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Protein

Peptidase T

Gene

pepD

Organism
Mannheimia succiniciproducens (strain MBEL55E)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cleaves the N-terminal amino acid of tripeptides.SAAS annotation

Catalytic activityi

Release of the N-terminal residue from a tripeptide.SAAS annotation

Cofactori

Zn2+UniRule annotationNote: Binds 2 Zn2+ ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi80Zinc 1UniRule annotation1
Active sitei82UniRule annotation1
Metal bindingi142Zinc 1UniRule annotation1
Metal bindingi142Zinc 2UniRule annotation1
Active sitei175Proton acceptorUniRule annotation1
Metal bindingi176Zinc 2UniRule annotation1
Metal bindingi198Zinc 1UniRule annotation1
Metal bindingi381Zinc 2UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminopeptidaseSAAS annotation, Hydrolase, MetalloproteaseSAAS annotation, Protease
LigandMetal-bindingUniRule annotationSAAS annotation, ZincUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciMSUC221988:G1G0A-766-MONOMER

Protein family/group databases

MEROPSiM20.003

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidase TSAAS annotation (EC:3.4.11.4SAAS annotation)
Gene namesi
Name:pepDImported
Ordered Locus Names:MS0815Imported
OrganismiMannheimia succiniciproducens (strain MBEL55E)Imported
Taxonomic identifieri221988 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeBasfia
Proteomesi
  • UP000000607 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi221988.MS0815

Structurei

3D structure databases

ProteinModelPortaliQ65UD8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini207 – 301M20_dimerInterPro annotationAdd BLAST95

Sequence similaritiesi

Belongs to the peptidase M20B family.SAAS annotation

Phylogenomic databases

eggNOGiENOG4105D42 Bacteria
COG2195 LUCA
HOGENOMiHOG000032390
KOiK01258
OMAiGHNFHGK
OrthoDBiPOG091H04LT

Family and domain databases

CDDicd03892 M20_peptT, 1 hit
InterProiView protein in InterPro
IPR001261 ArgE/DapE_CS
IPR036264 Bact_exopeptidase_dim_dom
IPR002933 Peptidase_M20
IPR011650 Peptidase_M20_dimer
IPR010161 Peptidase_M20B
PANTHERiPTHR42994:SF1 PTHR42994:SF1, 1 hit
PfamiView protein in Pfam
PF07687 M20_dimer, 1 hit
PF01546 Peptidase_M20, 1 hit
PIRSFiPIRSF037215 Peptidase_M20B, 1 hit
SUPFAMiSSF55031 SSF55031, 1 hit
TIGRFAMsiTIGR01882 peptidase-T, 1 hit
PROSITEiView protein in PROSITE
PS00758 ARGE_DAPE_CPG2_1, 1 hit
PS00759 ARGE_DAPE_CPG2_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q65UD8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQYNEQLLER FFNYVSLDTQ SKPGAKTSPS TQGQLKLAKI LEQELYSLGL
60 70 80 90 100
DEIEVSKHGI VTALLPGNIE NSPTIGLIAH LDTSPQCSGK NVKPEVIENY
110 120 130 140 150
RGGDIALGLG DEFISPVTFT FLHKLVGKTL IVTDGTTLLG ADNKAGIAEI
160 170 180 190 200
MTALSQLKES SVPRCHIRVA FTPDEEIGLG MKFFPIEKFS CDWAYTIDGG
210 220 230 240 250
AVGELEYENF NAAGATVTIF GRAIHPGSAK DKMVNALTLA CEFQQGFPTD
260 270 280 290 300
EVPEKTEEKQ GFFHLNSFHG DIEKVELHYL IRDFDKQAFT QRKAFLEKWV
310 320 330 340 350
DEFNCRKQLK EPVKVTITDN YYNMYDTVSK VPQSIELADS AMKACGIVPI
360 370 380 390 400
HQPIRGGTDG AWLAEKGLAC PNIFTGGYNF HSKHELITLE GMCSAVDVIM

KIAQLAVK
Length:408
Mass (Da):45,022
Last modified:October 25, 2004 - v1
Checksum:iACD9956C3A275194
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016827 Genomic DNA Translation: AAU37422.1
RefSeqiWP_011199994.1, NC_006300.1

Genome annotation databases

EnsemblBacteriaiAAU37422; AAU37422; MS0815
KEGGimsu:MS0815

Similar proteinsi

Entry informationi

Entry nameiQ65UD8_MANSM
AccessioniPrimary (citable) accession number: Q65UD8
Entry historyiIntegrated into UniProtKB/TrEMBL: October 25, 2004
Last sequence update: October 25, 2004
Last modified: February 28, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health