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Q65IW0 (UXUA2_BACLD) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannonate dehydratase 2
EC=4.2.1.8
Alternative name(s):
D-mannonate hydrolase 2
Gene names
Name:uxuA2
Ordered Locus Names:BLi02116, BL00281
OrganismBacillus licheniformis (strain DSM 13 / ATCC 14580) [Complete proteome] [HAMAP]
Taxonomic identifier279010 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length356 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106

Pathway

Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106

Sequence similarities

Belongs to the mannonate dehydratase family.

Ontologies

Keywords
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglucuronate catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionmannonate dehydratase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 356356Mannonate dehydratase 2 HAMAP MF_00106
PRO_0000231048

Sequences

Sequence LengthMass (Da)Tools
Q65IW0 [UniParc].

Last modified October 25, 2004. Version 1.
Checksum: F3293B5FCD5F964D

FASTA35640,830
        10         20         30         40         50         60 
MQMTFRWYGD SDPVTLEYIR QIPGVTGIVS AIYDIPVGEA WPYEKIVELK EKIENHGLSL 

        70         80         90        100        110        120 
SVIESVPVHE DIKLGLPTRD QYIENYKTTI RNLAKAGVKI VCYNFMPVFD WTRSSLDYAL 

       130        140        150        160        170        180 
EDGSTALIYE EEKVRQMNPL HGELKLPGWD TSYEDGQLKN LFQQYQHMTE EDLWENLSYF 

       190        200        210        220        230        240 
IKAVIPAAEN EQVKMAIHPD DPPWPIFGLP RIITNKENLE RLIHLYDSSF NGLCLCSGSL 

       250        260        270        280        290        300 
GVKSTNDIPE LIRYFGKKGK VNFVHLRNIK IIGEKSFQES SHRSEDGSLD MYEIVRALRD 

       310        320        330        340        350 
IDFAGPARPD HGRMIWGETG KPGYGLYDRA LGAVYLNGMW ETLTKEKKRI ALECNK

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References

[1]"The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential."
Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P., Baeumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G.
J. Mol. Microbiol. Biotechnol. 7:204-211(2004) [PubMed: 15383718] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 13 / ATCC 14580.
[2]"Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species."
Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J., Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B., Rasmussen M.D., Andersen J.T., Joergensen P.L., Larsen T.S., Sorokin A., Bolotin A., Lapidus A. expand/collapse author list , Galleron N., Ehrlich S.D., Berka R.M.
Genome Biol. 5:R77.1-R77.12(2004) [PubMed: 15461803] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 13 / ATCC 14580.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017333 Genomic DNA. Translation: AAU41004.1.
CP000002 Genomic DNA. Translation: AAU23641.2.
RefSeqYP_079279.2. NC_006270.3.
YP_091697.1. NC_006322.1.

3D structure databases

ProteinModelPortalQ65IW0.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ65IW0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000054395; EBBACP00000052926; EBBACG00000054386.
EBBACT00000061779; EBBACP00000060212; EBBACG00000061770.
GeneID3031397.
3101007.
GenomeReviewsGene locus BLi02116 in contig AE017333_GR.
Gene locus BL00281 in contig CP000002_GR.
KEGGbld:BLi02116.
bli:BL00281.
NMPDRfig|279010.5.peg.2813.
PATRIC18949849. VBIBacLic203714_2128.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1312.
GeneTreeEBGT00050000001836.
HOGENOMHBG585927.
ProtClustDBPRK03906.

Enzyme and pathway databases

BioCycBLIC279010-1:BLI02116-MONOMER.
BLIC279010:BL00281-MONOMER.

Family and domain databases

HAMAPMF_00106. UxuA.
[Tree]
InterProIPR004628. Man_deHydtase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KOK01686.
PfamPF03786. UxuA. 1 hit.
[Graphical view]
PIRSFPIRSF016049. Man_dehyd. 1 hit.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR00695. UxuA. 2 hits.
ProtoNetSearch...

Entry information

Entry nameUXUA2_BACLD
AccessionPrimary (citable) accession number: Q65IW0
Secondary accession number(s): Q62UB8
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: October 25, 2004
Last modified: January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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