ID   Q65NE7_BACLD            Unreviewed;       572 AA.
AC   Q65NE7; Q62YU8;
DT   25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2004, sequence version 1.
DT   27-MAR-2024, entry version 113.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:AAU22060.1};
GN   Name=tlpA {ECO:0000313|EMBL:AAU22060.1};
GN   OrderedLocusNames=BL01850 {ECO:0000313|EMBL:AAU22060.1};
OS   Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 /
OS   NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46).
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=279010 {ECO:0000313|EMBL:AAU22060.1, ECO:0000313|Proteomes:UP000000606};
RN   [1] {ECO:0000313|EMBL:AAU22060.1, ECO:0000313|Proteomes:UP000000606}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB
RC   9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46
RC   {ECO:0000313|Proteomes:UP000000606};
RX   PubMed=15461803; DOI=10.1186/gb-2004-5-10-r77;
RA   Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J.,
RA   Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B.,
RA   Rasmussen M.D., Andersen J.T., Jorgensen P.L., Larsen T.S., Sorokin A.,
RA   Bolotin A., Lapidus A., Galleron N., Ehrlich S.D., Berka R.M.;
RT   "Complete genome sequence of the industrial bacterium Bacillus
RT   licheniformis and comparisons with closely related Bacillus species.";
RL   Genome Biol. 5:R77.1-R77.12(2004).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000002; AAU22060.1; -; Genomic_DNA.
DR   RefSeq; WP_003178933.1; NC_006322.1.
DR   AlphaFoldDB; Q65NE7; -.
DR   STRING; 279010.BL01850; -.
DR   GeneID; 66217388; -.
DR   KEGG; bli:BL01850; -.
DR   PATRIC; fig|279010.13.peg.448; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_27_9; -.
DR   Proteomes; UP000000606; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR024478; HlyB_4HB_MCP.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF12729; 4HB_MCP_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000606};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        189..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          213..265
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          284..555
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   COILED          75..129
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   572 AA;  62261 MW;  4B06146888CA50F5 CRC64;
     MNLLRNIKIR SKLFVIIIIS ALALSIVGIQ GVGGLSKLSK GSEMIYQDQL IPNQLFARLK
     ANNLDLDTYK FELMVTKDSD RNETLQKNIK EKNEENNTLM EKIDQLKLMD NVSEKYESFK
     SEYKKLQDIS SQMLSLAVKN ENDKAYDVYL KEMEPQRETV NQLIEDIQTL NADNAKTIYQ
     RDSKEAGSII TLLIIVIAAS LVLSISIGLL MTRLITKPIK DIQALFAETE QGDFTVKGTY
     QSKDELGLLT ASFNKMVAGV RSIIETVGET SHQVASSSQE LSASADESTK ASEYISTTIQ
     ELAVGSDQQV ESVENSRTVI KGMTEFAGRI SSSAEKAAAT ADQTAKMSLE GTKAIDKVSA
     QMQSINETVV SLSEAFKHLT ERSNEIGNIT EVITSIAEQT NLLALNAAIE AARAGEQGKG
     FAVVADEVRK LAEQSAQSAE QITRLITIIQ NDTKQTMNSV ISATGEVKEG LVVVHEAGGA
     FQKIENSITE VVTQINDVTN LVKNLTAGTS EIETAISGVK EVAETAAGST QTVSAATQEQ
     LASMEEIAAA SQILAQNAEE LQHLIQKFKI KD
//