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Q65R09 (GLPB_MANSM) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Anaerobic glycerol-3-phosphate dehydrogenase subunit B

Short name=Anaerobic G-3-P dehydrogenase subunit B
Short name=Anaerobic G3Pdhase B
EC=1.1.5.3
Gene names
Name:glpB
Ordered Locus Names:MS1994
OrganismMannheimia succiniciproducens (strain MBEL55E) [Complete proteome] [HAMAP]
Taxonomic identifier221988 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeBasfia

Protein attributes

Sequence length431 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor By similarity. HAMAP-Rule MF_00753

Catalytic activity

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol. HAMAP-Rule MF_00753

Cofactor

FMN By similarity. HAMAP-Rule MF_00753

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1. HAMAP-Rule MF_00753

Subunit structure

Composed of a catalytic GlpA/B dimer and of membrane bound GlpC By similarity.

Sequence similarities

Belongs to the anaerobic G-3-P dehydrogenase subunit B family.

Ontologies

Keywords
   LigandFlavoprotein
FMN
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycerol catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionsn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 431431Anaerobic glycerol-3-phosphate dehydrogenase subunit B HAMAP-Rule MF_00753
PRO_0000258903

Sequences

Sequence LengthMass (Da)Tools
Q65R09 [UniParc].

Last modified October 25, 2004. Version 1.
Checksum: 6C56478C9A41F3CA

FASTA43147,213
        10         20         30         40         50         60 
MNFDVVIIGA GIAGLTCGLT LQEKGVRCAI INNGQAALDF SSGSMDLLSR LPNGSTVDSF 

        70         80         90        100        110        120 
AQSYAALAQQ SPNHPYVILG KDVVLDKIQQ FETLAKSLNL SLVGSSDKNH KRVTALGGLR 

       130        140        150        160        170        180 
GTWLSPNSVP TVSLEGKFPH DNIVLLGIEG YHDFQPQLLA DNLKQNPQFA HCEITTNFLH 

       190        200        210        220        230        240 
IPELDHLRQN SREFRSVNIA QVLEYKLSFN NLVDEIKQAV GNAKAAFLPA CFGLDDQSFF 

       250        260        270        280        290        300 
ESLKQATGIE LYELPTLPPS LLGIRQHRQL RHRFEKLGGV MFNGDRALRS EFEGNKVARI 

       310        320        330        340        350        360 
FTQLHLENAV TAKYFVLASG GFFSNGLVSE FEEIYEPLFR SDIVKTERFN ATDRFSWISK 

       370        380        390        400        410        420 
RFADPQPYQS AGVVINAECQ VQKDGNNVEN LFAIGAVIGG YNGIELGCGS GVAVTTALKV 

       430 
ADNIIAKESS N 

« Hide

References

[1]"The genome sequence of the capnophilic rumen bacterium Mannheimia succiniciproducens."
Hong S.H., Kim J.S., Lee S.Y., In Y.H., Choi S.S., Rih J.-K., Kim C.H., Jeong H., Hur C.G., Kim J.J.
Nat. Biotechnol. 22:1275-1281(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MBEL55E.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016827 Genomic DNA. Translation: AAU38601.1.
RefSeqYP_089186.1. NC_006300.1.

3D structure databases

ProteinModelPortalQ65R09.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING221988.MS1994.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAU38601; AAU38601; MS1994.
GeneID3075472.
KEGGmsu:MS1994.
PATRIC22447233. VBIManSuc86752_1823.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3075.
HOGENOMHOG000278489.
KOK00112.
OMAFRSVNIS.
OrthoDBEOG6K6V62.
ProtClustDBPRK05329.

Enzyme and pathway databases

BioCycBMAN221988:GHGM-2048-MONOMER.
UniPathwayUPA00618; UER00673.

Family and domain databases

HAMAPMF_00753. Glycerol3P_GlpB.
InterProIPR003953. FAD_bind_dom.
IPR009158. G3P_DH_GlpB_su.
[Graphical view]
PfamPF00890. FAD_binding_2. 1 hit.
[Graphical view]
PIRSFPIRSF000141. Anaerobic_G3P_dh. 1 hit.
TIGRFAMsTIGR03378. glycerol3P_GlpB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLPB_MANSM
AccessionPrimary (citable) accession number: Q65R09
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 25, 2004
Last modified: February 19, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways