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Protein

Triplex capsid protein 1

Gene

TRX1

Organism
Equine herpesvirus 2 (strain 86/87) (EHV-2)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Triplex capsid protein 1
Gene namesi
Name:TRX1
Ordered Locus Names:62
OrganismiEquine herpesvirus 2 (strain 86/87) (EHV-2)
Taxonomic identifieri82831 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeGammaherpesvirinaePercavirus
Virus hostiEquus caballus (Horse) [TaxID: 9796]
Proteomesi
  • UP000007083 Componenti: Genome

Subcellular locationi

  • Virion
  • Host nucleus

GO - Cellular componenti

Keywords - Cellular componenti

Capsid protein, Host nucleus, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004060421 – 338Triplex capsid protein 1Add BLAST338

Interactioni

Subunit structurei

Interacts with TRX2, MCP and capsid vertex component 2/CVC2.

Family & Domainsi

Sequence similaritiesi

Belongs to the herpesviridae TRX1 protein family.

Phylogenomic databases

OrthoDBiVOG090000FJ.

Family and domain databases

HAMAPiMF_04018. HSV_TRX1. 1 hit.
InterProiView protein in InterPro
IPR004999. Herpes_1.
PfamiView protein in Pfam
PF03327. Herpes_VP19C. 1 hit.

Sequencei

Sequence statusi: Complete.

Q66664-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTKEVTPRG DSGEKLARDL LRLVPPQTHK LGTFRASELG RDLRAIVANY
60 70 80 90 100
APKTISGHIQ IFRDDFIAPP YRQPLYGEFL VHAKTFHPQE PRGTFVFAFS
110 120 130 140 150
VGDGPECTSV DTIFSPVSLF RVCGLGADAA PHTHRISHIW YESESDFLNV
160 170 180 190 200
AANVRELIEN CSLHKFLSPV GPLVQNIQST FLNKITTVVK GEVLSNRSPP
210 220 230 240 250
ENIKLVLPSD LFFDMDETCP YPPSGDPVKP RVCYYVCILY VMVNNIPSAS
260 270 280 290 300
LQFFRTGKGA SDVVFFLRRY YSDAIANKIT VLGDNLDINN LTLGAVCMLG
310 320 330
YSSSQSTPGR GNLHFRSYSL PTVEVSDFVA QPGSWTLI
Length:338
Mass (Da):37,509
Last modified:November 1, 1996 - v1
Checksum:iC6E87A8C369B742F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U20824 Genomic DNA. Translation: AAC13850.1.
PIRiS55657.
RefSeqiNP_042659.1. NC_001650.2.

Genome annotation databases

GeneIDi1461038.
KEGGivg:1461038.

Similar proteinsi

Entry informationi

Entry nameiTRX1_EHV2
AccessioniPrimary (citable) accession number: Q66664
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: November 1, 1996
Last modified: February 15, 2017
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families