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Q65I21 (Q65I21_BACLD) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
GTP cyclohydrolase 1 HAMAP MF_00223
EC=3.5.4.16 HAMAP MF_00223
Alternative name(s):
GTP cyclohydrolase I HAMAP MF_00223
Gene names
Name:mtrA EMBL AAU41293.1
Synonyms:folE HAMAP MF_00223
Ordered Locus Names:BL02786, BLi02413
OrganismBacillus licheniformis (strain DSM 13 / ATCC 14580) [Complete proteome] [HAMAP]
Taxonomic identifier279010 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length189 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate. SAAS SAAS001474 HAMAP MF_00223

Pathway

Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1. SAAS SAAS001474 HAMAP MF_00223

Subunit structure

Homopolymer By similarity. HAMAP MF_00223

Sequence similarities

Belongs to the GTP cyclohydrolase I family. HAMAP MF_00223

Sequences

Sequence LengthMass (Da)Tools
Q65I21 [UniParc].

Last modified October 25, 2004. Version 1.
Checksum: F1938E3DCD5BE3DB

FASTA18921,068
        10         20         30         40         50         60 
MREINKDQIE QAVRQILEAI GEDPNREGLL DTPKRVAKMY AEVFAGLNED PKEHFKTIFG 

        70         80         90        100        110        120 
EDHEELVLVK DIPFYSMCEH HLVPFYGKAH VAYIPKGGKV TGLSKLARAV EAVAKRPQLQ 

       130        140        150        160        170        180 
ERITSTIADS IVETLTPHGV MVVVEAEHMC MTMRGVKKPG SKTVTSAVRG TFRQDVAARS 


EVLELIKTS

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References

[1]"The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential."
Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P., Baeumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G.
J. Mol. Microbiol. Biotechnol. 7:204-211(2004) [PubMed: 15383718] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 13 / ATCC 14580 [Goettingen].
[2]"Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species."
Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J., Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B., Rasmussen M.D., Andersen J.T., Joergensen P.L., Larsen T.S., Sorokin A., Bolotin A., Lapidus A. expand/collapse author list , Galleron N., Ehrlich S.D., Berka R.M.
Genome Biol. 5:R77.1-R77.12(2004) [PubMed: 15461803] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 13 / ATCC 14580 [Novozymes].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000002 Genomic DNA. Translation: AAU23940.1.
AE017333 Genomic DNA. Translation: AAU41293.1.
RefSeqYP_079578.1. NC_006270.3.
YP_091986.1. NC_006322.1.

3D structure databases

ProteinModelPortalQ65I21.
SMRQ65I21. Positions 3-188.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ65I21.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000057519; EBBACP00000056050; EBBACG00000057510.
EBBACT00000061417; EBBACP00000059850; EBBACG00000061408.
GeneID3029322.
3098779.
GenomeReviewsGene locus BLi02413 in contig AE017333_GR.
Gene locus BL02786 in contig CP000002_GR.
KEGGbld:BLi02413.
bli:BL02786.
NMPDRfig|279010.5.peg.264.
PATRIC18950486. VBIBacLic203714_2445.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0302.
GeneTreeEBGT00050000002882.
HOGENOMHBG370191.
OMALPFMGRA.
PhylomeDBQ65I21.
ProtClustDBPRK09347.

Family and domain databases

HAMAPMF_00223. FolE.
[Tree]
InterProIPR001474. GTP_CycHdrlase_I.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
IPR018234. GTP_CycHdrlase_I_CS.
[Graphical view]
KOK01495.
PANTHERPTHR11109. GTP_cyclohydro_I. 1 hit.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
TIGRFAMsTIGR00063. FolE. 1 hit.
PROSITEPS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
PS00860. GTP_CYCLOHYDROL_1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ65I21_BACLD
AccessionPrimary (citable) accession number: Q65I21
Secondary accession number(s): Q62TG9
Entry history
Integrated into UniProtKB/TrEMBL: October 25, 2004
Last sequence update: October 25, 2004
Last modified: January 25, 2012
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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