Q65N07 (GCP_BACLD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	BLi00615, BL00845

Organism

Bacillus licheniformis (strain DSM 13 / ATCC 14580) [Complete proteome] [HAMAP]

Taxonomic identifier

279010 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 341	341	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303268

Sequences

	Sequence		Length	Mass (Da)
	Q65N07 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: 6749839970941212	FASTA	341	36,165
	10 20 30 40 50 60 MNHKKDLYVL GIETSCDETA AAIVKNGTDI ISNVVASQIE SHKRFGGVVP EIASRHHVEQ 70 80 90 100 110 120 ITIVLEEAFA QADMTFDDID AIAVTEGPGL VGALLIGVNA AKALSFARGI PLVGVHHIAG 130 140 150 160 170 180 HIYANRLVQD IQFPAIALVV SGGHTELVYM KEHGSFEVIG ETLDDAAGEA YDKVARTMGL 190 200 210 220 230 240 PYPGGPHIDK LAQKGEANVP LPRAWLEEGS YHFSFSGLKS AVINTLHNAS QKGETIAPED 250 260 270 280 290 300 LSASFQESVI DVLVTKTERA AEAYGVKQVL LAGGVAANKG LRAALEKTFS SRPEIELLIP 310 320 330 340 PLSLCTDNAA MIAAAGTVAF EKGIRGKYDM NGQPGLDLTS Y

References

[1]

"The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential." Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P., Baeumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G. J. Mol. Microbiol. Biotechnol. 7:204-211(2004) [PubMed: 15383718] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 13 / ATCC 14580.

[2]

"Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species." Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J., Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B., Rasmussen M.D., Andersen J.T., Joergensen P.L., Larsen T.S., Sorokin A., Bolotin A., Lapidus A. , Galleron N., Ehrlich S.D., Berka R.M. Genome Biol. 5:R77.1-R77.12(2004) [PubMed: 15461803] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 13 / ATCC 14580.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000002 Genomic DNA. Translation: AAU22203.1. AE017333 Genomic DNA. Translation: AAU39557.1.
RefSeq	YP_077841.1. NC_006270.3. YP_090250.1. NC_006322.1.
3D structure databases
ProteinModelPortal	Q65N07.
ModBase	Search...
Protein-protein interaction databases
STRING	Q65N07.
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000054199; EBBACP00000052730; EBBACG00000054190. EBBACT00000061519; EBBACP00000059952; EBBACG00000061510.
GeneID	3030735. 3098308.
GenomeReviews	Gene locus BLi00615 in contig AE017333_GR. Gene locus BL00845 in contig CP000002_GR.
KEGG	bld:BLi00615. bli:BL00845.
NMPDR	fig|279010.5.peg.830.
PATRIC	18946749. VBIBacLic203714_0599.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0533.
GeneTree	EBGT00050000002496.
HOGENOM	HBG304663.
OMA	PAVGVHH.
PhylomeDB	Q65N07.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	BLIC279010-1:BLI00615-MONOMER. BLIC279010:BL00845-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_BACLD

Accession

Primary (citable) accession number: Q65N07
Secondary accession number(s): Q62YF5

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	October 25, 2004
Last modified:	January 25, 2012
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program