Reviewed, UniProtKB/Swiss-Prot Q65H75 (SYGA_BACLD)

Names and origin

Protein names

Recommended name:
    Glycyl-tRNA synthetase alpha subunit
    EC=6.1.1.14
Alternative name(s):
    Glycine--tRNA ligase alpha subunit
      Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	BLi02718, BL03676

Organism

Bacillus licheniformis (strain DSM 13 / ATCC 14580) [Complete proteome] [HAMAP]

Taxonomic identifier

279010 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	295 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00254
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glycine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 295	295	Glycyl-tRNA synthetase alpha subunit HAMAP MF_00254		PRO_1000047398

Sequences

	Sequence		Length	Mass (Da)
	Q65H75-1 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: E2AA4F4ECC1B2566	FASTA	295	34,174
	10 20 30 40 50 60 MNIQEMILTL QKHWSNEGCV LLQSYDVEKG AGTMSPYTFL RSLGPEPWKV AYVEPSRRPA 70 80 90 100 110 120 DGRYGDNPNR LYQHHQFQVI IKPSPDNIQE LYLDSLKALG IDPLEHDIRF VEDNWENPSL 130 140 150 160 170 180 GCAGLGWEVW LDGMEITQFT YFQQVGGLEC KPVSVEITYG IERLASYIQD KENVFDLEWT 190 200 210 220 230 240 NGYTIKDLFK MAEYEHSVYT FETSDVDMLF ELFATYEKEA NRQMDQGLVH PAYDYVLKCS 250 260 270 280 290 HTFNLLDAKG AISVTERTGY IARVRNLARK VAKTYYDERE KLGFPMLKEE EASHE

References

[1]

"The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential." Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P., Baeumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G. J. Mol. Microbiol. Biotechnol. 7:204-211(2004) [PubMed: 15383718] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species." Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J., Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B., Rasmussen M.D., Andersen J.T., Joergensen P.L., Larsen T.S., Sorokin A., Bolotin A., Lapidus A. , Galleron N., Ehrlich S.D., Berka R.M. Genome Biol. 5:RESEARCH077.1-RESEARCH077.12(2004) [PubMed: 15461803] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000002 Genomic DNA. Translation: AAU24226.1. AE017333 Genomic DNA. Translation: AAU41589.1.
RefSeq	YP_079864.1. YP_092282.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q65H75.
Genome annotation databases
GeneID	3027751. 3097714.
GenomeReviews	Gene locus BLi02718 in contig AE017333_GR. Gene locus BL03676 in contig CP000002_GR.
KEGG	bld:BLi02718. bli:BL03676.
NMPDR	fig|279010.5.peg.561.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q65H75.
OMA	CRRPTDG.
Enzyme and pathway databases
BioCyc	BLIC279010:BL03676-MON.
Family and domain databases
HAMAP	MF_00254. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
ProDom	PD006985. tRNA_synt_2e. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00388. glyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_BACLD

Accession

Primary (citable) accession number: Q65H75
Secondary accession number(s): Q62SN3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 25, 2004
Last modified:	November 3, 2009
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)