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Q65TC2

- G6PI_MANSM

UniProt

Q65TC2 - G6PI_MANSM

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Mannheimia succiniciproducens (strain MBEL55E)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 1 (25 Oct 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei355 – 3551Proton donorUniRule annotation
    Active sitei387 – 3871UniRule annotation
    Active sitei515 – 5151UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciBMAN221988:GHGM-1216-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:MS1181
    OrganismiMannheimia succiniciproducens (strain MBEL55E)
    Taxonomic identifieri221988 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeBasfia
    ProteomesiUP000000607: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 549549Glucose-6-phosphate isomerasePRO_0000180670Add
    BLAST

    Proteomic databases

    PRIDEiQ65TC2.

    Interactioni

    Protein-protein interaction databases

    STRINGi221988.MS1181.

    Structurei

    3D structure databases

    ProteinModelPortaliQ65TC2.
    SMRiQ65TC2. Positions 30-549.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000261370.
    KOiK01810.
    OMAiNCHFVAN.
    OrthoDBiEOG64R61J.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q65TC2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQNINPTSTA AWKALEAHKG TLENTTINDL FQQEKNRFAD YSLTFNNEIL    50
    VDFSKNKITR ETLNLLRRLA KECALDEAKE AMFSGEKINR TENRAVLHTA 100
    LRNRSNTAVL VDGKDVMPEV NEVLAKMKAF SERVISGEWK GYTGKAITDV 150
    VNIGIGGSDL GPYMVTEALR PYKNHLNMHF VSNVDGTHIA EVFKKTNPET 200
    TLFLVASKTF TTQETMTNAK SARDWFLATA KDEKHVAKHF AALSTNAAEV 250
    EKFGIDTDNM FGFWDWVGGR YSLWSAIGLS IILSVGFENF EALLSGAHEM 300
    DKHFRNTPIE QNIPATLALV GLWNTNFQGA QTEAILPYDQ YMHRFAAYFQ 350
    QGNMESNGKY VGRDGKVISN YQTGPIIWGE PGTNGQHAFY QLIHQGTTLI 400
    PCDFIAPAKT HNPLADHHNK LLSNFFAQTE ALAFGKTKET VEAEFLKAGK 450
    SLDEVKDVVP FKVFAGNKPT NSILLQEITP FSLGALIAMY EHKIFVQGVI 500
    FNIFSFDQWG VELGKQLANR ILPELSGDEQ VTGHDSSTNG LINQFKAWR 549
    Length:549
    Mass (Da):61,349
    Last modified:October 25, 2004 - v1
    Checksum:iAE66442E35C00F74
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016827 Genomic DNA. Translation: AAU37788.1.
    RefSeqiYP_088373.1. NC_006300.1.

    Genome annotation databases

    EnsemblBacteriaiAAU37788; AAU37788; MS1181.
    GeneIDi3076611.
    KEGGimsu:MS1181.
    PATRICi22445693. VBIManSuc86752_1078.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016827 Genomic DNA. Translation: AAU37788.1 .
    RefSeqi YP_088373.1. NC_006300.1.

    3D structure databases

    ProteinModelPortali Q65TC2.
    SMRi Q65TC2. Positions 30-549.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 221988.MS1181.

    Proteomic databases

    PRIDEi Q65TC2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAU37788 ; AAU37788 ; MS1181 .
    GeneIDi 3076611.
    KEGGi msu:MS1181.
    PATRICi 22445693. VBIManSuc86752_1078.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000261370.
    KOi K01810.
    OMAi NCHFVAN.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci BMAN221988:GHGM-1216-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of the capnophilic rumen bacterium Mannheimia succiniciproducens."
      Hong S.H., Kim J.S., Lee S.Y., In Y.H., Choi S.S., Rih J.-K., Kim C.H., Jeong H., Hur C.G., Kim J.J.
      Nat. Biotechnol. 22:1275-1281(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MBEL55E.

    Entry informationi

    Entry nameiG6PI_MANSM
    AccessioniPrimary (citable) accession number: Q65TC2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 29, 2005
    Last sequence update: October 25, 2004
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3