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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Mannheimia succiniciproducens (strain MBEL55E)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei138UniRule annotation1
Active sitei545UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotation
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciMSUC221988:G1G0A-954-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:MS1017Imported
OrganismiMannheimia succiniciproducens (strain MBEL55E)Imported
Taxonomic identifieri221988 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeBasfia
Proteomesi
  • UP000000607 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi221988.MS1017

Structurei

3D structure databases

ProteinModelPortaliQ65TT6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238648
KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q65TT6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEEYLMMRN NINMLGRFLG ETIQEAQGDD ILELIENIRV LSRNSRSGDD
60 70 80 90 100
KARAALLDTL STISADNIIP VARAFSQFLN LTNVAEQYQT MSRSHEDKVS
110 120 130 140 150
AERSTAALFA RLKEQHVSQE EIIKTVQKLL IEIVLTAHPT EVTRRSLMHK
160 170 180 190 200
QVEINKCLAQ LDHTDLTAEE QKNIEYKLLR LIAEAWHTNE IRTNRPTPLE
210 220 230 240 250
EAKWGFAVIE NSLWEGLPAF IRKLNDAAVE HLNYALPVDL TPVRFSSWMG
260 270 280 290 300
GDRDGNPFVT AKITREALQL ARWKAADLFL TDIQELCDEL SMTQCTAEFR
310 320 330 340 350
EKYGDHLEPY RVVVKDLRSK LKNTLDYYND ILAGRIPPFK QDEIISEDQQ
360 370 380 390 400
LWQPLYDCYQ SLTACGMRII ANGLLLDTLR RVRCFGVTLL RLDIRQESTR
410 420 430 440 450
HSDAIGEITR YIGLGDYSQW TEDDKQAFLI RELSSRRPLI PHNWTPSEHT
460 470 480 490 500
REILDTCKVI AKQPEGVISC YIISMARTAS DVLAVHLLLK EAGISYHLPV
510 520 530 540 550
VPLFETLDDL DASKEVMTQL FNVGWYRGVI KNRQMIMIGY SDSAKDAGMM
560 570 580 590 600
AASWAQYRAQ DALVKLCEQT GIELTLFHGR GGTVGRGGAP AHAALLSQPP
610 620 630 640 650
RSLKNGLRVT EQGEMIRFKL GLPAIAAESL DLYASAILEA NLLPPPEPKA
660 670 680 690 700
SWCRVMDELA VASCEIYRNV VRGDKDFVPY FRSATPEQEL AKLPLGSRPA
710 720 730 740 750
KRNPNGGVES LRAIPWIFAW MQNRLMLPAW LGAGASIRQA MESGKAAVIE
760 770 780 790 800
EMCNHWPFFN TRIGMLEMVF SKTDSWLSEY YDQRLVKKEL WYLGESLRKQ
810 820 830 840 850
LSEDIATVLR LSGKGDQLMS DLPWVAESIA LRNVYTDPLN LLQVELLRRL
860 870 880
RADPEHPNPD IEQALMITIT GIAAGMRNTG
Length:880
Mass (Da):99,613
Last modified:October 25, 2004 - v1
Checksum:iB67AA9DE11D8C59D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016827 Genomic DNA Translation: AAU37624.1
RefSeqiWP_011200194.1, NC_006300.1

Genome annotation databases

EnsemblBacteriaiAAU37624; AAU37624; MS1017
KEGGimsu:MS1017

Similar proteinsi

Entry informationi

Entry nameiQ65TT6_MANSM
AccessioniPrimary (citable) accession number: Q65TT6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 25, 2004
Last sequence update: October 25, 2004
Last modified: March 28, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health