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Q65N57

- Q65N57_BACLD

UniProt

Q65N57 - Q65N57_BACLD

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Protein

Alanine racemase

Gene

alr1

Organism
Bacillus licheniformis (strain DSM 13 / ATCC 14580)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei42 – 421Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei140 – 1401SubstrateUniRule annotation
Active sitei269 – 2691Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei316 – 3161Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alr1Imported
Ordered Locus Names:BLi00551Imported
OrganismiBacillus licheniformis (strain DSM 13 / ATCC 14580)Imported
Taxonomic identifieri279010 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000000608: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei42 – 421N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ65N57.
SMRiQ65N57. Positions 6-385.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000031444.
KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q65N57-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMSLKPFYRK TWAEIDLTAL KENVRNMKRH IGEHVRLMAV VKANAYGHGD
60 70 80 90 100
AQVAKAALAE GASILAVALL DEALSLRAQG IEEPILVLGA VPTEYASIAA
110 120 130 140 150
EKRIIVTGYS VGWLKDVLGF LNEAEAPLEY HLKIDTGMGR LGCKTEEEIK
160 170 180 190 200
EMMEMTESND KLNCTGVFTH FATADEKDTD YFNMQLDRFK ELISPLPLDR
210 220 230 240 250
LMVHSSNSAA GLRFREQLFN AVRFGIGMYG LAPSTEIKDE LPFRLREVFS
260 270 280 290 300
LHTELTHVKK IKKGESVSYG ATYTAQRDEW IGTVPVGYAD GWLRRLAGTE
310 320 330 340 350
VLIDGKRQKI AGRICMDQFM ISLAEEYPVG TKVTLIGKQK DEWISVDEIA
360 370 380 390
QNLQTINYEI TCMISSRVPR MFLENGSIME IRNPILPDQS
Length:390
Mass (Da):43,743
Last modified:October 25, 2004 - v1
Checksum:i17678550ED2D3C02
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017333 Genomic DNA. Translation: AAU39507.1.
RefSeqiWP_011201566.1. NC_006322.1.
YP_006711978.1. NC_006322.1.

Genome annotation databases

EnsemblBacteriaiAAU39507; AAU39507; BLi00551.
GeneIDi3097603.
KEGGibld:BLi00551.
PATRICi18946619. VBIBacLic203714_0548.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017333 Genomic DNA. Translation: AAU39507.1 .
RefSeqi WP_011201566.1. NC_006322.1.
YP_006711978.1. NC_006322.1.

3D structure databases

ProteinModelPortali Q65N57.
SMRi Q65N57. Positions 6-385.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU39507 ; AAU39507 ; BLi00551 .
GeneIDi 3097603.
KEGGi bld:BLi00551.
PATRICi 18946619. VBIBacLic203714_0548.

Phylogenomic databases

HOGENOMi HOG000031444.
KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential."
    Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P., Baeumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G.
    J. Mol. Microbiol. Biotechnol. 7:204-211(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 13 / ATCC 14580 [Goettingen]Imported.

Entry informationi

Entry nameiQ65N57_BACLD
AccessioniPrimary (citable) accession number: Q65N57
Entry historyi
Integrated into UniProtKB/TrEMBL: October 25, 2004
Last sequence update: October 25, 2004
Last modified: October 29, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3