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Protein

Guanylate kinase

Gene

gmk

Organism
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi12 – 19ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBLIC279010:G1G12-1805-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:BLi01789, BL02293
OrganismiBacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Taxonomic identifieri279010 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000000606 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002662881 – 204Guanylate kinaseAdd BLAST204

Proteomic databases

PRIDEiQ65JT0

Interactioni

Protein-protein interaction databases

STRINGi279010.BLi01789

Structurei

3D structure databases

ProteinModelPortaliQ65JT0
SMRiQ65JT0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 184Guanylate kinase-likeUniRule annotationAdd BLAST180

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UHA Bacteria
COG0194 LUCA
HOGENOMiHOG000037639
KOiK00942
OMAiAGNYYGT

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q65JT0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKERGLLIVL SGPSGVGKGT VRQALFAQED TKFEYSISVT TRKPRQGERD
60 70 80 90 100
GVDYFFKTRE EFEEMIENNK LLEWAEYVGN YYGTPVDYVE QTLESGRDVF
110 120 130 140 150
LEIEVQGALQ VRKAFPEGLF IFLAPPSLAE LKNRIVTRGT ETEATIENRM
160 170 180 190 200
KAAKEEIELM DAYDYVVEND SIELACERIK AIVLAEHLRR DRVAPRYKKM

LEVE
Length:204
Mass (Da):23,469
Last modified:October 25, 2004 - v1
Checksum:iD39E17632B99BCBC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017333 Genomic DNA Translation: AAU40684.1
CP000002 Genomic DNA Translation: AAU23324.2
RefSeqiWP_011197968.1, NC_006322.1

Genome annotation databases

EnsemblBacteriaiAAU23324; AAU23324; BL02293
AAU40684; AAU40684; BLi01789
GeneIDi3030944
KEGGibld:BLi01789
bli:BL02293
PATRICifig|279010.13.peg.1789

Similar proteinsi

Entry informationi

Entry nameiKGUA_BACLD
AccessioniPrimary (citable) accession number: Q65JT0
Secondary accession number(s): Q62V85
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: October 25, 2004
Last modified: May 23, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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