Q660Q0 (ACKA_BORGA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetate kinase
EC=2.7.2.1

Alternative name(s):
Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	BG0641

Organism

Borrelia garinii [Complete proteome] [HAMAP]

Taxonomic identifier

29519 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length	405 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 405	405	Acetate kinase HAMAP MF_00020		PRO_0000107537

Sequences

	Sequence		Length	Mass (Da)
	Q660Q0-1 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: CE70B4048DB2770E	FASTA	405	45,619
	10 20 30 40 50 60 MKILIINTGS SSLKFAIYQY ENSKKLISGV IEKIKEQKSI IKIINTDGSI TERFEKGIEN 70 80 90 100 110 120 HPKAIEKMFK ILLNSNSKIL KNISEIKIIG HRVVHGGSYF KNSVILKNSN LDKLKQSSKL 130 140 150 160 170 180 APLHNPSAIA AIETVLKILP HAKQVLCFDT SWHQTIKKHA FLYATPYSWY KEHNIRKYGF 190 200 210 220 230 240 HGLSYSYVTK RSSEILNKKI DNLNLIILHL GNGASINAVK DGKSYDTSMG ITPLEGLVMG 250 260 270 280 290 300 TRSGDIDPSI INLMSTILNK NTKQIEEILN KESGILGISE KSNDMRDIWN KIEEGEYQSK 310 320 330 340 350 360 LAVEIMTYRV KKYIGSYIAI LDFNVDAIVF TGGIGVVDYE VRELALKGFE KIGIELDLEK 370 380 390 400 NKMAQNKNLE SEISTIKSKV KILAIPTNEE STILEDIYNL IPKNL

References

[1]

"Comparative analysis of the Borrelia garinii genome." Gloeckner G., Lehmann R., Romualdi A., Pradella S., Schulte-Spechtel U., Schilhabel M., Wilske B., Suehnel J., Platzer M. Nucleic Acids Res. 32:6038-6046(2004) [PubMed: 15547252] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PBi.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000013 Genomic DNA. Translation: AAU07471.1.
RefSeq	YP_073063.1.
3D structure databases
ProteinModelPortal	Q660Q0.
SMR	Q660Q0. Positions 1-403.
ModBase	Search...
Genome annotation databases
EnsemblBacteria	EBBORT00000007741; EBBORP00000007116; EBBORG00000007740.
GeneID	2957780.
GenomeReviews	Gene locus BG0641 in contig CP000013_GR.
KEGG	bga:BG0641.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG285863.
OMA	LNRHSGL.
PhylomeDB	Q660Q0.
ProtClustDB	PRK00180.
Enzyme and pathway databases
BioCyc	BGAR290434:BG0641-MONOMER.
BRENDA	2.7.2.1. 294970.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. Acetate_kinase. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_BORGA

Accession

Primary (citable) accession number: Q660Q0

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 2005
Last sequence update:	October 11, 2004
Last modified:	August 10, 2010
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)