Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Capsid vertex component 2

Gene

CVC2

Organism
Equine herpesvirus 2 (strain 86/87) (EHV-2)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes. Participates in the interaction between the capsid and the tegument through interaction with the large tegument protein/LTP.UniRule annotation

GO - Biological processi

Keywordsi

Biological processHost-virus interaction, Viral genome packaging, Viral penetration into host nucleus, Viral release from host cell, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Capsid vertex component 2UniRule annotation
Gene namesi
Name:CVC2UniRule annotation
Ordered Locus Names:19
OrganismiEquine herpesvirus 2 (strain 86/87) (EHV-2)
Taxonomic identifieri82831 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeGammaherpesvirinaePercavirus
Virus hostiEquus caballus (Horse) [TaxID: 9796]
Proteomesi
  • UP000007083 Componenti: Genome

Subcellular locationi

  • Virion UniRule annotation
  • Host nucleus UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Capsid protein, Host nucleus, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004061691 – 564Capsid vertex component 2Add BLAST564

Interactioni

Subunit structurei

Heterodimerizes with CVC1. Interacts with major capsid protein/MCP and triplex capsid protein 1/TRX1 at the pentamer vertices. Interacts with the large tegument protein/LTP.UniRule annotation

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 45Interaction with major capsid protein/MCPUniRule annotationAdd BLAST45

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi119 – 130Poly-GlyAdd BLAST12

Sequence similaritiesi

Belongs to the herpesviridae CVC2 protein family.UniRule annotation

Phylogenomic databases

OrthoDBiVOG0900005N.

Family and domain databases

HAMAPiMF_04025. HSV_CVC2. 1 hit.
InterProiView protein in InterPro
IPR002493. Herpes_UL25.
PfamiView protein in Pfam
PF01499. Herpes_UL25. 1 hit.

Sequencei

Sequence statusi: Complete.

Q66622-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQAARKRWPP SVAFWSPSPK HYVRVDRDSL RETRRLASSL RRNALAARVA
60 70 80 90 100
RVKAGMLRAE LGNLSQLQIA HAHGVLADLA RLEQATALHV AGDGRGSGNP
110 120 130 140 150
PTSPGQGHPL SWGNSDSHGG GGGPGGGGGG ELLITISPDG PTFSVKDDFR
160 170 180 190 200
TEFISGLYTR QSQWLPFYGP WYAAMTDSAM QRRVFPKELK GNVNFQNSTS
210 220 230 240 250
LKLMTGLLEV LASATEDFYT DGRNLSDVNA ALCLLNGYYC LRTPAPLPST
260 270 280 290 300
YGELLADLDK KMEFLIADLK RDASNTDFSF AFSNPRQLET VAPLNRQGAY
310 320 330 340 350
APDFFGRHKM FAVMSDAGMF PNTKQTAASA QDPGARDIVY LITNAVFGEN
360 370 380 390 400
VPPFITYQLN LRTGLKALEL LIVVYIVLEN AHVQHNTVNR RLQLPALLGD
410 420 430 440 450
QYKRPAAQRP QPQQPAAMFK KGFLFSFVVK NYMVPVLTRR PQTPASSLFP
460 470 480 490 500
GAVLLALETA DAASAGGGSG QTLGGHLINL SGKKYDQLFD VLNQKLTFRD
510 520 530 540 550
VQGLIGAQTA LRLTLERGLN LLLSKPSPLT SATEVISTQF GGGDDYDSLY
560
FLILGCLPVT MAVV
Length:564
Mass (Da):61,245
Last modified:November 1, 1996 - v1
Checksum:i7E4B52FBC97248B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U20824 Genomic DNA. Translation: AAC13806.1.
PIRiS55613.
RefSeqiNP_042615.1. NC_001650.2.

Genome annotation databases

GeneIDi1461017.
KEGGivg:1461017.

Similar proteinsi

Entry informationi

Entry nameiCVC2_EHV2
AccessioniPrimary (citable) accession number: Q66622
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: November 1, 1996
Last modified: November 22, 2017
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families