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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Mannheimia succiniciproducens (strain MBEL55E)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciMSUC221988:G1G0A-587-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:MS0631
OrganismiMannheimia succiniciproducens (strain MBEL55E)
Taxonomic identifieri221988 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeBasfia
Proteomesi
  • UP000000607 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001979981 – 276Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST276

Interactioni

Protein-protein interaction databases

STRINGi221988.MS0631

Structurei

3D structure databases

ProteinModelPortaliQ65UX2
SMRiQ65UX2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DDT Bacteria
COG0639 LUCA
HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP
OrthoDBiPOG091H0691

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

Q65UX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATYFVGDLQ GCYDELQRLL EKVRFDPTQD LLYLVGDLVA RGDKSLECLR
60 70 80 90 100
LVKSLGKSAQ TVLGNHDLHL LATAFGIKKV KSRDRVDAIF HAEDFEELIH
110 120 130 140 150
WLRHQPLLVY NAKQNWVMTH AGISPDWDIN TAQACAKEVE NVLQQGDYCH
160 170 180 190 200
LLSQMYDSRP DLWSADLTGI ERLRYIINVF TRMRFCYRDH RLDFDCKSPV
210 220 230 240 250
DKAPEELTPW FNLSNPLYKQ VDIIFGHWAS LVDTPTPHHI YALDTGCVWN
260 270
NRMTMLRWED KQYFCQPALK DYAFNG
Length:276
Mass (Da):32,133
Last modified:October 25, 2004 - v1
Checksum:i25214040562C1090
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016827 Genomic DNA Translation: AAU37238.1
RefSeqiWP_011199810.1, NC_006300.1

Genome annotation databases

EnsemblBacteriaiAAU37238; AAU37238; MS0631
KEGGimsu:MS0631

Similar proteinsi

Entry informationi

Entry nameiAPAH_MANSM
AccessioniPrimary (citable) accession number: Q65UX2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: October 25, 2004
Last modified: March 28, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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