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Protein

Triplex capsid protein 2

Gene

TRX2

Organism
Equine herpesvirus 2 (strain 86/87) (EHV-2)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.UniRule annotation

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Triplex capsid protein 2UniRule annotation
Gene namesi
Name:TRX2UniRule annotation
Ordered Locus Names:26
OrganismiEquine herpesvirus 2 (strain 86/87) (EHV-2)
Taxonomic identifieri82831 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeGammaherpesvirinaePercavirus
Virus hostiEquus caballus (Horse) [TaxID: 9796]
Proteomesi
  • UP000007083 Componenti: Genome

Subcellular locationi

  • Virion UniRule annotation
  • Host nucleus UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Capsid protein, Host nucleus, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004060741 – 300Triplex capsid protein 2Add BLAST300

Interactioni

Subunit structurei

Interacts with TRX1 and major capisd protein/MCP.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the herpesviridae TRX2 protein family.UniRule annotation

Phylogenomic databases

OrthoDBiVOG090000IF.

Family and domain databases

HAMAPiMF_04019. HSV_TRX2. 1 hit.
InterProiView protein in InterPro
IPR002690. Herpes_capsid_2.
PfamiView protein in Pfam
PF01802. Herpes_V23. 1 hit.

Sequencei

Sequence statusi: Complete.

Q66629-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQVDSRIVVT LTSRLYADEI SKLQERVGSV VPLKDSHRLQ NLNSVGMYSV
60 70 80 90 100
YMRNVAPDFV AMFSYLSEAT LAILDEVTPD TLVFSRLDHS QNYELKNVYY
110 120 130 140 150
PSFAWHSHTL LTVVPPVFGR EAATVALESN GFEIVFPVVM PHALAQAVLQ
160 170 180 190 200
KLMLYNIYAR LSDANVGDVN MDHVRFHATT LHHMGRAYTL HIDQANPGGM
210 220 230 240 250
LGLLDNLAIY LAIISALLPN SLARLLPAIM RHEQHELLNI FAGVAPPDDG
260 270 280 290 300
GDFNIEDDMQ KMESFMAYMQ SVSSIFNLGP KLRLGQYSSE TQSGTAWLAS
Length:300
Mass (Da):33,418
Last modified:November 1, 1996 - v1
Checksum:i0056525A5A7B4DCB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U20824 Genomic DNA. Translation: AAC13813.1.
PIRiS55620.
RefSeqiNP_042622.1. NC_001650.2.

Genome annotation databases

GeneIDi1461081.
KEGGivg:1461081.

Similar proteinsi

Entry informationi

Entry nameiTRX2_EHV2
AccessioniPrimary (citable) accession number: Q66629
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: November 1, 1996
Last modified: February 15, 2017
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families