Reviewed, UniProtKB/Swiss-Prot Q662R1 (SYN_BORGA)

Names and origin

Protein names

Recommended name:
    Asparaginyl-tRNA synthetase
    EC=6.1.1.22
Alternative name(s):
    Asparagine--tRNA ligase
      Short name=AsnRS

Gene names

Name:	asnS
Ordered Locus Names:	BG0102

Organism

Borrelia garinii [Complete proteome] [HAMAP]

Taxonomic identifier

29519 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length	462 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + L-asparaginyl-tRNA(Asn). HAMAP MF_00534
Subunit structure	Homodimer By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00534
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	asparaginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP aspartyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP asparagine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP aspartate-tRNA ligase activity Inferred from electronic annotation. Source: InterPro nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 462	462	Asparaginyl-tRNA synthetase HAMAP MF_00534		PRO_0000176396

Sequences

	Sequence		Length	Mass (Da)
	Q662R1-1 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 0FF557DF238D7BF3	FASTA	462	53,167
	10 20 30 40 50 60 MFSSIKDILE NPILNSNVTI NGWIRTKRSN GKIGFIEIND GSTLKGIQAV INEEENQFTE 70 80 90 100 110 120 KDLKKLTTGA SISLTGLLVE SPAKGQNYEI KIYSFNVIGE ADSKTYPLQK KRHTFEFLRE 130 140 150 160 170 180 IPHLRIRTNT FGAIARVRNK ISYKIHEYFQ KNGFFYINTP IITSNDGEGA GEMFRVSTLK 190 200 210 220 230 240 FNKPNNSLSN IDFKDDFFGK EAFLSVTGQL HGEAYAMALS KIYTFGPTFR AENSNTTRHA 250 260 270 280 290 300 SEFWMIEPEM AFYKLNDNIS LAEDLLKYLL SSILNECSQD MDFLENYIEK GLIKKLENVI 310 320 330 340 350 360 NSNFEVITYT KAIEILESSK KNFEIKPCWG IDLQTDHERY LTEEIFKKPI AVIDYPKNFK 370 380 390 400 410 420 AFYMKINKDN KTVKGMDILV PRIGEIIGGS EREDDLQKLE NRIKELNLNI EHLNWYLDLR 430 440 450 460 RFGSTPHSGF GLGLERLVQY TTGISNIRDS IPFPRTPKNL YF

References

[1]

"Comparative analysis of the Borrelia garinii genome." Gloeckner G., Lehmann R., Romualdi A., Pradella S., Schulte-Spechtel U., Schilhabel M., Wilske B., Suehnel J., Platzer M. Nucleic Acids Res. 32:6038-6046(2004) [PubMed: 15547252] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PBi.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000013 Genomic DNA. Translation: AAU06960.1.
RefSeq	YP_072552.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2957176.
GenomeReviews	Gene locus BG0102 in contig CP000013_GR.
KEGG	bga:BG0102.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q662R1.
OMA	LQKKRHS.
Enzyme and pathway databases
BioCyc	BGAR290434:BG0102-MON.
BRENDA	6.1.1.22. 294970.
Family and domain databases
HAMAP	MF_00534. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II_cons-reg. IPR004522. Asn-tRNA-synth_IIb. IPR002312. Asp-tRNA-synth_IIb. IPR012340. NA-bd_OB-fold. IPR004365. NA_bd_OB_tRNA-helicase. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit.
Pfam	PF00152. tRNA-synt_2. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
PRINTS	PR01042. TRNASYNTHASP.
TIGRFAMs	TIGR00457. asnS. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYN_BORGA

Accession

Primary (citable) accession number: Q662R1

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 15, 2005
Last sequence update:	October 11, 2004
Last modified:	November 3, 2009
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)