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Q65TI0

- GLGB_MANSM

UniProt

Q65TI0 - GLGB_MANSM

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Protein

1,4-alpha-glucan branching enzyme GlgB

Gene

glgB

Organism
Mannheimia succiniciproducens (strain MBEL55E)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.UniRule annotation

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei405 – 4051NucleophileUniRule annotation
Active sitei458 – 4581Proton donorUniRule annotation

GO - Molecular functioni

  1. 1,4-alpha-glucan branching enzyme activity Source: UniProtKB-HAMAP
  2. cation binding Source: InterPro
  3. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

BioCyciBMAN221988:GHGM-1159-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgBUniRule annotation (EC:2.4.1.18UniRule annotation)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferaseUniRule annotation
Alpha-(1->4)-glucan branching enzymeUniRule annotation
Glycogen branching enzymeUniRule annotation
Short name:
BEUniRule annotation
Gene namesi
Name:glgBUniRule annotation
Ordered Locus Names:MS1123
OrganismiMannheimia succiniciproducens (strain MBEL55E)
Taxonomic identifieri221988 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeBasfia
ProteomesiUP000000607: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7297291,4-alpha-glucan branching enzyme GlgBPRO_0000188714Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi221988.MS1123.

Structurei

3D structure databases

ProteinModelPortaliQ65TI0.
SMRiQ65TI0. Positions 117-725.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0296.
HOGENOMiHOG000283037.
KOiK00700.
OMAiAKLLFMG.
OrthoDBiEOG6JX7GT.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPiMF_00685. GlgB.
InterProiIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFiPIRSF000463. GlgB. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsiTIGR01515. branching_enzym. 1 hit.

Sequencei

Sequence statusi: Complete.

Q65TI0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKKLVAQSVI DAFFDGTHSD PFAVLGMHET HNGIEIRVLL PEAHRVIVID
60 70 80 90 100
KETHKAVVEL ELVDERGFFN AIVPKANQFF AYELQVYWGK ESQILEDPYR
110 120 130 140 150
FHPMINELDN WLLAEGSHLR PYEVLGAHFV EYDNVAGVNF RVWAPNAKRV
160 170 180 190 200
SVVGDFNYWD GRRHPMRFHP ASGIWELFLP KVALGQLYKF ELIDSNNQLR
210 220 230 240 250
LKADPYAFAA QLRPDTASQV SALPEIVEMT EKRRAANQSD KPISIYEVHL
260 270 280 290 300
GSWRRNLENN FWLDYDEIAD ELIPYVKEMG FTHIELLPIS EYPFDGSWGY
310 320 330 340 350
QPLGLYAPTS RFGTPDGFKR LIEKAHESGI NVILDWVPGH FPSDTHGLAA
360 370 380 390 400
FDGTSLYEYA DPKEGYHQDW NTLIYNYGRH EVKNYLSGNA LYWVERFGLD
410 420 430 440 450
GLRVDAVASM IYRDYSRRDG EWVPNQYGGR ENLEAIEFLK HTNYVLGTEL
460 470 480 490 500
PGVAAIAEES TSFPGVTLPP EHGGLGFHYK WNMGWMNDTL EYMKLDPVYR
510 520 530 540 550
QYHHGKMTFA MLYQYSENFV LPLSHDEVVH GKGSLITKMS GDTWQKFANL
560 570 580 590 600
RAYYGYMWAF PGKKLLFMGN EFAQGREWNY QESLDWFLLD DGQGGGWHSG
610 620 630 640 650
VQRLVKDLNK TYQNQTALFE LDTNPQGFEW LVVDDNQNSV FAFERRSKSG
660 670 680 690 700
EVIIVVSNFT PVPRDNYRIG VNEPGKYEEI LNTDSAYYKG SNLGNYGEVI
710 720
AEEIENHGKA QSISVMVPPL ATVYLRLKK
Length:729
Mass (Da):83,760
Last modified:October 25, 2004 - v1
Checksum:i723DDFB52E751887
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016827 Genomic DNA. Translation: AAU37730.1.
RefSeqiWP_011200298.1. NC_006300.1.
YP_088315.1. NC_006300.1.

Genome annotation databases

EnsemblBacteriaiAAU37730; AAU37730; MS1123.
GeneIDi3075873.
KEGGimsu:MS1123.
PATRICi22445593. VBIManSuc86752_1028.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016827 Genomic DNA. Translation: AAU37730.1 .
RefSeqi WP_011200298.1. NC_006300.1.
YP_088315.1. NC_006300.1.

3D structure databases

ProteinModelPortali Q65TI0.
SMRi Q65TI0. Positions 117-725.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 221988.MS1123.

Protein family/group databases

CAZyi CBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU37730 ; AAU37730 ; MS1123 .
GeneIDi 3075873.
KEGGi msu:MS1123.
PATRICi 22445593. VBIManSuc86752_1028.

Phylogenomic databases

eggNOGi COG0296.
HOGENOMi HOG000283037.
KOi K00700.
OMAi AKLLFMG.
OrthoDBi EOG6JX7GT.

Enzyme and pathway databases

UniPathwayi UPA00164 .
BioCyci BMAN221988:GHGM-1159-MONOMER.

Family and domain databases

Gene3Di 2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPi MF_00685. GlgB.
InterProi IPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view ]
PANTHERi PTHR10357. PTHR10357. 1 hit.
Pfami PF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view ]
PIRSFi PIRSF000463. GlgB. 1 hit.
SUPFAMi SSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsi TIGR01515. branching_enzym. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of the capnophilic rumen bacterium Mannheimia succiniciproducens."
    Hong S.H., Kim J.S., Lee S.Y., In Y.H., Choi S.S., Rih J.-K., Kim C.H., Jeong H., Hur C.G., Kim J.J.
    Nat. Biotechnol. 22:1275-1281(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MBEL55E.

Entry informationi

Entry nameiGLGB_MANSM
AccessioniPrimary (citable) accession number: Q65TI0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: October 25, 2004
Last modified: October 29, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3