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Q65TC2

- G6PI_MANSM

UniProt

Q65TC2 - G6PI_MANSM

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Mannheimia succiniciproducens (strain MBEL55E)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei355 – 3551Proton donorUniRule annotation
Active sitei387 – 3871UniRule annotation
Active sitei515 – 5151UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciBMAN221988:GHGM-1216-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:MS1181
OrganismiMannheimia succiniciproducens (strain MBEL55E)
Taxonomic identifieri221988 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeBasfia
ProteomesiUP000000607: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 549549Glucose-6-phosphate isomerasePRO_0000180670Add
BLAST

Proteomic databases

PRIDEiQ65TC2.

Interactioni

Protein-protein interaction databases

STRINGi221988.MS1181.

Structurei

3D structure databases

ProteinModelPortaliQ65TC2.
SMRiQ65TC2. Positions 30-549.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiNCHFVAN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q65TC2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQNINPTSTA AWKALEAHKG TLENTTINDL FQQEKNRFAD YSLTFNNEIL
60 70 80 90 100
VDFSKNKITR ETLNLLRRLA KECALDEAKE AMFSGEKINR TENRAVLHTA
110 120 130 140 150
LRNRSNTAVL VDGKDVMPEV NEVLAKMKAF SERVISGEWK GYTGKAITDV
160 170 180 190 200
VNIGIGGSDL GPYMVTEALR PYKNHLNMHF VSNVDGTHIA EVFKKTNPET
210 220 230 240 250
TLFLVASKTF TTQETMTNAK SARDWFLATA KDEKHVAKHF AALSTNAAEV
260 270 280 290 300
EKFGIDTDNM FGFWDWVGGR YSLWSAIGLS IILSVGFENF EALLSGAHEM
310 320 330 340 350
DKHFRNTPIE QNIPATLALV GLWNTNFQGA QTEAILPYDQ YMHRFAAYFQ
360 370 380 390 400
QGNMESNGKY VGRDGKVISN YQTGPIIWGE PGTNGQHAFY QLIHQGTTLI
410 420 430 440 450
PCDFIAPAKT HNPLADHHNK LLSNFFAQTE ALAFGKTKET VEAEFLKAGK
460 470 480 490 500
SLDEVKDVVP FKVFAGNKPT NSILLQEITP FSLGALIAMY EHKIFVQGVI
510 520 530 540
FNIFSFDQWG VELGKQLANR ILPELSGDEQ VTGHDSSTNG LINQFKAWR
Length:549
Mass (Da):61,349
Last modified:October 25, 2004 - v1
Checksum:iAE66442E35C00F74
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016827 Genomic DNA. Translation: AAU37788.1.
RefSeqiYP_088373.1. NC_006300.1.

Genome annotation databases

EnsemblBacteriaiAAU37788; AAU37788; MS1181.
GeneIDi3076611.
KEGGimsu:MS1181.
PATRICi22445693. VBIManSuc86752_1078.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016827 Genomic DNA. Translation: AAU37788.1 .
RefSeqi YP_088373.1. NC_006300.1.

3D structure databases

ProteinModelPortali Q65TC2.
SMRi Q65TC2. Positions 30-549.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 221988.MS1181.

Proteomic databases

PRIDEi Q65TC2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU37788 ; AAU37788 ; MS1181 .
GeneIDi 3076611.
KEGGi msu:MS1181.
PATRICi 22445693. VBIManSuc86752_1078.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OMAi NCHFVAN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci BMAN221988:GHGM-1216-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of the capnophilic rumen bacterium Mannheimia succiniciproducens."
    Hong S.H., Kim J.S., Lee S.Y., In Y.H., Choi S.S., Rih J.-K., Kim C.H., Jeong H., Hur C.G., Kim J.J.
    Nat. Biotechnol. 22:1275-1281(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MBEL55E.

Entry informationi

Entry nameiG6PI_MANSM
AccessioniPrimary (citable) accession number: Q65TC2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: October 25, 2004
Last modified: October 29, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3