimary (citable) accession number: Q66673
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: November 1, 1996
Last modified: September 27, 2017
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families