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Q65W08

- PGK_MANSM

UniProt

Q65W08 - PGK_MANSM

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Protein

Phosphoglycerate kinase

Gene
pgk, MS0245
Organism
Mannheimia succiniciproducens (strain MBEL55E)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei36 – 361Substrate By similarity
Binding sitei112 – 1121Substrate By similarity
Binding sitei145 – 1451Substrate By similarity
Binding sitei196 – 1961ATP By similarity
Binding sitei313 – 3131ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi342 – 3454ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBMAN221988:GHGM-249-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:MS0245
OrganismiMannheimia succiniciproducens (strain MBEL55E)
Taxonomic identifieri221988 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeBasfia
ProteomesiUP000000607: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 389389Phosphoglycerate kinaseUniRule annotationPRO_1000058011Add
BLAST

Proteomic databases

PRIDEiQ65W08.

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi221988.MS0245.

Structurei

3D structure databases

ProteinModelPortaliQ65W08.
SMRiQ65W08. Positions 2-387.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate binding By similarity
Regioni59 – 624Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiAGHPVGK.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.

Sequencei

Sequence statusi: Complete.

Q65W08-1 [UniParc]FASTAAdd to Basket

« Hide

MSVIKMTDLD LAGKRLFIRA DLNVPVKDGK VTSDARIRAT IPTLKLALEK    50
GAKVMVTSHL GRPTEGEFKP EDSLQPVVDY LKDAGFNVRL AQNYLDGVEV 100
NEGEIVVLEN VRINKGEKKN DPELGKKYAA LCDVFVMDAF GTAHRAQAST 150
YGVAEYAPVA CAGPLLAAEL DALGKALKEP QRPMLAIVGG SKVSTKLTVL 200
DSLSKIADQL IVGGGIANTF IAAEGHNVGK SLYEEDLIPE AKRLAAATNI 250
PVPVDVRVGT EFSENAPATE KSVTEVQADE SIFDIGDKSA EELAKIIKSA 300
KTILWNGPVG VFEFPNFRKG TEVISNAIAE ATANGAFSIA GGGDTLAAID 350
LFGIKDKISY ISTGGGAFLE FVEGKVLPAV EILEKRANG 389
Length:389
Mass (Da):41,241
Last modified:October 25, 2004 - v1
Checksum:i91A09D448F88E4E7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016827 Genomic DNA. Translation: AAU36852.1.
RefSeqiWP_011199427.1. NC_006300.1.
YP_087437.1. NC_006300.1.

Genome annotation databases

EnsemblBacteriaiAAU36852; AAU36852; MS0245.
GeneIDi3076778.
KEGGimsu:MS0245.
PATRICi22443916. VBIManSuc86752_0225.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016827 Genomic DNA. Translation: AAU36852.1 .
RefSeqi WP_011199427.1. NC_006300.1.
YP_087437.1. NC_006300.1.

3D structure databases

ProteinModelPortali Q65W08.
SMRi Q65W08. Positions 2-387.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 221988.MS0245.

Proteomic databases

PRIDEi Q65W08.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU36852 ; AAU36852 ; MS0245 .
GeneIDi 3076778.
KEGGi msu:MS0245.
PATRICi 22443916. VBIManSuc86752_0225.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
KOi K00927.
OMAi AGHPVGK.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci BMAN221988:GHGM-249-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of the capnophilic rumen bacterium Mannheimia succiniciproducens."
    Hong S.H., Kim J.S., Lee S.Y., In Y.H., Choi S.S., Rih J.-K., Kim C.H., Jeong H., Hur C.G., Kim J.J.
    Nat. Biotechnol. 22:1275-1281(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MBEL55E.

Entry informationi

Entry nameiPGK_MANSM
AccessioniPrimary (citable) accession number: Q65W08
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: October 25, 2004
Last modified: September 3, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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