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Protein

Chorismate mutase AroH

Gene

aroH

Organism
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.UniRule annotation

Catalytic activityi

Chorismate = prephenate.UniRule annotation

Pathwayi: prephenate biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes prephenate from chorismate.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Chorismate mutase AroH (aroH)
This subpathway is part of the pathway prephenate biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes prephenate from chorismate, the pathway prephenate biosynthesis and in Metabolic intermediate biosynthesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei7 – 71SubstrateUniRule annotation
Binding sitei90 – 901SubstrateUniRule annotation
Binding sitei108 – 1081SubstrateUniRule annotation
Binding sitei116 – 1161SubstrateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesisUniRule annotation

Enzyme and pathway databases

BioCyciBLIC279010:GJ2P-2393-MONOMER.
UniPathwayiUPA00120; UER00203.

Names & Taxonomyi

Protein namesi
Recommended name:
Chorismate mutase AroHUniRule annotation (EC:5.4.99.5UniRule annotation)
Gene namesi
Name:aroHImported
Ordered Locus Names:BL02776Imported
OrganismiBacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)Imported
Taxonomic identifieri279010 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000000606 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi279010.BLi02404.

Structurei

3D structure databases

ProteinModelPortaliQ65I30.
SMRiQ65I30. Positions 1-127.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105KHN. Bacteria.
COG4401. LUCA.
HOGENOMiHOG000043606.
KOiK06208.
OMAiCIRVMMT.
OrthoDBiEOG6WT8J3.

Family and domain databases

Gene3Di3.30.1330.40. 1 hit.
InterProiIPR008243. Chorismate_mutase_AroH.
IPR013813. Endoribo_LPSP/chorism_mut-like.
[Graphical view]
PANTHERiPTHR21164. PTHR21164. 1 hit.
PfamiPF07736. CM_1. 1 hit.
[Graphical view]
PIRSFiPIRSF005965. Chor_mut_AroH. 1 hit.
ProDomiPD031888. Chorismate_mutase_AroH. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF55298. SSF55298. 1 hit.
TIGRFAMsiTIGR01796. CM_mono_aroH. 1 hit.
PROSITEiPS51167. CHORISMATE_MUT_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q65I30-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMMRGIRGAT TIDRDTEKDI TERTKQLIGK MIDENRLKPE QVVQILISAT
60 70 80 90 100
SDIHAAFPAK VVRTFDGWQH VPVMCMQEMD VEHGLKKCIR VMMTVQTDMR
110 120
QDEVRHVYLE NAVTLRPDLS LTKNTEL
Length:127
Mass (Da):14,669
Last modified:October 25, 2004 - v1
Checksum:iFBD101D8AAAD6F1A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000002 Genomic DNA. Translation: AAU23930.1.
RefSeqiWP_003182984.1. NC_006322.1.

Genome annotation databases

EnsemblBacteriaiAAU23930; AAU23930; BL02776.
GeneIDi3028676.
KEGGibli:BL02776.
PATRICi18950468. VBIBacLic203714_2436.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000002 Genomic DNA. Translation: AAU23930.1.
RefSeqiWP_003182984.1. NC_006322.1.

3D structure databases

ProteinModelPortaliQ65I30.
SMRiQ65I30. Positions 1-127.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi279010.BLi02404.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAU23930; AAU23930; BL02776.
GeneIDi3028676.
KEGGibli:BL02776.
PATRICi18950468. VBIBacLic203714_2436.

Phylogenomic databases

eggNOGiENOG4105KHN. Bacteria.
COG4401. LUCA.
HOGENOMiHOG000043606.
KOiK06208.
OMAiCIRVMMT.
OrthoDBiEOG6WT8J3.

Enzyme and pathway databases

UniPathwayiUPA00120; UER00203.
BioCyciBLIC279010:GJ2P-2393-MONOMER.

Family and domain databases

Gene3Di3.30.1330.40. 1 hit.
InterProiIPR008243. Chorismate_mutase_AroH.
IPR013813. Endoribo_LPSP/chorism_mut-like.
[Graphical view]
PANTHERiPTHR21164. PTHR21164. 1 hit.
PfamiPF07736. CM_1. 1 hit.
[Graphical view]
PIRSFiPIRSF005965. Chor_mut_AroH. 1 hit.
ProDomiPD031888. Chorismate_mutase_AroH. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF55298. SSF55298. 1 hit.
TIGRFAMsiTIGR01796. CM_mono_aroH. 1 hit.
PROSITEiPS51167. CHORISMATE_MUT_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46Imported.

Entry informationi

Entry nameiQ65I30_BACLD
AccessioniPrimary (citable) accession number: Q65I30
Secondary accession number(s): Q62TH9
Entry historyi
Integrated into UniProtKB/TrEMBL: October 25, 2004
Last sequence update: October 25, 2004
Last modified: July 6, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.