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Protein

Probable 5-dehydro-4-deoxyglucarate dehydratase

Gene

BLi00284

Organism
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

5-dehydro-4-deoxy-D-glucarate = 2,5-dioxopentanoate + H2O + CO2.UniRule annotation

Pathwayi: D-glucarate degradation

This protein is involved in step 2 of the subpathway that synthesizes 2,5-dioxopentanoate from D-glucarate.UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Probable 5-dehydro-4-deoxyglucarate dehydratase (BLi00284)
This subpathway is part of the pathway D-glucarate degradation, which is itself part of Carbohydrate acid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 2,5-dioxopentanoate from D-glucarate, the pathway D-glucarate degradation and in Carbohydrate acid metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase

Enzyme and pathway databases

BioCyciBLIC279010:G1G12-286-MONOMER
UniPathwayiUPA00564; UER00628

Names & Taxonomyi

Protein namesi
Recommended name:
Probable 5-dehydro-4-deoxyglucarate dehydrataseUniRule annotation (EC:4.2.1.41UniRule annotation)
Alternative name(s):
5-keto-4-deoxy-glucarate dehydrataseUniRule annotation
Short name:
KDGDHUniRule annotation
Gene namesi
Ordered Locus Names:BLi00284, BL01645
OrganismiBacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Taxonomic identifieri279010 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000000606 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000453991 – 308Probable 5-dehydro-4-deoxyglucarate dehydrataseAdd BLAST308

Proteomic databases

PRIDEiQ65NX1

Interactioni

Protein-protein interaction databases

STRINGi279010.BLi00284

Structurei

3D structure databases

ProteinModelPortaliQ65NX1
SMRiQ65NX1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DapA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105UVJ Bacteria
COG0329 LUCA
HOGENOMiHOG000173605
KOiK01707
OMAiRNRKKGY

Family and domain databases

CDDicd00951 KDGDH, 1 hit
Gene3Di3.20.20.70, 1 hit
HAMAPiMF_00694 KDGDH, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR002220 DapA-like
IPR017655 Dehydro-deoxyglucarate_dehyd
PANTHERiPTHR12128 PTHR12128, 1 hit
PfamiView protein in Pfam
PF00701 DHDPS, 1 hit
PIRSFiPIRSF001365 DHDPS, 1 hit
SMARTiView protein in SMART
SM01130 DHDPS, 1 hit
TIGRFAMsiTIGR03249 KdgD, 1 hit

Sequencei

Sequence statusi: Complete.

Q65NX1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQLRKAPEG ILGFPVAPFN REGKLEEEAL YENIRFLLDE GLEAVFIACG
60 70 80 90 100
SGEFQSLSTK EYEQMVEIAV SAADGKVPVY TGVGGNLSTA LEWARISEEK
110 120 130 140 150
GADGYLILPP YLIHGEQEGL YQYTKTIIES TDLNAIIYQR DNAVLTLEQI
160 170 180 190 200
QRLTDLEQLV GLKDGIGDMA LNISLSYTIG DRLGWLNGMP MAEVTMPAYA
210 220 230 240 250
PIGFTSYSSA ISNYIPHISR MFYEALLNGN DRLVKEIYEQ VIIPINEIRK
260 270 280 290 300
LRKGYAVSLI KAGMEIMGLH VKNTARPPIV PVEKEHCRQL ENILKNAMAR

YPKTTAAL
Length:308
Mass (Da):34,251
Last modified:October 25, 2004 - v1
Checksum:i0F642A9A2E4FA5AB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000002 Genomic DNA Translation: AAU21891.2
AE017333 Genomic DNA Translation: AAU39243.1
RefSeqiWP_011197512.1, NC_006322.1

Genome annotation databases

EnsemblBacteriaiAAU21891; AAU21891; BL01645
AAU39243; AAU39243; BLi00284
GeneIDi3028847
KEGGibld:BLi00284
bli:BL01645
PATRICifig|279010.13.peg.269

Similar proteinsi

Entry informationi

Entry nameiKDGD_BACLD
AccessioniPrimary (citable) accession number: Q65NX1
Secondary accession number(s): Q62ZB7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 25, 2004
Last modified: May 23, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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