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Q65N57

- Q65N57_BACLD

UniProt

Q65N57 - Q65N57_BACLD

Protein

Alanine racemase

Gene

alr1

Organism
Bacillus licheniformis (strain DSM 13 / ATCC 14580)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (25 Oct 2004)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei42 – 421Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei140 – 1401SubstrateUniRule annotation
    Active sitei269 – 2691Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei316 – 3161Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:alr1Imported
    Ordered Locus Names:BLi00551Imported
    OrganismiBacillus licheniformis (strain DSM 13 / ATCC 14580)Imported
    Taxonomic identifieri279010 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
    ProteomesiUP000000608: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei42 – 421N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliQ65N57.
    SMRiQ65N57. Positions 6-385.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000031444.
    KOiK01775.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q65N57-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMSLKPFYRK TWAEIDLTAL KENVRNMKRH IGEHVRLMAV VKANAYGHGD    50
    AQVAKAALAE GASILAVALL DEALSLRAQG IEEPILVLGA VPTEYASIAA 100
    EKRIIVTGYS VGWLKDVLGF LNEAEAPLEY HLKIDTGMGR LGCKTEEEIK 150
    EMMEMTESND KLNCTGVFTH FATADEKDTD YFNMQLDRFK ELISPLPLDR 200
    LMVHSSNSAA GLRFREQLFN AVRFGIGMYG LAPSTEIKDE LPFRLREVFS 250
    LHTELTHVKK IKKGESVSYG ATYTAQRDEW IGTVPVGYAD GWLRRLAGTE 300
    VLIDGKRQKI AGRICMDQFM ISLAEEYPVG TKVTLIGKQK DEWISVDEIA 350
    QNLQTINYEI TCMISSRVPR MFLENGSIME IRNPILPDQS 390
    Length:390
    Mass (Da):43,743
    Last modified:October 25, 2004 - v1
    Checksum:i17678550ED2D3C02
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017333 Genomic DNA. Translation: AAU39507.1.
    RefSeqiWP_011201566.1. NC_006322.1.
    YP_006711978.1. NC_006322.1.

    Genome annotation databases

    EnsemblBacteriaiAAU39507; AAU39507; BLi00551.
    GeneIDi3097603.
    KEGGibld:BLi00551.
    PATRICi18946619. VBIBacLic203714_0548.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017333 Genomic DNA. Translation: AAU39507.1 .
    RefSeqi WP_011201566.1. NC_006322.1.
    YP_006711978.1. NC_006322.1.

    3D structure databases

    ProteinModelPortali Q65N57.
    SMRi Q65N57. Positions 6-385.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAU39507 ; AAU39507 ; BLi00551 .
    GeneIDi 3097603.
    KEGGi bld:BLi00551.
    PATRICi 18946619. VBIBacLic203714_0548.

    Phylogenomic databases

    HOGENOMi HOG000031444.
    KOi K01775.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential."
      Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P., Baeumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G.
      J. Mol. Microbiol. Biotechnol. 7:204-211(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 13 / ATCC 14580 [Goettingen]Imported.

    Entry informationi

    Entry nameiQ65N57_BACLD
    AccessioniPrimary (citable) accession number: Q65N57
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 25, 2004
    Last sequence update: October 25, 2004
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3