Q65S72 (DCD_MANSM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	MS1581

Organism

Mannheimia succiniciproducens (strain MBEL55E) [Complete proteome] [HAMAP]

Taxonomic identifier

221988 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Basfia › Mannheimia succiniciproducens

Protein attributes

Sequence length	194 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 194	194	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000009749

Sequences

	Sequence		Length	Mass (Da)
	Q65S72 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: BD89F99C6ACFC943	FASTA	194	21,959
	10 20 30 40 50 60 MRLCDTDIER YLDEGIIEIT PRPGNEKING ATIDLRLGNS FRVFRDYSAP YIDVSGPREE 70 80 90 100 110 120 VSAQLDRVMS DEIIIRDDEP FFLHPGVLAL ATTLESVRLP DNIIGWLDGR SSLARLGLMV 130 140 150 160 170 180 HVTAHRIDPG WEGRIVLEFY NSGKLPLALR PNMIIGALSF EILSNHAARP YNRRRDAKYK 190 NQQSAVASRI NQDE

References

[1]

"The genome sequence of the capnophilic rumen bacterium Mannheimia succiniciproducens." Hong S.H., Kim J.S., Lee S.Y., In Y.H., Choi S.S., Rih J.-K., Kim C.H., Jeong H., Hur C.G., Kim J.J. Nat. Biotechnol. 22:1275-1281(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MBEL55E.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016827 Genomic DNA. Translation: AAU38188.1.
RefSeq	YP_088773.1. NC_006300.1.
3D structure databases
HSSP	HSSP built from PDB template 1XS1 based on UniProtKB P28248.
ProteinModelPortal	Q65S72.
SMR	Q65S72. Positions 1-193.
ModBase	Search...
Protein-protein interaction databases
STRING	221988.MS1581.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAU38188; AAU38188; MS1581.
GeneID	3076426.
KEGG	msu:MS1581.
PATRIC	22446449. VBIManSuc86752_1442.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228601.
KO	K01494.
OMA	RQDAKYK.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	BMAN221988:GHGM-1574-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR010550. dCTP_deam_bac. [Graphical view]
Pfam	PF06559. DCD. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_MANSM

Accession

Primary (citable) accession number: Q65S72

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 25, 2004
Last modified:	May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program