Reviewed, UniProtKB/Swiss-Prot Q65P47 (GLMM_BACLD)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	BLi00203, BL02703

Organism

Bacillus licheniformis (strain DSM 13 / ATCC 14580) [Complete proteome] [HAMAP]

Taxonomic identifier

279010 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	448 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity.
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Post-translational modification	Activated by phosphorylation By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 448	448	Phosphoglucosamine mutase HAMAP MF_01554		PRO_0000147845
Sites
	Active site	100	1	Phosphoserine intermediate By similarity
	Metal binding	100	1	Magnesium; via phosphate group By similarity
	Metal binding	240	1	Magnesium By similarity
	Metal binding	242	1	Magnesium By similarity
	Metal binding	244	1	Magnesium By similarity
Amino acid modifications
	Modified residue	100	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q65P47-1 [UniParc]. Last modified December 20, 2005. Version 2. Checksum: 5177B0EE99310578	FASTA	448	48,198
	10 20 30 40 50 60 MGKYFGTDGV RGVANSELTP ELAFKVGRFG GYVLTKDKER PKVLIGRDTR ISGHMLEGAL 70 80 90 100 110 120 VAGLLSIGAE VMRLGVISTP GVAYLTKAMD AEAGVMISAS HNPVQDNGIK FFGGDGFKLS 130 140 150 160 170 180 DEQELEIERL MDQPEDHLPR PVGADLGMVN DYFEGGQKYL QFLKQSADED FTGIHVALDC 190 200 210 220 230 240 AHGATSSLAT HLFADLDADV STMGTSPNGL NINDGVGSTH PEALAEFVKE KGADVGMAFD 250 260 270 280 290 300 GDGDRLIAVD EKGNIVDGDQ IMYICAKYLK SEGRLTDNTV VSTVMSNLGF YKALEAEGIK 310 320 330 340 350 360 SVQTAVGDRY VVEAMKKGGF TLGGEQSGHL IFLDYNTTGD GLLSAIMLMN TIKMTGKPLS 370 380 390 400 410 420 ELAAEMQKFP QLLLNVKVTD KHKVTENEKV KAVIEEVEKE MNGDGRILVR PSGTEPLVRV 430 440 MAEAKTKELC EKYVGRIADV VKAEMGAE

References

[1]

"The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential." Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P., Baeumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G. J. Mol. Microbiol. Biotechnol. 7:204-211(2004) [PubMed: 15383718] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species." Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J., Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B., Rasmussen M.D., Andersen J.T., Joergensen P.L., Larsen T.S., Sorokin A., Bolotin A., Lapidus A. , Galleron N., Ehrlich S.D., Berka R.M. Genome Biol. 5:RESEARCH077.1-RESEARCH077.12(2004) [PubMed: 15461803] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017333 Genomic DNA. Translation: AAU39167.1. Different initiation. CP000002 Genomic DNA. Translation: AAU21822.1.
RefSeq	YP_077460.1. YP_089860.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q65P47.
Genome annotation databases
GeneID	3028093. 3099927.
GenomeReviews	Gene locus BLi00203 in contig AE017333_GR. Gene locus BL02703 in contig CP000002_GR.
KEGG	bld:BLi00203. bli:BL02703.
NMPDR	fig|279010.5.peg.1781.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q65P47.
OMA	STHPEAM.
Enzyme and pathway databases
BioCyc	BLIC279010:BL02703-MON.
Family and domain databases
HAMAP	MF_01554. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_BACLD

Accession

Primary (citable) accession number: Q65P47
Secondary accession number(s): Q62ZI6

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	December 20, 2005
Last modified:	November 3, 2009
This is version 38 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)