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Q660S8 (SYR_BORGA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:BG0607
OrganismBorrelia garinii (strain PBi) [Complete proteome] [HAMAP]
Taxonomic identifier290434 [NCBI]
Taxonomic lineageBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeBorreliaBorrelia burgdorferi group

Protein attributes

Sequence length585 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 585585Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000241993

Regions

Motif127 – 13711"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q660S8 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 17357A248B6E3F6E

FASTA58566,837
        10         20         30         40         50         60 
MTKSVKKNIK NEISIIVANL ALSKNIKLDK ININIQKPPK SDLGDISILI FELSKTLELP 

        70         80         90        100        110        120 
IATISEEIIK TLKSKYEIKA MGPYLNIKIP RKEYINNTIQ MVNAQKDSYG TSKYLDNKKI 

       130        140        150        160        170        180 
ILEFSSPNTN KPLHVGHLRN DAIGESLSRI LKAVGAKITK INLINDRGVH ICKSMLAYKK 

       190        200        210        220        230        240 
FGNCITPEKA FKKGDHLIGE FYVEYNKYSQ ENENAEKEIQ DLLLKWEQKD KNTIELWEKL 

       250        260        270        280        290        300 
NKWAIEGIKE TYKTTNISFD KIYLESEIFE IGKNVVLEGL EKGFCYKRED GAICIDLPSD 

       310        320        330        340        350        360 
SDEKAEAKAK QKVLIRSNGT SIYLTQDLGN IAIRTKEFNF DEMIYVVGSE QIQHFKNLFF 

       370        380        390        400        410        420 
VSEKLGISKN KQLIHLSHGM VNLIDGKMKS REGNVIDGDN LILELIESIM PEITQKIDNK 

       430        440        450        460        470        480 
ENAKKNALNI ALGAIHYYLL KSAVHKDIVF NKKESLSFTG NSGPYIQYVG ARINSILEKY 

       490        500        510        520        530        540 
NALSIPIIKK INFELLKHEK EWEIIKIISE LEENIIKAAK DLNPSILTNY SYSLAKHFSA 

       550        560        570        580 
YYQEVKVIDI NNTDLTAARI EFLKTILQTI KNCMHLLNIP YMLKM 

« Hide

References

[1]"Comparative analysis of the Borrelia garinii genome."
Gloeckner G., Lehmann R., Romualdi A., Pradella S., Schulte-Spechtel U., Schilhabel M., Wilske B., Suehnel J., Platzer M.
Nucleic Acids Res. 32:6038-6046(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PBi.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000013 Genomic DNA. Translation: AAU07443.1.
RefSeqYP_073035.1. NC_006156.1.

3D structure databases

ProteinModelPortalQ660S8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING290434.BG0607.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAU07443; AAU07443; BG0607.
GeneID2957800.
KEGGbga:BG0607.
PATRIC20566783. VBIBorGar102262_0702.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000247211.
KOK01887.
OMADGTAVYM.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycBGAR290434:BG0607-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_BORGA
AccessionPrimary (citable) accession number: Q660S8
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: October 11, 2004
Last modified: April 16, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries