Q65ZV5 (KCY2_BORGA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase 2
Short name=CK 2
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase 2
Short name=CMP kinase 2

Gene names

Name:	cmk2
Ordered Locus Names:	BG0844

Organism

Borrelia garinii [Complete proteome] [HAMAP]

Taxonomic identifier

29519 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length	178 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00239
Subcellular location	Cytoplasm By similarity HAMAP MF_00239.
Sequence similarities	Belongs to the cytidylate kinase family. Type 2 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 178	178	Cytidylate kinase 2 HAMAP MF_00239		PRO_0000132029
Regions
	Nucleotide binding	7 – 15	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q65ZV5 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 467DDD9D6A1273E7	FASTA	178	20,850
	10 20 30 40 50 60 MKIALSGKSG CGNTTVSSMI AKHYGLEFIN YTFHDIARER NIPFSEFYEK EIIGRDDYYW 70 80 90 100 110 120 DMYLDKRLSL LSKKNNTVLA SRLAIWISKS ADLKIYLYAK MEVRAERIMT REGGMYSDVL 130 140 150 160 170 SSTFNRDEND KKRYLSIYNI DIDDYSSKTD LVIDVTNINS NEVFELIRDE IDKRNLKN

References

[1]

"Comparative analysis of the Borrelia garinii genome." Gloeckner G., Lehmann R., Romualdi A., Pradella S., Schulte-Spechtel U., Schilhabel M., Wilske B., Suehnel J., Platzer M. Nucleic Acids Res. 32:6038-6046(2004) [PubMed: 15547252] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PBi.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000013 Genomic DNA. Translation: AAU07666.1.
RefSeq	YP_073258.1. NC_006156.1.
3D structure databases
ProteinModelPortal	Q65ZV5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBORT00000007768; EBBORP00000007143; EBBORG00000007767.
GeneID	2957682.
GenomeReviews	Gene locus BG0844 in contig CP000013_GR.
KEGG	bga:BG0844.
PATRIC	20567263. VBIBorGar102262_0928.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000007179.
HOGENOM	HBG578180.
OMA	CAGFIFR.
ProtClustDB	PRK04182.
Enzyme and pathway databases
BioCyc	BGAR290434:BG0844-MONOMER.
Family and domain databases
HAMAP	MF_00239. Cytidyl_kinase_type2. [Tree]
InterPro	IPR011892. Cyt_kin_arch. IPR011994. Cytidylate_kinase_dom. [Graphical view]
KO	K00945.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR02173. Cyt_kin_arch. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY2_BORGA

Accession

Primary (citable) accession number: Q65ZV5

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 15, 2005
Last sequence update:	October 11, 2004
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program