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Q660Q0 (ACKA_BORGA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:BG0641
OrganismBorrelia garinii [Complete proteome] [HAMAP]
Taxonomic identifier29519 [NCBI]
Taxonomic lineageBacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length405 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 405405Acetate kinase HAMAP MF_00020
PRO_0000107537

Sequences

Sequence LengthMass (Da)Tools
Q660Q0 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: CE70B4048DB2770E

FASTA40545,619
        10         20         30         40         50         60 
MKILIINTGS SSLKFAIYQY ENSKKLISGV IEKIKEQKSI IKIINTDGSI TERFEKGIEN 

        70         80         90        100        110        120 
HPKAIEKMFK ILLNSNSKIL KNISEIKIIG HRVVHGGSYF KNSVILKNSN LDKLKQSSKL 

       130        140        150        160        170        180 
APLHNPSAIA AIETVLKILP HAKQVLCFDT SWHQTIKKHA FLYATPYSWY KEHNIRKYGF 

       190        200        210        220        230        240 
HGLSYSYVTK RSSEILNKKI DNLNLIILHL GNGASINAVK DGKSYDTSMG ITPLEGLVMG 

       250        260        270        280        290        300 
TRSGDIDPSI INLMSTILNK NTKQIEEILN KESGILGISE KSNDMRDIWN KIEEGEYQSK 

       310        320        330        340        350        360 
LAVEIMTYRV KKYIGSYIAI LDFNVDAIVF TGGIGVVDYE VRELALKGFE KIGIELDLEK 

       370        380        390        400 
NKMAQNKNLE SEISTIKSKV KILAIPTNEE STILEDIYNL IPKNL

« Hide

References

[1]"Comparative analysis of the Borrelia garinii genome."
Gloeckner G., Lehmann R., Romualdi A., Pradella S., Schulte-Spechtel U., Schilhabel M., Wilske B., Suehnel J., Platzer M.
Nucleic Acids Res. 32:6038-6046(2004) [PubMed: 15547252] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PBi.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000013 Genomic DNA. Translation: AAU07471.1.
RefSeqYP_073063.1. NC_006156.1.

3D structure databases

ProteinModelPortalQ660Q0.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBORT00000007741; EBBORP00000007116; EBBORG00000007740.
GeneID2957780.
GenomeReviewsGene locus BG0641 in contig CP000013_GR.
KEGGbga:BG0641.
PATRIC20566849. VBIBorGar102262_0729.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000007562.
HOGENOMHBG285863.
OMAARNENSE.
PhylomeDBQ660Q0.
ProtClustDBPRK00180.

Enzyme and pathway databases

BioCycBGAR290434:BG0641-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_BORGA
AccessionPrimary (citable) accession number: Q660Q0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: October 11, 2004
Last modified: January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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