Reviewed, UniProtKB/Swiss-Prot Q65ID2 (MSRB_BACLD)

Names and origin

Protein names

Recommended name:
    Peptide methionine sulfoxide reductase msrB
    EC=1.8.4.12
Alternative name(s):
    Peptide-methionine (R)-S-oxide reductase

Gene names

Name:	msrB
Ordered Locus Names:	BLi02302, BL01422

Organism

Bacillus licheniformis (strain DSM 13 / ATCC 14580) [Complete proteome] [HAMAP]

Taxonomic identifier

279010 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	151 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Sequence similarities	Belongs to the msrB Met sulfoxide reductase family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 151	151	Peptide methionine sulfoxide reductase msrB HAMAP MF_01400		PRO_1000068264
Sites
	Active site	116	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q65ID2-1 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: 6B75B4643CF3569C	FASTA	151	17,215
	10 20 30 40 50 60 MTNNKEERLK QLTRMQYEVT QKNGTEPPFQ NEYWDLHEDG IYVDIVSGKP LFSSLDKFDA 70 80 90 100 110 120 HCGWPSFTKP VDAGEIEEKL DTSHGMIRTE VRSKSADSHL GHVFPDGPGP DGLRYCINSA 130 140 150 ALRFVPKDDL EKEGYGEYVK LFERKKSGEE S

References

[1]

"The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential." Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P., Baeumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G. J. Mol. Microbiol. Biotechnol. 7:204-211(2004) [PubMed: 15383718] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species." Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J., Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B., Rasmussen M.D., Andersen J.T., Joergensen P.L., Larsen T.S., Sorokin A., Bolotin A., Lapidus A. , Galleron N., Ehrlich S.D., Berka R.M. Genome Biol. 5:RESEARCH077.1-RESEARCH077.12(2004) [PubMed: 15461803] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000002 Genomic DNA. Translation: AAU23826.1. AE017333 Genomic DNA. Translation: AAU41182.1.
RefSeq	YP_079464.1. YP_091875.1.
3D structure databases
SMR	Q65ID2. Positions 1-144.
ModBase	Search...
Genome annotation databases
GeneID	3027519. 3101328.
GenomeReviews	Gene locus BLi02302 in contig AE017333_GR. Gene locus BL01422 in contig CP000002_GR.
KEGG	bld:BLi02302. bli:BL01422.
NMPDR	fig|279010.5.peg.68.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q65ID2.
OMA	Q65ID2. KYESGCG.
Enzyme and pathway databases
BioCyc	BLIC279010:BL01422-MON.
Family and domain databases
HAMAP	MF_01400. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
ProDom	PD004057. DUF25. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00357. MsrB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MSRB_BACLD

Accession

Primary (citable) accession number: Q65ID2
Secondary accession number(s): Q62TT3

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	October 25, 2004
Last modified:	June 16, 2009
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)